Article
Public, Environmental & Occupational Health
Cheng Li, Ziqi Liu, Min Zhao, Cheng Zhang, Pascal Bovet, Bo Xi
Summary: This study examined the association between changes in weight status from birth to childhood and high blood pressure (BP) in children. The findings suggest that childhood weight has a greater impact on BP than birth weight, and children who had incident or persistently high weight from birth to childhood had increased odds of high BP. However, children who had high birth weight but changed to normal weight in childhood did not have significantly increased odds of high BP. These findings highlight the importance of maintaining appropriate weight in early life for the prevention of high BP and related diseases, especially for those with high birth weight.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Endocrinology & Metabolism
Yiyuan Zhang, Peihao Liu, Wei Zhou, Jingmei Hu, Linlin Cui, Zi-Jiang Chen
Summary: The aim of this study was to clarify the relationships between large for gestational age (LGA) and cardiometabolic risk factors. A meta-analysis of 42 studies involving 841,325 individuals showed that individuals born LGA had higher odds of overweight and obesity, type 1 diabetes, hypertension, and metabolic syndrome compared to those born appropriate for gestational age. No significant difference was found in hypertriglyceridemia and hypercholesterolemia.
Article
Cardiac & Cardiovascular Systems
Merida Rodriguez-Lopez, Alvaro Sepulveda-Martinez, Gabriel Bernardino, Francesca Crovetto, Carolina Pajuelo, Marta Sitges, Bart Bijnens, Eduard Gratacos, Fatima Crispi
Summary: This study assessed the differences in cardiometabolic health between adults born small for gestational age. The results showed that females born small for gestational age are more prone to cardiac dysfunction, while males are more likely to experience changes in electrocardiography, vascular health, and metabolism.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Medicine, General & Internal
Yulika Yoshida-Montezuma, Branavan Sivapathasundaram, Hilary K. Brown, Charles Keown-Stoneman, Russell J. de Souza, Teresa To, Cornelia M. Borkhoff, Catherine S. Birken, Jonathon L. Maguire, Laura N. Anderson
Summary: Children born late preterm and moderately preterm have higher cardiometabolic risk, suggesting that screening and early-life interventions for these children may prevent cardiometabolic outcomes.
Article
Pediatrics
Theodora Stathopoulou, Eleni Agakidou, Christos Paschaloudis, Angeliki Kontou, Ilias Chatzioannidis, Kosmas Sarafidis
Summary: This single-center retrospective cohort study aimed to evaluate the association between administering inotropes to hypotensive very low gestational age infants (VLGAI) and prenatal and neonatal risk factors. The study found that fentanyl, severe intraventricular hemorrhage (IVH), and gestational age (GA) were the risk factors most strongly associated with the need for inotrope treatment in VLGAI.
Article
Pediatrics
Christopher W. Course, Sarah J. Kotecha, Michael Cousins, Kylie Hart, John Lowe, W. John Watkins, Sailesh Kotecha
Summary: This study aimed to evaluate the associations of early and current life factors on cardiovascular health and to explore the cardiovascular changes in preterm-born and term-born children. The results showed that preterm-born children had higher central systolic blood pressure and augmentation index, indicating an increased risk of cardiovascular disease. However, the cardiovascular exercise responses were similar among all three groups.
JOURNAL OF PEDIATRICS
(2023)
Article
Pediatrics
Tomoyuki Shimokaze, Katsuaki Toyoshima, Tomoko Saito, Kaoru Katsumata, Takahiro Kemmotsu, Hiroshi Ishikawa, Kenji Kurosawa
Summary: This study examined the survival and developmental prognosis of preterm infants with Down syndrome in a neonatal intensive care unit. The results showed a high mortality rate for these infants, with bronchopulmonary dysplasia and pulmonary hypertension being significant contributors to death. A significant proportion of survivors also developed moderate to severe cerebral palsy.
PEDIATRIC RESEARCH
(2023)
Article
Pediatrics
Fen Yang, Imre Janszky, Mika Gissler, Sven Cnattingius, Nathalie Roos, Maohua Miao, Wei Yuan, Jiong Li, Krisztina D. Laszlo
Summary: Adverse birth outcomes such as preterm birth and large for gestational age (LGA) are associated with increased risks of atrial fibrillation (AF), while small for gestational age (SGA) births only have an increased risk of AF in childhood.
Article
Public, Environmental & Occupational Health
Camila Honorato A. Torres, Lidiane F. Schultz, Paul J. Veugelers, Silmara S. B. S. Mastroeni, Marco F. Mastroeni
Summary: The study found that maternal pre-pregnancy overweight and simultaneous excessive GWG were positively associated with elevated BP in 6-year-old children. Mothers with pre-pregnancy BMI ≥ 25 kg/m(2) and excessive GWG were more likely to have children with elevated diastolic blood pressure.
JOURNAL OF PUBLIC HEALTH
(2021)
Article
Endocrinology & Metabolism
Arash Derakhshan, Tuija Mannisto, Liangmiao Chen, Joris A. J. Osinga, Ghalia Ashoor, Xuemian Lu, Sofie Bliddal, Fang-Biao Tao, Suzanne J. Brown, Bijay Vaidya, Andrew T. Hattersley, Sachiko Itoh, Polina Popova, Ashraf Aminorroaya, Reiko Kishi, Maryam Kianpour, Elena A. Vasukova, Abel Lopez-Bermejo, Emily Oken, Leda Chatzi, Marina Vafeiadi, Wichor M. Bramer, Judit Bassols, Aitana Lertxundi, Ana Fernandez-Somoano, Paula Carrasco, Juha Auvinen, Kun Huang, Ulla Feldt-Rasmussen, Elena N. Grineva, Erik K. Alexander, Elizabeth N. Pearce, Layal Chaker, John P. Walsh, Robin P. Peeters, Monica Guxens, Eila Suvanto, Kypros H. Nicolaides, Tim I. M. Korevaar
Summary: This study explores the association between gestational FT3 and TT3 levels and adverse obstetric outcomes. The findings suggest that FT3 and TT3 levels have different associations with various adverse obstetric outcomes, with high TT3 associated with an increased risk of gestational hypertension and low TT3 associated with a higher risk of very preterm birth.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Public, Environmental & Occupational Health
Sanna Mustaniemi, Hilkka Nikkinen, Aini Bloigu, Anneli Pouta, Risto Kaaja, Johan G. Eriksson, Hannele Laivuori, Mika Gissler, Eero Kajantie, Marja Vaarasmaki
Summary: The study showed that normal gestational weight gain is associated with a lower risk of large-for-gestational-age infants and lower birth weight standard deviation scores in the presence of gestational diabetes and maternal obesity.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Pediatrics
Shi Chen, Shirui Wang, Tiantian Li, Huijuan Zhu, Yuelun Zhang, Siyu Liang, Yingying Yang, Hui Pan, Xiaoming Shi
Summary: This study reveals the association between PM2.5 exposure and large for gestational age (LGA) in China and establishes a trimester-specific relationship. Pregnant women in highly polluted areas are at a higher risk of giving birth to LGA infants.
PEDIATRIC RESEARCH
(2022)
Article
Multidisciplinary Sciences
Lan-Wan Wang, Hung-Chih Lin, Ming-Luen Tsai, Yu-Tzu Chang, Yu-Chia Chang
Summary: This study investigated the relationship between hypertensive disorders of pregnancy (HDP) and the risk of autism spectrum disorder (ASD) in children. It found that children born to mothers with HDP had higher rates of preterm-birth and small-for-gestational-age, both of which are risk factors for ASD. The study also suggested that HDP may not be a major contributor to ASD, but rather preterm-birth and SGA play a moderating role in increasing ASD risks.
SCIENTIFIC REPORTS
(2023)
Article
Cardiac & Cardiovascular Systems
Fatima Crispi, Merida Rodriguez-Lopez, Gabriel Bernardino, Alvaro Sepulveda-Martinez, Susanna Prat-Gonzalez, Carolina Pajuelo, Rosario J. Perea, Maria T. Caralt, Giulia Casu, Kilian Vellve, Francesca Crovetto, Felip Burgos, Mathieu De Craene, Constantine Butakoff, Miguel A. Gonzalez Ballester, Isabel Blanco, Marta Sitges, Bart Bijnens, Eduard Gratacos
Summary: This study evaluated the baseline cardiac function and structure as well as exercise capacity in young adults born small for gestational age (SGA). The results showed that these young adults had markedly reduced exercise capacity, indicating potential association with increased cardiovascular mortality.
Article
Nutrition & Dietetics
Jing Ouyang, Yuwei Lai, Linjing Wu, Yi Wang, Ping Wu, Yi-Xiang Ye, Xue Yang, Yanyu Gao, Jiaying Yuan, Xingyue Song, Shijiao Yan, Chuanzhu Lv, Yi-Xin Wang, Gang Liu, Yayi Hu, An Pan, Xiong-Fei Pan
Summary: This study investigated the association between weight change from age 18 to pregnancy and gestational diabetes mellitus (GDM) among Chinese pregnant women. The results showed that weight change was linearly associated with a higher risk of GDM, and excessive weight gain increased the risk even more. Maintaining weight stability, especially preventing excessive weight gain from early adulthood to pregnancy, could be a potential strategy to reduce GDM risk.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Pediatrics
Xia Zeng, Li Cai, Stephen Heung-sang Wong, Lijuan Lai, Yajie Lv, Weiqing Tan, Jin Jing, Yajun Chen
Summary: This study found that low sedentary time and high physical activity were positively associated with executive function development in children. Particularly, children with high sedentary time and high physical activity showed more significant deficits in executive function, suggesting intervention efforts should focus on reducing sedentary time in addition to promoting physical activity.
ACADEMIC PEDIATRICS
(2021)
Article
Clinical Neurology
Yajie Lv, Li Cai, Xia Zeng, Zhaohuan Gui, Lijuan Lai, Weiqing Tan, Yajun Chen
JOURNAL OF CLINICAL SLEEP MEDICINE
(2020)
Review
Pediatrics
Xiaomin Sun, Yixuan Li, Li Cai, Youfa Wang
Summary: Physical activity interventions can improve core executive functions and non-executive functions among overweight and obese youth, with interventions focusing on adiposity measures showing greater improvement in core executive functions. However, they do not positively influence metacognition and academic performance. The effect of physical activity characteristics on cognitive performance should be considered, with short-term programs possibly benefiting core executive functions.
PEDIATRIC RESEARCH
(2021)
Article
Endocrinology & Metabolism
Li Cai, Weijia Wu, Lizi Lin, Yajun Chen, Rui Gao, Bijun Shi, Bingjie Ma, Yuming Chen, Jin Jing
JOURNAL OF DIABETES INVESTIGATION
(2020)
Article
Public, Environmental & Occupational Health
Zhaohuan Gui, Li Cai, Jingshu Zhang, Xia Zeng, Lijuan Lai, Yajie Lv, Cunrui Huang, Yajun Chen
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2020)
Article
Nutrition & Dietetics
Qian Chen, Yajun Chen, Weijia Wu, Nu Tang, Dongyu Wang, Yuming Chen, Jin Jing, Li Cai
Summary: The study found that a low-carbohydrate dietary pattern with high animal protein and fat is positively associated with higher postprandial 1-hour glucose levels in Chinese pregnant women. However, this association became non-significant after adjusting for covariates.
BRITISH JOURNAL OF NUTRITION
(2021)
Article
Endocrinology & Metabolism
Nu Tang, Yajun Chen, Weijia Wu, Wenting Pan, Dongyu Wang, Jingshu Zhang, Kaiyun Tan, Jin Jing, Li Cai
Summary: Plasma irisin levels in mid-pregnancy were negatively associated with fasting blood glucose levels and impaired fasting glucose at 6-8 weeks postpartum among Chinese women, with stronger associations observed in women with higher blood glucose values. Additionally, breastfeeding may modify this relationship.
JOURNAL OF DIABETES INVESTIGATION
(2021)
Article
Public, Environmental & Occupational Health
Lizi Lin, Guanghui Dong, Nu Tang, Yajun Chen, Li Cai
Summary: The study in Guangzhou found a negative association between residential greenness and HbA1c levels in pregnant women, but no significant association with plasma glucose levels or the risk of GDM. The results suggest that incorporating green infrastructure in urban design and planning could contribute to promoting maternal health.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2021)
Article
Nutrition & Dietetics
Nu Tang, Yang Wu, Yajun Chen, Qian Chen, Weijia Wu, Jin Jing, Li Cai
Summary: The study examined the association between postpartum low-carbohydrate diet scores and glucose levels, finding a positive correlation between animal low-carbohydrate diet scores and fasting plasma glucose levels, primarily in women with lower fasting plasma glucose levels.
Article
Nutrition & Dietetics
Jingjing Zeng, Weijia Wu, Yajun Chen, Jin Jing, Li Cai
Summary: Maternal dietary protein patterns during pregnancy were found to be associated with infant eczema risk, with plant and dairy and eggs patterns linked to a reduced risk of eczema in infants.
FRONTIERS IN NUTRITION
(2021)
Article
Nutrition & Dietetics
Saijun Huang, Xin Wang, Tao Sun, Hong Yu, Yanwei Liao, Muqing Cao, Li Cai, Xiuhong Li, Lizi Lin, Xi Su, Jin Jing
Summary: Previous studies have shown that exclusive breastfeeding is associated with lower odds of having ASD in children. This cross-sectional study conducted in seven cities in China found that toddlers with partial breastfeeding or without breastfeeding had higher odds of having ASD compared to those with exclusive breastfeeding.
Article
Pediatrics
Yujing Chen, Lizi Lin, Bin Hong, Shamshad Karatela, Wenting Pan, Shengchi Wu, Nu Tang, Yuxuan Wang, Jin Jing, Li Cai
Summary: The study found that allergic nasal and ocular symptoms in 2-year-old children were associated with frequent nighttime awakenings and irregular sleep, while allergic gastrointestinal symptoms were associated with shortened nighttime sleep duration and increased irregular sleep. Multiple allergic symptoms were significantly associated with shortened nighttime sleep duration and increased irregular sleep.
FRONTIERS IN PEDIATRICS
(2022)
Article
Public, Environmental & Occupational Health
Zhaohuan Gui, Li Cai, Yajie Lv, Lijuan Lai, Xia Zeng, Yajun Chen
Summary: This study found a positive association between the number of ideal cardiovascular health metrics and executive function in children in China, particularly with metacognition indexes. Ideal diet and physical activity were independently associated with behavioral regulation and metacognition.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Nutrition & Dietetics
Weijia Wu, Nu Tang, Jingjing Zeng, Jin Jing, Li Cai
Summary: This study investigated the association between dietary protein patterns and the risk of gestational diabetes mellitus (GDM) in pregnant women. The results showed that higher intakes of total protein and animal protein during pregnancy increased the risk of GDM. Furthermore, compared to women with a plant-dairy-eggs protein pattern, women with a red meat or white meat protein pattern had a higher risk of GDM.
Article
Nutrition & Dietetics
Shanshan Peng, Zhicheng Du, Yannan He, Feng Zhao, Yujing Chen, Shengchi Wu, Yuantao Hao, Li Cai
Summary: This study investigated the association between maternal erythrocyte PUFA levels and offspring allergies in the Chinese population. The findings revealed that higher levels of total PUFA, particularly arachidonic acid and n-3 PUFA, were associated with a reduced risk of offspring allergies. The associations were stronger in children with a maternal allergy history.
