Peptide Vaccine Formulation Controls the Duration of Antigen Presentation and Magnitude of Tumor-Specific CD8+T Cell Response

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

(2017) Ugur Sahin et al.   NATURE

An immunogenic personal neoantigen vaccine for patients with melanoma

(2017) Patrick A. Ott et al.   NATURE

Adjuvants for peptide-based cancer vaccines

(2016) Hiep Khong et al.   Journal for ImmunoTherapy of Cancer

Nanoparticulate STING agonists are potent lymph node–targeted vaccine adjuvants

(2015) Melissa C. Hanson et al.   JOURNAL OF CLINICAL INVESTIGATION

Neoantigens in cancer immunotherapy

(2015) T. N. Schumacher et al.   SCIENCE

Engineering New Approaches to Cancer Vaccines

(2015) N. K. Mehta et al.   Cancer Immunology Research

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

The Adjuvants Aluminum Hydroxide and MF59 Induce Monocyte and Granulocyte Chemoattractants and Enhance Monocyte Differentiation toward Dendritic Cells

(2014) A. Seubert et al.   JOURNAL OF IMMUNOLOGY

Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

(2014) Matthew M. Gubin et al.   NATURE

Structure-based programming of lymph-node targeting in molecular vaccines

(2014) Haipeng Liu et al.   NATURE

Therapeutic vaccines for cancer: an overview of clinical trials

(2014) Ignacio Melero et al.   Nature Reviews Clinical Oncology

A sharp T-cell antigen receptor signaling threshold for T-cell proliferation

(2014) B. B. Au-Yeung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-1 enhances expansion, effector function, tissue localization, and memory response of antigen-specific CD8 T cells

(2013) Shlomo Z. Ben-Sasson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Persistent antigen at vaccination sites induces tumor-specific CD8+ T cell sequestration, dysfunction and deletion

(2013) Yared Hailemichael et al.   NATURE MEDICINE

Nanoparticle vaccines

(2013) Liang Zhao et al.   VACCINE

Antigen Incorporated In Virus-like Particles Is Delivered to Specific Dendritic Cell Subsets That Induce An Effective Antitumor Immune Response In Vivo

(2012) Kunyu Li et al.   JOURNAL OF IMMUNOTHERAPY

Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival

(2012) Steffen Walter et al.   NATURE MEDICINE

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

Virus-like particles as a highly efficient vaccine platform: Diversity of targets and production systems and advances in clinical development

(2012) Natasha Kushnir et al.   VACCINE

Nanoparticle Delivery of Cancer Drugs

(2011) Andrew Z. Wang et al.   Annual Review of Medicine

Tyrosine Isomers Mediate the Classical Phenomenon of Concomitant Tumor Resistance

(2011) R. A. Ruggiero et al.   CANCER RESEARCH

PEGylation of Proteins and Liposomes: a Powerful and Flexible Strategy to Improve the Drug Delivery

(2011) Paola Milla et al.   CURRENT DRUG METABOLISM

Antigen depot is not required for alum adjuvanticity

(2011) Sharon Hutchison et al.   FASEB JOURNAL

Cross-presentation of epitopes on virus-like particles via the MHC I receptor recycling pathway

(2011) Stephanie J Win et al.   IMMUNOLOGY AND CELL BIOLOGY

Duration of Antigen Availability Influences the Expansion and Memory Differentiation of T Cells

(2011) D. A. Blair et al.   JOURNAL OF IMMUNOLOGY

Therapeutic cancer vaccines: are we there yet?

(2010) Christopher A. Klebanoff et al.   IMMUNOLOGICAL REVIEWS

Self-antigen–specific CD8+T cell precursor frequency determines the quality of the antitumor immune response

(2009) Gabrielle A. Rizzuto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Complete but curtailed T-cell response to very low-affinity antigen

(2009) Dietmar Zehn et al.   NATURE

Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome

(2009) Fiona A. Sharp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recruitment of Antigen-Specific CD8+ T Cells in Response to Infection Is Markedly Efficient

(2009) J. W. J. van Heijst et al.   SCIENCE

Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation

(2008) Martijn S. Bijker et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

(2008) Stephanie C. Eisenbarth et al.   NATURE

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY