miR-221 stimulates breast cancer cells and cancer-associated fibroblasts (CAFs) through selective interference with the A20/c-Rel/CTGF signaling

Development and validation of a bioanalytical method for quantification of LNA-i-miR-221, a 13-mer oligonucleotide, in rat plasma using LC–MS/MS

(2018) S. Franzoni et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

MiR-222 promotes drug-resistance of breast cancer cells to adriamycin via modulation of PTEN/Akt/FOXO1 pathway

(2017) Hongyu Shen et al.   GENE

MicroRNA-222 Expression as a Predictive Marker for Tumor Progression in Hormone Receptor-Positive Breast Cancer

(2017) Song-Hee Han et al.   Journal of Breast Cancer

Maintenance of stemness is associated with the interation of LRP6 and heparin-binding protein CCN2 autocrined by hepatocellular carcinoma

(2017) Qingan Jia et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

A20, an essential component of the ubiquitin-editing protein complex, is a negative regulator of inflammation in human myometrium and foetal membranes

(2017) Martha Lappas   MOLECULAR HUMAN REPRODUCTION

miR-221 activates the NF-κB pathway by targeting A20

(2016) Dongjiu Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNAs in colorectal carcinoma - from pathogenesis to therapy

(2016) Yudan Chi et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Targeting microRNAs as key modulators of tumor immune response

(2016) Laura Paladini et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Pharmacokinetics and Pharmacodynamics of a 13-mer LNA-inhibitor-miR-221 in Mice and Non-human Primates

(2016) Maria Eugenia Gallo Cantafio et al.   Molecular Therapy-Nucleic Acids

A potential role for CCN2/CTGF in aggressive colorectal cancer

(2016) Inge Ubink et al.   Journal of Cell Communication and Signaling

The Overexpression of TGF-β and CCN2 in Intrauterine Adhesions Involves the NF-κB Signaling Pathway

(2016) Xiang Xue et al.   PLoS One

Ultrasonographic Features of Triple-Negative Breast Cancer: a Comparison with Other Breast Cancer Subtypes

(2015) Qi Yang et al.   Asian Pacific Journal of Cancer Prevention

MicroRNA let-7 Modulates the Immune Response to Mycobacterium tuberculosis Infection via Control of A20, an Inhibitor of the NF-κB Pathway

(2015) Manish Kumar et al.   Cell Host & Microbe

A 13 mer LNA-i-miR-221 Inhibitor Restores Drug Sensitivity in Melphalan-Refractory Multiple Myeloma Cells

(2015) A. Gulla et al.   CLINICAL CANCER RESEARCH

Prognostic and biological significance of microRNA-221 in breast cancer

(2015) Sanaa Eissa et al.   GENE

CCN2 Expression by Tumor Stroma Is Required for Melanoma Metastasis

(2015) James Hutchenreuther et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells

(2015) Walid T. Khaled et al.   Nature Communications

Estrogenic gper signaling regulates mir144 expression in cancer cells and cancer-associated fibroblasts (cafs)

(2015) Adele Vivacqua et al.   Oncotarget

MicroRNA regulation of molecular pathways as a generic mechanism and as a core disease phenotype

(2015) Rotem Ben-Hamo et al.   Oncotarget

In Vitro and in Vivo Anti-tumor Activity of miR-221/222 Inhibitors in Multiple Myeloma

(2015) Maria Teresa Di Martino et al.   Oncotarget

Estrogen receptor, Progesterone receptor, HER2 status and Ki67 index and responsiveness to adjuvant tamoxifen in postmenopausal high-risk breast cancer patients enrolled in the DBCG 77C trial

(2014) Ann S. Knoop et al.   EUROPEAN JOURNAL OF CANCER

Interleukin-17 (IL-17)-induced MicroRNA 873 (miR-873) Contributes to the Pathogenesis of Experimental Autoimmune Encephalomyelitis by Targeting A20 Ubiquitin-editing Enzyme

(2014) Xiaomei Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In Vitro and In Vivo Activity of a Novel Locked Nucleic Acid (LNA)-Inhibitor-miR-221 against Multiple Myeloma Cells

(2014) Maria Teresa Di Martino et al.   PLoS One

The tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20) imposes a brake on antitumor activity of CD8 T cells

(2014) M. Giordano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone Methyltransferase Ash1l Suppresses Interleukin-6 Production and Inflammatory Autoimmune Diseases by Inducing the Ubiquitin-Editing Enzyme A20

(2013) Meng Xia et al.   IMMUNITY

The inhibitory role of Mir-29 in growth of breast cancer cells

(2013) Zhenglong Wu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Invasive lobular breast cancer: subtypes and outcome

(2012) Monica Iorfida et al.   BREAST CANCER RESEARCH AND TREATMENT

MicroRNA-203 suppresses cell proliferation and migration by targeting BIRC5 and LASP1 in human triple-negative breast cancer cells

(2012) Chen Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

MicroRNAs miR-125a and miR-125b constitutively activate the NF- B pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20)

(2012) S.-W. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GPER mediates the Egr-1 expression induced by 17β-estradiol and 4-hydroxitamoxifen in breast and endometrial cancer cells

(2011) Adele Vivacqua et al.   BREAST CANCER RESEARCH AND TREATMENT

Aldosterone stimulates nuclear factor-kappa B activity and transcription of intercellular adhesion molecule-1 and connective tissue growth factor in rat mesangial cells via serum- and glucocorticoid-inducible protein kinase-1

(2011) Yoshio Terada et al.   Clinical and Experimental Nephrology

A20-binding Inhibitor of Nuclear Factor-κB (NF-κB)-2 (ABIN-2) Is an Activator of Inhibitor of NF-κB (IκB) Kinase α (IKKα)-mediated NF-κB Transcriptional Activity

(2011) Laurent Leotoing et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

Cancer-associated fibroblasts are positively correlated with metastatic potential of human gastric cancers

(2010) Kangkang Zhi et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

MicroRNA-21 regulates breast cancer invasion partly by targeting tissue inhibitor of metalloproteinase 3 expression

(2010) Bao Song et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Subtyping of Breast Cancer by Immunohistochemistry to Investigate a Relationship between Subtype and Short and Long Term Survival: A Collaborative Analysis of Data for 10,159 Cases from 12 Studies

(2010) Fiona M. Blows et al.   PLOS MEDICINE

Connective tissue growth factor: Context-dependent functions and mechanisms of regulation

(2009) Iwona Cicha et al.   BIOFACTORS

The Role of Tumor Cell-Derived Connective Tissue Growth Factor (CTGF/CCN2) in Pancreatic Tumor Growth

(2009) K. L. Bennewith et al.   CANCER RESEARCH

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

A20 Negatively Regulates T Cell Receptor Signaling to NF- B by Cleaving Malt1 Ubiquitin Chains

(2009) M. Duwel et al.   JOURNAL OF IMMUNOLOGY

The role of the NFκB signalling pathway in cancer

(2008) María Cortés Sempere et al.   Clinical & Translational Oncology

NF-KappaB expression correlates with apoptosis and angiogenesis in clear cell renal cell carcinoma tissues

(2008) Ibrahim Meteoglu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma

(2008) F Fornari et al.   ONCOGENE

Expression of connective tissue growth factor in tumor tissues is an independent predictor of poor prognosis in patients with gastric cancer

(2008) Lu-Ying Liu et al.   WORLD JOURNAL OF GASTROENTEROLOGY