Hepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients

Role of insulin receptor substrates in the progression of hepatocellular carcinoma

(2017) Yoshitaka Sakurai et al.   Scientific Reports

Metabolic Impact of Nonalcoholic Steatohepatitis in Obese Patients With Type 2 Diabetes

(2016) Romina Lomonaco et al.   DIABETES CARE

2. Classification and Diagnosis of Diabetes

(2016)   DIABETES CARE

Prevalence of Prediabetes and Type 2 Diabetes in Children With Nonalcoholic Fatty Liver Disease

(2016) Kimberly P. Newton et al.   JAMA Pediatrics

Chronic Ethanol-Induced Impairment of Wnt/β-Catenin Signaling is Attenuated by PPAR-δAgonist

(2015) Chelsea Q. Xu et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

β-Catenin Signaling and Roles in Liver Homeostasis, Injury, and Tumorigenesis

(2015) Satdarshan Pal Monga   GASTROENTEROLOGY

The SRE Motif in the Human PNPLA3 Promoter (−97 to −88 bp) Mediates Transactivational Effects of SREBP-1c

(2015) Hua Liang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The intrahepatic expression levels of bile acid transporters are inversely correlated with the histological progression of nonalcoholic fatty liver disease

(2015) Kazuya Okushin et al.   JOURNAL OF GASTROENTEROLOGY

Restoration of Wnt/β-catenin signaling attenuates alcoholic liver disease progression in a rat model

(2015) Chiung-Kuei Huang et al.   JOURNAL OF HEPATOLOGY

BMI-related progression of atypical PKC-dependent aberrations in insulin signaling through IRS-1, Akt, FoxO1 and PGC-1α in livers of obese and type 2 diabetic humans

(2015) Mini P. Sajan et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

β-Catenin Links Hepatic Metabolic Zonation with Lipid Metabolism and Diet-Induced Obesity in Mice

(2014) Jaideep Behari et al.   AMERICAN JOURNAL OF PATHOLOGY

Deciphering liver zonation: New insights into the β-catenin, Tcf4, and HNF4α triad

(2014) Carmen Berasain et al.   HEPATOLOGY

The β-catenin pathway contributes to the effects of leptin on SREBP-1c expression in rat hepatic stellate cells and liver fibrosis

(2013) Xuguang Zhai et al.   BRITISH JOURNAL OF PHARMACOLOGY

Prevalence of Prediabetes and Diabetes and Metabolic Profile of Patients With Nonalcoholic Fatty Liver Disease (NAFLD)

(2012) C. Ortiz-Lopez et al.   DIABETES CARE

Excessive Hepatic Mitochondrial TCA Cycle and Gluconeogenesis in Humans with Nonalcoholic Fatty Liver Disease

(2011) Nishanth E. Sunny et al.   Cell Metabolism

Why Does NAFLD Predict Type 2 Diabetes?

(2011) Guido Lattuada et al.   Current Diabetes Reports

Liver Enzymes Are Associated With Hepatic Insulin Resistance, Insulin Secretion, and Glucagon Concentration in Healthy Men and Women

(2011) F. Bonnet et al.   DIABETES

Elevated Liver Function Enzymes Are Related to the Development of Prediabetes and Type 2 Diabetes in Younger Adults: The Bogalusa Heart Study

(2011) Q. M. Nguyen et al.   DIABETES CARE

Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease

(2011) Silvia Sookoian et al.   HEPATOLOGY

Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease

(2011) Romina Lomonaco et al.   HEPATOLOGY

Nine-year incident diabetes is predicted by fatty liver indices: the French D.E.S.I.R. study

(2010) Beverley Balkau et al.   BMC GASTROENTEROLOGY

Tumor formation in liver of conditional  -catenin-deficient mice exposed to a diethylnitrosamine/phenobarbital tumor promotion regimen

(2010) B. Rignall et al.   CARCINOGENESIS

Insulin Resistance in Nonalcoholic Fatty Liver Disease

(2010) E. Bugianesi et al.   CURRENT PHARMACEUTICAL DESIGN

Wnt signaling regulates mitochondrial physiology and insulin sensitivity

(2010) J. C. Yoon et al.   GENES & DEVELOPMENT

Conditional β-catenin loss in mice promotes chemical hepatocarcinogenesis: Role of oxidative stress and platelet-derived growth factor receptor α/phosphoinositide 3-kinase signaling

(2010) Xu-Feng Zhang et al.   HEPATOLOGY

Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes

(2010) Céline Dubuquoy et al.   JOURNAL OF HEPATOLOGY

Lessons learned from studying families genetically predisposed to type 2 diabetes mellitus

(2009) Kenneth Cusi   Current Diabetes Reports

Alanine Aminotransferase,  -Glutamyltransferase, and Incident Diabetes: The British Women's Heart and Health Study and meta-analysis

(2009) A. Fraser et al.   DIABETES CARE

IRS1Regulation by Wnt/β-Catenin Signaling and Varied Contribution ofIRS1to the Neoplastic Phenotype

(2009) Guido T. Bommer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nonalcoholic fatty liver is a risk factor for postprandial hyperglycemia, but not for impaired fasting glucose

(2009) Tomoko Shiga et al.   JOURNAL OF GASTROENTEROLOGY

Activation of Wnt/β-Catenin Signaling Increases Insulin Sensitivity through a Reciprocal Regulation of Wnt10b and SREBP-1c in Skeletal Muscle Cells

(2009) Mounira Abiola et al.   PLoS One

Dynamic Functional Relay between Insulin Receptor Substrate 1 and 2 in Hepatic Insulin Signaling during Fasting and Feeding

(2008) Naoto Kubota et al.   Cell Metabolism

Increased Liver Fat, Impaired Insulin Clearance, and Hepatic and Adipose Tissue Insulin Resistance in Type 2 Diabetes

(2008) Anna Kotronen et al.   GASTROENTEROLOGY

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS