Sclerostin and DKK1 Inhibition Preserves and Augments Alveolar Bone Volume and Architecture in Rats with Alveolar Bone Loss

Tumor necrosis factor-α antagonist diminishes osteocytic RANKL and sclerostin expression in diabetes rats with periodontitis

(2017) Ji-Hye Kim et al.   PLoS One

Time-dependent cellular and transcriptional changes in the osteoblast lineage associated with sclerostin antibody treatment in ovariectomized rats

(2016) Scott Taylor et al.   BONE

Romosozumab Improves Bone Mass and Strength While Maintaining Bone Quality in Ovariectomized Cynomolgus Monkeys

(2016) Michael S Ominsky et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Romosozumab Treatment in Postmenopausal Women with Osteoporosis

(2016) Felicia Cosman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sclerostin is essential for alveolar bone loss in occlusal hypofunction

(2016) YANG XU et al.   Experimental and Therapeutic Medicine

A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair

(2016) Monica Florio et al.   Nature Communications

Changes in the spatial distribution of sclerostin in the osteocytic lacuno-canalicular system in alveolar bone due to orthodontic forces, as detected on multimodal confocal fluorescence imaging analyses

(2015) Yuriko Nishiyama et al.   ARCHIVES OF ORAL BIOLOGY

Sclerostin antibody treatment causes greater alveolar crest height and bone mass in an ovariectomized rat model of localized periodontitis

(2015) Hui Chen et al.   BONE

Differential temporal effects of sclerostin antibody and parathyroid hormone on cancellous and cortical bone and quantitative differences in effects on the osteoblast lineage in young intact rats

(2015) Michael S. Ominsky et al.   BONE

Removal of SOST or blocking its product sclerostin rescues defects in the periodontitis mouse model

(2015) Yinshi Ren et al.   FASEB JOURNAL

Sclerostin Antibody Treatment Improves Implant Fixation in a Model of Severe Osteoporosis

(2015) Amarjit S. Virdi et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Involvement of the Wnt-β-catenin signalling antagonists, sclerostin and dickkopf-related protein 1, in chronic periodontitis

(2014) Marcelo Henrique Napimoga et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Bone Morphogenetic Proteins

(2014) A.C. Carreira et al.   JOURNAL OF DENTAL RESEARCH

Histochemical Localization of Dickkopf-1 in Induced Rat Periapical Lesions

(2014) Rui Zhang et al.   JOURNAL OF ENDODONTICS

Receptor Activator of Nuclear Factor-κB Ligand and Sclerostin Expression in Osteocytes of Alveolar Bone in Rats With Ligature-Induced Periodontitis

(2014) Ji-Hye Kim et al.   JOURNAL OF PERIODONTOLOGY

Romosozumab in Postmenopausal Women with Low Bone Mineral Density

(2014) Michael R. McClung et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sclerostin antibody stimulates bone regeneration after experimental periodontitis

(2013) Andrei D Taut et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Low BMD affects initial stability and delays stem osseointegration in cementless total hip arthroplasty in women

(2012) Hannu T Aro et al.   Acta Orthopaedica

Sclerostin and Dickkopf-1 as Therapeutic Targets in Bone Diseases

(2012) Hua Zhu Ke et al.   ENDOCRINE REVIEWS

The effects of Dickkopf-1 antibody on metaphyseal bone and implant fixation under different loading conditions

(2011) Fredrik Agholme et al.   BONE

A systematic review of post-extractional alveolar hard and soft tissue dimensional changes in humans

(2011) Wah Lay Tan et al.   CLINICAL ORAL IMPLANTS RESEARCH

Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury

(2011) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Post-natal Effect of Overexpressed DKK1 on Mandibular Molar Formation

(2011) X.L. Han et al.   JOURNAL OF DENTAL RESEARCH

A Rate-Limiting Role for Dickkopf-1 in Bone Formation and the Remediation of Bone Loss in Mouse and Primate Models of Postmenopausal Osteoporosis by an Experimental Therapeutic Antibody

(2011) H. Glantschnig et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Mechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engendered

(2011) A. Moustafa et al.   OSTEOPOROSIS INTERNATIONAL

Complications in Bone Grafting

(2011) Alan S. Herford et al.   Oral and Maxillofacial Surgery Clinics of North America

Bone loss in the oral cavity

(2010) Marjorie K. Jeffcoat   JOURNAL OF BONE AND MINERAL RESEARCH

Sclerostin antibody treatment enhances metaphyseal bone healing in rats

(2010) Fredrik Agholme et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Teriparatide and Osseous Regeneration in the Oral Cavity

(2010) Jill D. Bashutski et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sclerostin Mediates Bone Response to Mechanical Unloading Through Antagonizing Wnt/β-Catenin Signaling

(2009) Chuwen Lin et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Localization ofSOST/sclerostin in cementocytesin vivoand in mineralizing periodontal ligament cellsin vitro

(2009) A. Jäger et al.   JOURNAL OF PERIODONTAL RESEARCH

Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis*

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH