g-C3N4 nanofibers doped poly(3,4-ethylenedioxythiophene) modified electrode for simultaneous determination of ascorbic acid and acetaminophen

A fast and sensitive electrochemical sensor for simultaneous determination of ascorbic acid (AA) and acetaminophen (AP) was proposed based on g-C3N4 nanofibers (h-CN) doped poly(3,4-ethylenedioxy-thiophene) (PEDOT) composite. PEDOT/h-CN hybrid film was directly deposited on glass carbon electrode (GCE) by in-situ electropolymerization. The incorporation of h-CN and PEDOT brought out enhanced electro-catalytic activity and additional binding sites for AA and AP, which could be ascribed to the synergetic effect between h-CN and PEDOT. Under the optimal experimental condition, the oxidation peak currents of AA and AP give linear response over the range of 4-20 mu M, 20-1800 mu M and 1-10 mu M, 10-50 mu M, respectively. The detection limit of the modified electrode was calculated to be 1.51 mu M for AA and 0.49 mu M for AP (S/N = 3). The electrochemical experiments also suggested that PEDOT/h-CN modified electrode was feasible practice for quantitative detection of AA and AP.