Bruton’s Tyrosine Kinase Is Not Essential for B Cell Survival beyond Early Developmental Stages

Blimp-1–dependent and –independent natural antibody production by B-1 and B-1–derived plasma cells

(2017) Hannah P. Savage et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NF-κB signaling in B-1 cell development

(2015) Gabriel K. Pedersen et al.   Annals of the New York Academy of Sciences

The human counterpart of mouse B-1 cells

(2015) Thomas L. Rothstein et al.   Annals of the New York Academy of Sciences

B-1b Cells Secrete Atheroprotective IgM and Attenuate AtherosclerosisNovelty and Significance

(2015) Sam M. Rosenfeld et al.   CIRCULATION RESEARCH

Complement Factor H-Binding Protein, a Putative Virulence Determinant of Borrelia hermsii, Is an Antigenic Target for Protective B1b Lymphocytes

(2014) M. J. Colombo et al.   JOURNAL OF IMMUNOLOGY

Bruton's Tyrosine Kinase Promotes Persistence of Mature Anti-Insulin B Cells

(2014) R. H. Bonami et al.   JOURNAL OF IMMUNOLOGY

Modeling the Clinical Phenotype of BTK Inhibition in the Mature Murine Immune System

(2014) M. J. Benson et al.   JOURNAL OF IMMUNOLOGY

Natural IgM Is Produced by CD5−Plasma Cells That Occupy a Distinct Survival Niche in Bone Marrow

(2014) Alexander E. Reynolds et al.   JOURNAL OF IMMUNOLOGY

Splenic B-1a Cells Expressing CD138 Spontaneously Secrete Large Amounts of Immunoglobulin in Naïve Mice

(2014) Nichol E. Holodick et al.   Frontiers in Immunology

The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway

(2013) Edina Schweighoffer et al.   IMMUNITY

Human B1 Cell Frequency: Isolation and Analysis of Human B1 Cells

(2012) Daniel O. Griffin et al.   Frontiers in Immunology

B-1 cells in the bone marrow are a significant source of natural IgM

(2011) Youn Soo Choi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+CD27+CD43+CD70−

(2011) Daniel O. Griffin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Anergic Responses Characterize a Large Fraction of Human Autoreactive Naive B Cells Expressing Low Levels of Surface IgM

(2011) T. D. Quach et al.   JOURNAL OF IMMUNOLOGY

Programmed Cell Death 1 Suppresses B-1b Cell Expansion and Long-Lived IgG Production in Response to T Cell-Independent Type 2 Antigens

(2011) Karen M. Haas   JOURNAL OF IMMUNOLOGY

The Role of Bruton's Tyrosine Kinase in B-Cell Development and Function in Mice and Mana

(2010) WASIF N. KHAN et al.   Annals of the New York Academy of Sciences

Generation of B Cell Memory to the Bacterial Polysaccharide  -1,3 Dextran

(2009) J. B. Foote et al.   JOURNAL OF IMMUNOLOGY

Reduced Diabetes in btk-Deficient Nonobese Diabetic Mice and Restoration of Diabetes with Provision of an Anti-Insulin IgH Chain Transgene

(2009) P. L. Kendall et al.   JOURNAL OF IMMUNOLOGY

Continual signaling is responsible for constitutive ERK phosphorylation in B-1a cells

(2009) Nichol E. Holodick et al.   MOLECULAR IMMUNOLOGY

Antigen-specific B-1a antibodies induced by Francisella tularensis LPS provide long-term protection against F. tularensis LVS challenge

(2009) L. E. Cole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors

(2008) J. Andrew Duty et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Btk regulates localization, in vivo activation, and class switching of anti-DNA B cells

(2008) Kristina E. Halcomb et al.   MOLECULAR IMMUNOLOGY