Article
Cardiac & Cardiovascular Systems
Takashi Nakashima, Masaru Nagase, Taro Shibahara, Daiju Ono, Takehiro Yamada, Gen Tanabe, Keita Suzuki, Makoto Yamaura, Takahisa Ido, Shigekiyo Takahashi, Takuma Aoyama
Summary: This article described a type 1 Brugada electrocardiogram and discussed the potential diagnostic electrocardiographic indicators to differentiate true Brugada syndrome and Brugada phenocopy.
JOURNAL OF ELECTROCARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Elia De Maria, Ambra Borghi, Laura Tonelli, Rita Selvatici, Stefano Cappelli, Francesca Gualandi
Summary: Phenocopy refers to a condition that imitates one produced by a gene, and is also used for acquired Brugada-like ECG manifestations. Two patients with Hypertrophic Cardiomyopathy (HCM) and Brugada ECG pattern were described, both carrying the same pathogenic splicing mutation in MYBPC3 gene responsible for HCM, with no genetic mutation associated with Brugada Syndrome identified. Brugada ECG pattern is rarely reported in patients with HCM.
JOURNAL OF ELECTROCARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Janaki Rami Reddy Manne, Jalaj Garg
Summary: The passage illustrates the reversible nature of Brugada Type 1 pattern on electrocardiogram in hyperkalemia, emphasizing the importance of timely identification and management of reversible pathology to avoid unnecessary cardiac interventions.
JOURNAL OF ARRHYTHMIA
(2021)
Editorial Material
Cardiac & Cardiovascular Systems
Alice Bernardelli, Filippo Dossi, Mario Raccis, Roberto Maggi, Michele Brignole, Guido Parodi
Summary: An asymptomatic 56-year-old man with type 2 Brugada pattern, inducible ventricular fibrillation, and family history of sudden cardiac death, who had an Implantable Cardioverter-Defibrillator implanted, was admitted to the hospital 17 years later due to palpitations related to atrial flutter. Unexpectedly, a transthoracic echocardiogram revealed clinically manifest hypertrophic cardiomyopathy.
JOURNAL OF ELECTROCARDIOLOGY
(2023)
Article
Medicine, General & Internal
Ermias S. Greffie, Saleh Alhalaseh, Lynn Zaremski
Summary: Brugada syndrome is a hereditary channelopathy causing malignant ventricular arrhythmia and sudden death in individuals with a structurally normal heart, characterized by ST-segment elevation. Brugada phenocopy refers to conditions that result in identical ST morphologies without the actual underlying channelopathy. It is a rare manifestation of hyperkalemia, commonly associated with malignant arrhythmia.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Cardiac & Cardiovascular Systems
Satyajit Singh, Chandra Thakur, Surendra Naik, Muneshwar Kumar
Summary: Hyperkalemia-induced Brugada ECG pattern is a rare condition. It is important to be aware of this presentation because the treatment of this Brugada Phenocopy is different from Brugada syndrome. In this case, the patient presented with a Brugada-like ECG but had hyperkalemia. The ECG returned to normal after correcting the hyperkalemia.
JOURNAL OF THE PRACTICE OF CARDIOVASCULAR SCIENCES
(2022)
Article
Emergency Medicine
Olga Amusina, Sandeep Mehta, Michael E. Nelson
Summary: This case report highlights a 26-year-old male patient who presented with syncope and showed a Brugada-like pattern on ECG. Further examination revealed severe hyponatremia and moderate hyperkalemia, along with other metabolic disturbances. The patient was diagnosed with primary adrenal insufficiency, and the Brugada phenocopy resolved after electrolyte correction.
JOURNAL OF THE AMERICAN COLLEGE OF EMERGENCY PHYSICIANS OPEN
(2022)
Review
Cardiac & Cardiovascular Systems
Laszlo Littmann
Summary: Mistakes in ECG interpretation software can result in incorrect diagnoses and treatments, but sometimes these errors can also hide important clues that may have been missed. This article presents common and clinically significant peculiarities related to computer errors in ECG interpretation, along with tools to prove or disprove suspected diagnoses.
JOURNAL OF ELECTROCARDIOLOGY
(2023)