Thrombopoietin protects hematopoietic stem cells from retrotransposon-mediated damage by promoting an antiviral response
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Title
Thrombopoietin protects hematopoietic stem cells from retrotransposon-mediated damage by promoting an antiviral response
Authors
Keywords
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Journal
JOURNAL OF EXPERIMENTAL MEDICINE
Volume 215, Issue 5, Pages 1463-1480
Publisher
Rockefeller University Press
Online
2018-04-04
DOI
10.1084/jem.20170997
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Note: Only part of the references are listed.- Enhanced thrombopoietin but not G-CSF receptor stimulation induces self-renewing hematopoietic stem cell divisions in vivo
- (2016) L. V. Kovtonyuk et al. BLOOD
- How retrotransposons shape genome regulation
- (2016) Paolo Mita et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Engineered LINE-1 retrotransposition in nondividing human neurons
- (2016) Angela Macia et al. GENOME RESEARCH
- L1-associated genomic regions are deleted in somatic cells of the healthy human brain
- (2016) Jennifer A Erwin et al. NATURE NEUROSCIENCE
- Retrotransposons as regulators of gene expression
- (2016) R. A. Elbarbary et al. SCIENCE
- Age-Associated Decrease of the Histone Methyltransferase SUV39H1 in HSC Perturbs Heterochromatin and B Lymphoid Differentiation
- (2016) Dounia Djeghloul et al. Stem Cell Reports
- Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
- (2015) Katherine B. Chiappinelli et al. CELL
- Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors
- (2015) Simon Haas et al. Cell Stem Cell
- Type I Interferon Controls Propagation of Long Interspersed Element-1
- (2015) Qiujing Yu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Post-transcriptional gene silencing triggered by sense transgenes involves uncapped antisense RNA and differs from silencing intentionally triggered by antisense transgenes
- (2015) Jean-Sébastien Parent et al. NUCLEIC ACIDS RESEARCH
- Contrasting Roles for C/EBPα and Notch in Irradiation-Induced Multipotent Hematopoietic Progenitor Cell Defects
- (2015) Courtney Jo Fleenor et al. STEM CELLS
- Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome
- (2015) Luke Isbel et al. PLoS Genetics
- SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation
- (2015) Siqi Hu et al. PLoS Genetics
- The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition
- (2015) John L. Goodier et al. PLoS Genetics
- Progressive Chromatin Condensation and H3K9 Methylation Regulate the Differentiation of Embryonic and Hematopoietic Stem Cells
- (2015) Fernando Ugarte et al. Stem Cell Reports
- Interferon-Stimulated Genes: A Complex Web of Host Defenses
- (2014) William M. Schneider et al. Annual Review of Immunology
- Total body irradiation causes long-term mouse BM injury via induction of HSC premature senescence in an Ink4a- and Arf-independent manner
- (2014) L. Shao et al. BLOOD
- Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal
- (2014) Deqiang Sun et al. Cell Stem Cell
- A Role for Retrotransposon LINE-1 in Fetal Oocyte Attrition in Mice
- (2014) Safia Malki et al. DEVELOPMENTAL CELL
- Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons
- (2014) Eric M. Pietras et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells
- (2014) Johanna Flach et al. NATURE
- Repair of DNA double-strand breaks by templated nucleotide sequence insertions derived from distant regions of the genome
- (2014) M. Onozawa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age
- (2014) Michael Van Meter et al. Nature Communications
- Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon- in a murine model of polycythemia vera
- (2013) A. Mullally et al. BLOOD
- JAK2V617F expression in mice amplifies early hematopoietic cells and gives them a competitive advantage that is hampered by IFN
- (2013) S. Hasan et al. BLOOD
- SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage
- (2013) R. Clifford et al. BLOOD
- IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage
- (2013) HyeonJoo Cheon et al. EMBO JOURNAL
- Resilient and resourceful: Genome maintenance strategies in hematopoietic stem cells
- (2013) Sietske T. Bakker et al. EXPERIMENTAL HEMATOLOGY
- DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape
- (2013) Mingchao Xie et al. NATURE GENETICS
- Trim24-repressed VL30 retrotransposons regulate gene expression by producing noncoding RNA
- (2013) Benjamin Herquel et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- RNase L restricts the mobility of engineered retrotransposons in cultured human cells
- (2013) Ao Zhang et al. NUCLEIC ACIDS RESEARCH
- Viral protein R of human immunodeficiency virus type-1 induces retrotransposition of long interspersed element-1
- (2013) Kenta Iijima et al. Retrovirology
- Modulation of LINE-1 and Alu/SVA Retrotransposition by Aicardi-Goutières Syndrome-Related SAMHD1
- (2013) Ke Zhao et al. Cell Reports
- Retroviruses, retroelements and their restrictions
- (2013) Atsushi Koito et al. Frontiers in Microbiology
- Single-Neuron Sequencing Analysis of L1 Retrotransposition and Somatic Mutation in the Human Brain
- (2012) Gilad D. Evrony et al. CELL
- Thrombopoietin-Increased DNA-PK-Dependent DNA Repair Limits Hematopoietic Stem and Progenitor Cell Mutagenesis in Response to DNA Damage
- (2012) Bérengère de Laval et al. Cell Stem Cell
- Extensive somatic L1 retrotransposition in colorectal tumors
- (2012) S. Solyom et al. GENOME RESEARCH
- IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome
- (2012) Laura Belloni et al. JOURNAL OF CLINICAL INVESTIGATION
- INTERFEROME v2.0: an updated database of annotated interferon-regulated genes
- (2012) Irina Rusinova et al. NUCLEIC ACIDS RESEARCH
- Landscape of Somatic Retrotransposition in Human Cancers
- (2012) E. Lee et al. SCIENCE
- MOV10 RNA Helicase Is a Potent Inhibitor of Retrotransposition in Cells
- (2012) John L. Goodier et al. PLoS Genetics
- Integrin- v 3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells
- (2011) T. Umemoto et al. BLOOD
- Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition
- (2011) Lixin Dai et al. BMC BIOCHEMISTRY
- Involvement of retrotransposition of long interspersed nucleotide element-1 in skin tumorigenesis induced by 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol-13-acetate
- (2011) Noriyuki Okudaira et al. CANCER SCIENCE
- Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility
- (2011) Silke Wissing et al. HUMAN MOLECULAR GENETICS
- Somatic retrotransposition alters the genetic landscape of the human brain
- (2011) J. Kenneth Baillie et al. NATURE
- Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells
- (2011) N. G. Coufal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Natural Mutagenesis of Human Genomes by Endogenous Retrotransposons
- (2010) Rebecca C. Iskow et al. CELL
- L1 retrotransposition in neurons is modulated by MeCP2
- (2010) Alysson R. Muotri et al. NATURE
- Somatic expression of LINE-1 elements in human tissues
- (2010) Victoria P. Belancio et al. NUCLEIC ACIDS RESEARCH
- L1 retrotransposition occurs mainly in embryogenesis and creates somatic mosaicism
- (2009) H. Kano et al. GENES & DEVELOPMENT
- L1 retrotransposition in human neural progenitor cells
- (2009) Nicole G. Coufal et al. NATURE
- IFNα activates dormant haematopoietic stem cells in vivo
- (2009) Marieke A. G. Essers et al. NATURE
- The regulated retrotransposon transcriptome of mammalian cells
- (2009) Geoffrey J Faulkner et al. NATURE GENETICS
- DNA Damage, Aging, and Cancer
- (2009) Jan H.J. Hoeijmakers NEW ENGLAND JOURNAL OF MEDICINE
- Phenotypic and Functional Changes Induced in Hematopoietic Stem/Progenitor Cells After Gamma-Ray Radiation Exposure
- (2009) Arthur J. Simonnet et al. STEM CELLS
- Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity
- (2008) Daniel B. Stetson et al. CELL
- Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells
- (2008) Ricardo Rajsbaum et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Clonal chromosome anomalies and propensity to myeloid malignancies in congenital amegakaryocytic thrombocytopenia (OMIM 604498)
- (2008) E. Maserati et al. HAEMATOLOGICA
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