Multiple Levels of Control Determine How E4bp4/Nfil3 Regulates NK Cell Development

PDK1 orchestrates early NK cell development through induction of E4BP4 expression and maintenance of IL-15 responsiveness

(2015) Meixiang Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NFIL3 Orchestrates the Emergence of Common Helper Innate Lymphoid Cell Precursors

(2015) Wei Xu et al.   Cell Reports

Transcriptional Control of Early T and B Cell Developmental Choices

(2014) Ellen V. Rothenberg   Annual Review of Immunology

Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer

(2014) Yang Sui Brooks et al.   JOURNAL OF CLINICAL INVESTIGATION

Nfil3 is required for the development of all innate lymphoid cell subsets

(2014) Cyril Seillet et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The transcription factor E4bp4/Nfil3 controls commitment to the NK lineage and directly regulates Eomes and Id2 expression

(2014) Victoria Male et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Nfil3 is crucial for development of innate lymphoid cells and host protection against intestinal pathogens

(2014) Theresa L. Geiger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Transcription Factor E4BP4 Is Not Required for Extramedullary Pathways of NK Cell Development

(2014) S. Crotta et al.   JOURNAL OF IMMUNOLOGY

An in vitro model of innate lymphoid cell function and differentiation

(2014) D SJ Allan et al.   Mucosal Immunology

The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells

(2014) Antoine Marçais et al.   NATURE IMMUNOLOGY

Uncovering global SUMOylation signaling networks in a site-specific manner

(2014) Ivo A Hendriks et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Conversion of Adipose-Derived Stem Cells into Natural Killer-Like Cells with Anti-Tumor Activities in Nude Mice

(2014) Hongxiu Ning et al.   PLoS One

Ebola virus VP35 induces high-level production of recombinant TPL-2–ABIN-2–NF-κB1 p105 complex in co-transfected HEK-293 cells

(2013) Thorsten Gantke et al.   BIOCHEMICAL JOURNAL

Intraepithelial Type 1 Innate Lymphoid Cells Are a Unique Subset of IL-12- and IL-15-Responsive IFN-γ-Producing Cells

(2013) Anja Fuchs et al.   IMMUNITY

Intrinsic Selectivity of Notch 1 for Delta-like 4 Over Delta-like 1

(2013) Marie Blanke Andrawes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nfil3-independent lineage maintenance and antiviral response of natural killer cells

(2013) Matthew A. Firth et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway

(2013) Lucille C Rankin et al.   NATURE IMMUNOLOGY

TH17 Cell Differentiation Is Regulated by the Circadian Clock

(2013) X. Yu et al.   SCIENCE

Notch, Id2, and RORγt sequentially orchestrate the fetal development of lymphoid tissue inducer cells

(2012) Marie Cherrier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Novel Phosphorylation Sites in the S. cerevisiae Cdc13 Protein Reveal New Targets for Telomere Length Regulation

(2012) Yun Wu et al.   JOURNAL OF PROTEOME RESEARCH

Transcription factor RORα is critical for nuocyte development

(2012) See Heng Wong et al.   NATURE IMMUNOLOGY

NFIL3/E4BP4 controls type 2 T helper cell cytokine expression

(2011) Masaki Kashiwada et al.   EMBO JOURNAL

The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells

(2011) Yasutaka Motomura et al.   NATURE IMMUNOLOGY

Notch signaling is necessary for adult, but not fetal, development of RORγt+ innate lymphoid cells

(2011) Cécilie Possot et al.   NATURE IMMUNOLOGY

AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch

(2011) Jacob S Lee et al.   NATURE IMMUNOLOGY

Innate or Adaptive Immunity? The Example of Natural Killer Cells

(2011) E. Vivier et al.   SCIENCE

The phosphoproteome of toll-like receptor-activated macrophages

(2010) Gabriele Weintz et al.   Molecular Systems Biology

Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis

(2010) J. V. Olsen et al.   Science Signaling

Activated Notch Supports Development of Cytokine Producing NK Cells Which Are Hyporesponsive and Fail to Acquire NK Cell Effector Functions

(2009) Veronika Bachanova et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Notch signaling and the bone marrow hematopoietic stem cell niche

(2009) Jonathan M. Weber et al.   BONE

Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

(2009) Shintaro Kamizono et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Notch Activation Induces the Generation of Functional NK Cells from Human Cord Blood CD34-Positive Cells Devoid of IL-15

(2009) Kyoko Haraguchi et al.   JOURNAL OF IMMUNOLOGY

Notch Regulates Cytolytic Effector Function in CD8+ T Cells

(2009) O. H. Cho et al.   JOURNAL OF IMMUNOLOGY

Effect of Peptide-to-TiO2Beads Ratio on Phosphopeptide Enrichment Selectivity

(2009) Qing-run Li et al.   JOURNAL OF PROTEOME RESEARCH

The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development

(2009) Duncan M Gascoyne et al.   NATURE IMMUNOLOGY

Detection of protein SUMOylation in vivo

(2009) Michael H Tatham et al.   Nature Protocols

A quantitative atlas of mitotic phosphorylation

(2008) N. Dephoure et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA