Article
Dentistry, Oral Surgery & Medicine
Rafael Siqueira, Khaled Sinjab, Ying-Chun Pan, Fabiana Soki, Hsun-Liang Chan, Oliver Kripfgans
Summary: The study aimed to explore the feasibility of ultrasonography (US) for imaging peri-implant tissues, showing high correlations between US measurements and CBCT as well as direct readings for crestal bone thickness and facial bone level. US was found to be a useful method for evaluating peri-implant facial crestal bone dimensions, and blood flow imaging could provide valuable information on inflammation severity.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Deng-Hui Duan, Hom-Lay Wang, Wu-Cai Xiao, Zheng Liu, En-Bo Wang
Summary: In the short-term, titanium plate-enhanced GBR maintained ridge dimensions better than conventional GBR did.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Mustafa Tattan, Omar Tattan, Jad Majzoub, Ali Salami, Hsun-Liang Chan, Oliver D. Kripfgans
Summary: This study demonstrates the feasibility of using 3D ultrasound to measure ridge width of the jawbone. 3D ultrasound can provide a larger field of view and more accurate positioning, making it a promising tool to supplement CBCT.
JOURNAL OF DENTISTRY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Ali Bushahri, Oliver D. Kripfgans, Furat George, I-Ching Wang, Hom-Lay Wang, Hsun-Liang Chan
Summary: In the intermediate term, peri-implant tissues, including mucosal level change of immediately placed implants with immediate provisionalization or delayed restoration, remained stable and did not differ between the groups. The final crown angle, influenced by implant position and abutment angle, might be associated with mucosal margin level change.
JOURNAL OF PERIODONTOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Danijel Domic, Kristina Bertl, Salman Ahmad, Lars Schropp, Kristina Hellen-Halme, Andreas Stavropoulos
Summary: In this study, it was found that buccal bone thickness significantly affects the accuracy of cone-beam computed tomography scans in determining the buccal bone level at dental titanium implants. Specifically, when buccal bone thickness is <= 1 mm, the detection accuracy of the buccal bone level is low.
JOURNAL OF PERIODONTOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Maria Vera Rodriguez, Andrea Ravida, Muhammad H. A. Saleh, Hussein S. Basma, Himabindu Dukka, Hadiya Khurshid, Hom-Lay Wang, Pablo Galindo Moreno
Summary: This retrospective study investigated the association between the amount of initial physiological bone remodeling (IPBR) during the first year of implant placement and the incidence of peri-implantitis as well as the pattern of progressive bone loss. The results showed no significant association between IPBR and peri-implantitis, but splinted implants had a higher marginal bone loss rate compared to non-splinted implants from T1 to T2.
JOURNAL OF PERIODONTOLOGY
(2022)
Review
Infectious Diseases
Asma Gasmi Benahmed, Amin Gasmi, Torsak Tippairote, Pavan Kumar Mujawdiya, Oleksandr Avdeev, Yurii Shanaida, Geir Bjorklund
Summary: Dental implants are commonly used to replace lost teeth, and titanium implants have a high success rate. However, there is an increasing risk of peri-implantitis, an inflammatory disease that affects the tissues around the implant. This review highlights the impact of different metabolic conditions on peri-implantitis and emphasizes the importance of considering both local and systemic factors in dental implant procedures and treatment.
Article
Dentistry, Oral Surgery & Medicine
Ramon Pons, Miguel Carreno, Ettore Amerio, Jordi Gargallo-Albiol, Jose Nart, Alberto Monje
Summary: The study assessed hard tissue dimensional changes following implant removal due to peri-implantitis, finding that simultaneous bone regeneration procedures and the use of a removal kit can significantly reduce the impact upon dimensional changes.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Mario Romandini, Jessica Berglundh, Jan Derks, Mariano Sanz, Tord Berglundh
Summary: The study aimed to evaluate the diagnostic accuracy of clinical and radiographic evaluations made at a single time point during follow-up. The bone levels observed at 9 years were highly accurate in identifying pronounced bone loss. In the absence of baseline documentation, a secondary case definition based on clinical findings provided the best overall diagnostic accuracy in identifying peri-implantitis cases.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Chemistry, Physical
Jae-Hong Lee, Eun-Hee Jung, Seong-Nyum Jeong
Summary: The study compared the outcomes of guided bone regeneration using L-shaped porcine block bone and L-shaped bovine block bone for peri-implant dehiscence defects. The results indicate that there was no significant difference between the two in clinical, radiographic, and volumetric outcomes.
Article
Dentistry, Oral Surgery & Medicine
Oded Heyman, Yael Horev, Gabriel Mizraji, Yaron Haviv, Lior Shapira, Asaf Wilensky
Summary: This study aimed to investigate the pathogenesis of peri-implantitis in mice and evaluate the efficacy of Resolvin D2 as a treatment modality. The results revealed that dental implants are susceptible to infection and associated with bone loss, but treatment with RvD2 can prevent the disease.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Yanhua Lan, Xiaoyuan Huang, Mingxing Fan, Huazhen Yu, Zhijian Xie, Yiqun Zhou
Summary: This study investigates the accuracy of cone beam computed tomography (CBCT) with a novel visualization method (NVM) for measuring peri-implant bone thickness in living patients. The NVM proved to be valid in ex vivo experiments and allowed for accurate visual assessment of implant dimensions. However, CBCT scans alone were found to be insufficient for surgical intervention, as they often underestimated thin peri-implant bones.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Jad Majzoub, Zhaozhao Chen, Islam Saleh, Houssam Askar, Hom-Lay Wang
Summary: The restorative design factors like restoration emergence angle and maintenance visit frequency significantly influenced the early progression of peri-implantitis. 66.3% of implants exhibited marginal bone loss within 1mm of the apical end of the internal screw, indicating a common location for peri-implant bone loss.
JOURNAL OF PERIODONTOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Xiaoxi Cui, Tyler Reason, Vanessa Pardi, Qiang Wu, Acela A. Martinez Luna
Summary: This retrospective study aimed to evaluate the correlation between crestal soft tissue thickness and hard tissue measurements on CBCT images, and to compare crestal soft tissue thickness among different patients and edentulous site groups. The results showed that more than half of the patients had crestal soft tissues at edentulous sites thicker than 2 mm, and there was a weak correlation between soft tissue thickness and hard tissue measurements.
Review
Dentistry, Oral Surgery & Medicine
Pedro Diaz, Esther Gonzalo, Luis J. Gil Villagra, Barbara Miegimolle, Maria J. Suarez
Summary: This systematic review estimates the overall prevalence of peri-implantitis and explores the impact of different study designs, function times, and use of probing depth on the prevalence rate. The results show that the prevalence of peri-implantitis is highly variable and the use of probing depth as a diagnostic criterion affects the prevalence data. It is important to identify diagnostic markers for more accurate disease classification.
Article
Dentistry, Oral Surgery & Medicine
Junying Li, Wael Att, Zhaozhao Chen, Luca Lepidi, Hom-Lay Wang, Tim Joda
Summary: This technique report presents a fully digital workflow for creating a virtual patient for complete-arch or complete-mouth implant rehabilitation using a prosthetic articulator-based implant rehabilitation (PAIR). The workflow involves using a custom gothic arch tracer and a 3-dimensional virtual facebow during cone beam computed tomography (CBCT) scan. The resulting PAIR virtual patient has accurate centric relation and vertical dimension of occlusion, and can be used for computer-aided implant planning and digital prosthetic design.
JOURNAL OF PROSTHETIC DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Bansari Shah, Monali Shah, Maria Geisinger, Muhammad H. A. Saleh, Mohamed Meghil, Hom-Lay Wang
Summary: This study demonstrated that scaling and root planing (SRP) can significantly reduce levels of CRP.
JOURNAL OF PERIODONTOLOGY
(2023)
Review
Cell & Tissue Engineering
Fangyu Zhu, Wenwen Liu, Pei Li, Han Zhao, Xuliang Deng, Hom-Lay Wang
Summary: This systematic review and network meta-analysis found that placing electric/magnetic materials in situ had more prominent effects than the electric/magnetic field on bone regeneration. Electrical materials with a zeta potential of -53 mV proved to be the most effective in increasing bone volume and bone mineral density. Magnetic materials with external magnetic fields showed the best results in increasing bone volume/tissue volume.
TISSUE ENGINEERING PART B-REVIEWS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Hamoun Sabri, Hom-Lay Wang
Summary: This study conducted a bibliometric analysis to identify the top 100 cited articles on peri-implantitis research. The findings revealed a focus on epidemiology rather than treatment strategies. The study also found no correlation between citation count and article age, indicating the continued impact of older articles. Overall, this research provides valuable insight into the characteristics and quality of peri-implantitis literature.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Guo-Hao Lin, Christine Tran, Karolina Brzyska, Joseph Y. Y. Kan, Hom-Lay Wang, Donald A. A. Curtis, Richard T. T. Kao
Summary: This retrospective study investigated the impact of vertical platform discrepancies on radiographic marginal bone loss in splinted and non-splinted adjacent implants. The results suggest that vertical platform discrepancies between adjacent implants are associated with a higher incidence of bone loss.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2023)
Article
Medicine, General & Internal
Paolo Carosi, Claudia Lorenzi, Riccardo Di Gianfilippo, Piero Papi, Andrea Laureti, Hom-Lay Wang, Claudio Arcuri
Summary: This study examined the outcomes of self-tapping implants placed in extraction sockets or healed edentulous ridges and immediately temporized. After one year, the implants showed high stability and survival rates, as well as favorable esthetic outcomes. The use of these implants with immediate temporization was safe and reliable.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Lorenzo Tavelli, Giovanni Zucchelli, Martina Stefanini, Giulio Rasperini, Hom-Lay Wang, Shayan Barootchi
Summary: Vertical soft tissue augmentation with implant submersion is an effective treatment for peri-implant soft tissue dehiscence with interproximal attachment loss in adjacent teeth, providing positive clinical, volumetric, and patient-reported outcomes.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Riccardo Di Gianfilippo, Chin-Wei Wang, Yuying Xie, Janet Kinney, James Sugai, William V. V. Giannobile, Hom-Lay Wang
Summary: This randomized clinical trial examined the changes in protein biomarker levels and bacterial profiles after surgical reconstructive therapy for peri-implantitis. The study also investigated the impact of adjunctive Er:YAG laser on protein biomarkers and microbial outcomes. The results showed that the surgical treatment significantly affected the levels of protein biomarkers and reduced the bacterial load.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Lorenzo Tavelli, Jad Majzoub, Frederic Kauffmann, Maria Vera Rodriguez, Leonardo Mancini, Hsun-Liang Chan, Oliver D. D. Kripfgans, William V. V. Giannobile, Hom-Lay Wang, Shayan Barootchi
Summary: This study compared the efficacy of coronally advanced flap (CAF) versus tunnel technique (TUN) in covering mid-facial peri-implant soft tissue dehiscences (PSTDs). The results showed that CAF + CTG yielded superior outcomes in terms of PSTD coverage, keratinized mucosa width, mucosal thickness, and aesthetic evaluation compared to TUN + CTG. Therefore, CAF + CTG treatment can achieve excellent repair of PSTDs.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Mitra Aliabouzar, Oliver D. Kripfgans, J. Brian Fowlkes, Mario L. Fabiilli
Summary: The development of phase-shift droplets has expanded the possibilities of ultrasound-based biomedical applications. Acoustic droplet vaporization (ADV), where the perfluorocarbon phase undergoes a phase transition to a gaseous state under sufficient acoustic pressures, has been extensively researched. This review covers experimental approaches, theoretical models, and recent advancements in tissue regeneration using ADV, as well as potential future applications in microrheology and pressure estimation.
ZEITSCHRIFT FUR MEDIZINISCHE PHYSIK
(2023)
Article
Acoustics
Hsi-Chien Yu, Oliver D. Kripfgans, Amanda B. Rodriguez, Ankita Samal, Carole Quesada, Liana P. Webber, John P. Mazzocco, I-Ching Wang, Jaeman Woo, Hsun-Liang Chan
Summary: This study investigated the biomechanical properties of porcine oral tissues using in vivo ultrasonography, comparing the differences between oral alveolar mucosa and gingival tissue in terms of compressional and tensile mechanical strain. The results showed significant differences in strain between the two types of tissues, with alveolar mucosa exhibiting greater longitudinal strain and slightly greater tensile strain than gingiva. These findings may have important clinical implications for the diagnosis and treatment of oral diseases.
JOURNAL OF ULTRASOUND IN MEDICINE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Carlo Barausse, Andrea Ravida, Lorenzo Bonifazi, Roberto Pistilli, Muhammad H. A. Saleh, Roberta Gasparro, Gilberto Sammartino, Hom-Lay Wang, Pietro Felice
Summary: This study investigated the use of extra-short (4-mm) implants to rehabilitate sites where regenerative procedures had failed, in order to avoid additional bone grafting. The results showed that out of 103 extra-short implants placed after failed regenerative procedures, 2 implants failed, resulting in a failure rate of 1.94% and an implant survival rate of 98.06%. The mean amount of marginal bone loss at 5 years post-loading was 0.32mm. Therefore, extra-short implants appear to be a good clinical option for managing reconstructive surgical failures, reducing surgical invasiveness and rehabilitation time.
INTERNATIONAL JOURNAL OF ORAL IMPLANTOLOGY
(2023)
Article
Physics, Applied
Mitra Aliabouzar, Bachir A. Abeid, Oliver D. Kripfgans, J. Brian Fowlkes, Jonathan B. Estrada, Mario L. Fabiilli
Summary: Phase-shift droplets generated a range of bioeffects via the mechanism of acoustic droplet vaporization (ADV), which could be applied in therapeutic and diagnostic ultrasound. This study visualized ADV-induced mechanics and sonoporation in fibrin-based hydrogels using ultra-high-speed microscopy, confocal microscopy, and focused ultrasound. The results showed that fibrin gels containing perfluoropentane (PFP) droplets exhibited significantly higher radial expansion, expansion velocity, induced strain, and displacement of tracer particles compared to gels containing perfluorohexane (PFH) or perfluorooctane (PFO) droplets. Cell membrane permeabilization was dependent on the distance between the droplet and cell, decreasing rapidly with increasing distance. The hyper-local region of influence by an ADV bubble correlated inversely with the boiling point of the phase-shift droplets. These findings provide insights for the development of optimal approaches for therapeutic applications of ADV.
APPLIED PHYSICS LETTERS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Martina Stefanini, Shayan Barootchi, Lorenzo Tavelli, Matteo Marzadori, Claudio Mazzotti, Ilham Mounssif, Matteo Sangiorgi, Hamoun Sabri, Hom-Lay Wang, Giovanni Zucchelli
Summary: This study introduces a difficulty score for evaluating the treatment of localized gingival recessions with the coronally advanced flap. The score showed good reproducibility among different operators. Further clinical intervention studies are needed to validate the clinical significance of the score.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Cho-Ying Lin, Pe-Yi Kuo, Meng-Yao Chiu, Zhao-Zhao Chen, Hom-Lay Wang
Summary: This study analyzed the tissue alterations around implants following soft tissue phenotype modification during implant uncovering surgery. The results showed that soft tissue phenotype modification resulted in favorable clinical outcomes, with stable mucosal tissue thickness and minimal recession. The pouch roll technique may influence the restorative design.
CLINICAL ORAL INVESTIGATIONS
(2023)
