Article
Chemistry, Multidisciplinary
Zhaofu Zhang, Yajing Zheng, Zilong Dou, Mengnan Gu, Mengxiao Sun, Jian Song, Nan Gao, Fengchao Cui, Yuyang Tian, Guangshan Zhu
Summary: Porous aromatic frameworks (PAFs) are versatile porous materials with promising functionality, but the synthesis of PAFs with desired properties is challenging. In this study, a multivariate inspired strategy was employed to successfully synthesize PAFs with highly porous and hierarchical structures. The PAFs obtained through this strategy exhibited both hierarchical structures and high specific surface areas. Furthermore, lipase was loaded onto one of the multivariate PAFs, showing high loading content and favorable catalytic activity and stability.
ACS CENTRAL SCIENCE
(2023)
Article
Agriculture, Multidisciplinary
Tong Li, Ruiguo Wang, Ruijie Yin, Hongyan Xu, Xiaoxu Han, Qiuling Du, Jie Cheng, Zhenyu Lin, Peilong Wang
Summary: A novel Zr(IV)-based metal-organic framework (MOF), named BUT-16, was synthesized and utilized for the extraction and enrichment of bisphenol compounds (BPs) in milk samples. The method showed a detection limit as low as 0.05 ng/mL and was successfully applied to the detection of BPs in real milk samples, yielding results consistent with previous methods.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Chemistry, Analytical
Yamei Han, Shan Wang, Yijie Liu, Ligai Bai, Hongyuan Yan, Haiyan Liu
Summary: By incorporating ionic liquid and MOF into a composite monolithic column, the surface area and adsorption capacity for tectochrysin were significantly increased. The method exhibited good linearity in the concentration range of 0.01-500 μg/mL, with a detection limit of 3.33 ng/mL.
ANALYTICAL METHODS
(2022)
Review
Chemistry, Inorganic & Nuclear
Mahnaz Najafi, Sara Abednatanzi, Parviz Gohari Derakhshandeh, Fariba Mollarasouli, Sonia Bahrani, Elham Sadati Behbahani, Pascal Van der Voort, Mehrorang Ghaedi
Summary: Environmental pollution caused by various industries has led to water contamination, posing a threat to human life worldwide. Therefore, it is crucial to explore affordable and efficient technologies for water purification. Metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) offer great potential in the field of water remediation. This review discusses the targeted design of MOFs and COFs, as well as key issues related to adjusting their structures and enhancing their stability for the removal of organic dyes through adsorption, catalysis, and extraction in water.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Nanoscience & Nanotechnology
Shao-Fei Wu, Bing-Zhi Yuan, Li-Wei Wang
Summary: Sorption working pairs have the potential to convert low-grade heat into cold energy or store thermal energy, making them future carbon-neutral materials. This Comment focuses on the advantages of metal-organic framework (MOF)-ammonia working pairs for adaptable thermal management in extreme climates and discusses strategies for designing MOFs with high stability and ammonia sorption capacity.
NATURE REVIEWS MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Cheng Ye, Meng He, Zhengdong Zhu, Xiaoyi Shi, Maofeng Zhang, Zhiyong Bao, Youju Huang, Changlong Jiang, Jianhua Li, Yucheng Wu
Summary: A novel dual-MOF-induced ZnO@Co3O4 heterostructure modified with AgNPs was designed and fabricated as a surface-enhanced Raman scattering (SERS) sensor for the sensitive identification and quantitative analysis of organophosphorus pesticides. The SERS sensor exhibited superior signal enhancement, reproducibility, and stability, and enabled rapid quantitative analysis of pesticide residues in real samples.
JOURNAL OF MATERIALS CHEMISTRY C
(2022)
Article
Chemistry, Applied
Xudong Qin, Weiting Yang, Weikang Yang, Yu Ma, Meiling Li, Chen Chen, Qinhe Pan
Summary: The study presents the synthesis of ZIF-90-ABOA with excellent uranium adsorption performance, demonstrating the potential enrichment of uranium from seawater and providing possibilities for nuclear energy development.
MICROPOROUS AND MESOPOROUS MATERIALS
(2021)
Editorial Material
Chemistry, Multidisciplinary
Gabrielle A. Leith, Corey R. Martin, Kyoung Chul Park, Natalia B. Shustoya
Summary: In the January issue of Chem, Farha and his co-workers demonstrated a breakthrough phenomenon by selectively de-interpenetrating uranium-containing metal-organic frameworks (MOFs), enabling the design and preparation of highly open MOF structures. This powerful concept offers a unique approach for synthesizing application-driven porous materials with accessible pore apertures.
Editorial Material
Chemistry, Multidisciplinary
Omar M. Yaghi
Summary: Understanding the mechanism of MOF crystal growth is crucial for their design. In this study, Deng and colleagues employ an optical method to visualize and track the crystal interface during MOF growth. They also derive a reaction kinetic equation for individual crystals of MOFs, which offers valuable guidance for MOF synthesis.
Article
Chemistry, Multidisciplinary
Yuan-Jun Tong, Lu-Dan Yu, Nan Li, Minhui Shen, Xiaoru Peng, Huangsheng Yang, Yu-Xin Ye, Fang Zhu, Janusz Pawliszyn, Jianqiao Xu, Gangfeng Ouyang
Summary: In this study, novel and highly luminescent suprastructures were synthesized via a two-step assembly method to incorporate LnCs in COFs. The obtained composites show high quantum yields and stable fluorescence performance under different pH conditions, demonstrating potential for sensing and light emitting applications.
Article
Chemistry, Physical
Sebastian J. Weishaeupl, Yang Cui, Simon N. Deger, Hamad Syed, Aleksandr Ovsianikov, Juergen Hauer, Alexander Poethig, Roland A. Fischer
Summary: Multiphoton absorption (MPA) is of great interest in modern materials research, and metal-organic frameworks and coordination polymers (CPs) are potential materials to overcome the limitations of commonly used chromophore molecules. This article reports the synthesis and characterization of three new highly MPA-active CPs, and demonstrates their large two-photon absorption cross-sections, which are among the highest reported for CPs to date.
CHEMISTRY OF MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Alessio Zuliani, M. Carmen Castillejos, Noureddine Khiar
Summary: Zirconium-based MOF PCN-222 has attracted attention for its regular porosity, tuneable pore size, versatile structure, and exceptional stability. However, traditional batch synthesis methods face limitations in productivity, scalability, and control over size and morphology. This study presents a paradigm shift to continuous flow synthesis, which enables efficient production of high-quality PCN-222 with improved resource efficiency, scalability, and safety. The integration of ultrasound-assisted technique and greener solvents further enhances the sustainability and potential applications of PCN-222.
Review
Chemistry, Analytical
Igor E. Uflyand, Vladimir A. Zhinzhilo, Victoria O. Nikolaevskaya, Boris Kharisov, Cesar M. Oliva Gonzalez, Oxana Kharissova
Summary: This review summarizes the recent applications of metal-organic frameworks (MOFs) in solid phase extraction (SPE) of organic dyes, focusing on the development of MOF performance enhancement strategies and their application in specific dye separation and real object analysis. Further research directions in using MOF in SPE of organic dyes are outlined for future exploration.
MICROCHEMICAL JOURNAL
(2021)
Review
Chemistry, Physical
Yuying Shan, Liyu Chen, Huan Pang, Qiang Xu
Summary: Hybrid frameworks based on MOFs demonstrate excellent properties with complex compositions and well-designed structures, surpassing traditional single framework materials.The high chemical tunability and diversity of these new materials offer great potential for both synthetic approaches and a wide range of applications. Opportunities and challenges for MOF-based hybrid frameworks are discussed, highlighting their promising prospects in various fields.
Article
Chemistry, Inorganic & Nuclear
Meiying Liu, Yadong Tian, Zhiliang Liu
Summary: A convenient strategy of doping metal ions into the framework nodes of MOFs is adopted to enhance ferroelectric performance. The doped Co-Gallate materials show obviously improved ferroelectric properties compared with the parent MOF, with enhanced remanent polarization. The increase in ferroelectric behavior is related to the difference in ionic radius between Co2+ ions and the metal ions.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Analytical
Shu-Ting Xu, Cheng Yang, Xiu-Ping Yan
Summary: Cell cycle discrimination is crucial for studying cellular heterogeneity in single-cell analysis based on organic mass spectrometry. A robust protocol using three small molecular indicators was developed to discriminate single cells at different cycle stages in real time. This protocol successfully discriminated single cells at G0/G1, S, and G2/M stages and revealed significant heterogeneity in amino acids, nucleotides, energy metabolic intermediates, and phospholipids among cells at different cycle stages.
ANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Analytical
Shu-Ting Xu, Xiu-Ping Yan, Hai-Long Qian
ANALYTICAL CHEMISTRY
(2023)
Article
Engineering, Environmental
Yi-Xuan Wang, Yan-Ping Bi, Yuan-Yuan Cui, Cheng-Xiong Yang
Summary: By synthesizing a novel type of crown ether (CE)-based microporous organic networks (MONs), efficient and rapid adsorption and removal of specific environmental priority pollutants are achieved, while also addressing the stability issues of crown ether in most solvents. This study highlights the potential of CE-based MONs in contaminant elimination.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Chemistry, Analytical
Hao-Fei Sun, Yuan-Yuan Cui, Chang-Qing Zhen, Cheng-Xiong Yang
Summary: This study describes the fabrication of core-shell MON-2COOH@SiO2 microspheres via a monomer-mediated method for reversed-phase liquid chromatography (RPLC)/hydrophilic interaction liquid chromatography (HILIC) mixed-mode chromatography. The MON-2COOH@SiO2 column showed high resolution and selectivity for separating hydrophobic and hydrophilic probes, as well as pharmaceutical compounds. It also offered better separation performance compared to commercial C18 and pristine SiO2 columns.
Article
Materials Science, Composites
Dan Wang, Yidong Peng, Jiancheng Dong, Lei Pu, Kangqi Chang, Xiu-Ping Yan, Le Li, Yunpeng Huang, Tianxi Liu
Summary: In this study, polyimide aerogel fibers were fabricated using an in-situ polymerization method and wet-spinning technique with Ti3C2Tx flakes as pore-generating agents. These aerogel fibers showed enhanced mechanical properties, large specific surface area, excellent flame resistance, and remarkable thermal insulation performance. They can be woven into flexible textiles for practical thermal regulating applications.
COMPOSITES COMMUNICATIONS
(2023)
Article
Engineering, Environmental
Yaqiang Duan, Pengwu Xu, Tianxi Liu, Zicheng Wang, Xiuping Yan, Weijun Yang, Deyu Niu, Piming Ma
Summary: Designing a sandwich-like heterostructure of PDMS/SiO2@MXene composites with a floatable interlayer was achieved by regulating the affinity of mixed solvents and SiO2@MXene. The composites exhibited superior EMI shielding effectiveness, stable mechanical property, and wide temperature window in application.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Environmental
Shuyan Wu, Shichao Cai, Fengyang Qin, Feng He, Tianxi Liu, Xiuping Yan, Zhenyu Wang
Summary: Ball milling is effective in activating and reducing the size of microscale zero valent iron (mZVI) and sulfidating mZVI mechanochemically. However, there are differences in the interaction between chlorinated ethenes (CEs) and ball milled mZVI (mZVIbm) and mechanochemically sulfidated mZVI (S-mZVIbm) that are not well understood. This study found that simple ball milling exposed active Fe0 sites, while mechanochemical sulfidation decreased Fe0 sites and increased S2 sites. The sulfidation process enhanced the reactivity of TCE dechlorination the most, followed by PCE and 1,1-DCE, but reduced the reactivity of trans-DCE, cis-DCE, and VC compared to simple ball milling. Sulfidation also improved the electron efficiency of CE dechlorination, except for cis-DCE and VC. The kSA of cis-DCE, VC, and trans-DCE dechlorination positively correlated with the sulfide content.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Chemistry, Analytical
Hui-Ping Yu, Hu-Bo Ren, Yuan-Yuan Cui, Cheng-Xiong Yang
Summary: This study presents the room-temperature fabrication of a novel dual-functionalized magnetic microporous organic network (MMON-B) for efficient extraction of vanillin additives from complex food samples, facilitating subsequent high-performance liquid chromatography analysis. The results demonstrate the feasibility of using a room-temperature method for synthesizing dual-functionalized MMONs, potentially advancing their application in the magnetic solid-phase extraction of trace targets from complex matrices.
Article
Nanoscience & Nanotechnology
Xu Zhao, Kang-Kang Zhang, Li-Jian Chen, Zhen-Yu Wang, Xiu-Ping Yan
Summary: We design and synthesize an acid-activated near-infrared probe to construct an intelligent theranostic nanoplatform for tumor-targeting image-guided photothermal and photodynamic therapy. The nanoplatform combines precise tumor targeting ability, specific imaging with a high signal-to-noise ratio, and excellent in vivo antitumor activity.
ACS APPLIED NANO MATERIALS
(2023)
Article
Engineering, Manufacturing
Minhao Guo, Yufan Zhang, Chun Huang, Xu Zhao, Xiu-Ping Yan, Yunpeng Huang, Le Li, Tianxi Liu
Summary: This study successfully developed a novel shape memory polyimide aerogel composite with a high programming temperature and excellent shape recovery capability. By regulating molecular interactions and pore structures, the desired thermo-mechanical performances were achieved, showing great potential for widespread applications in harsh environments.
COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING
(2023)
Article
Chemistry, Applied
Qing Huang, Lixia Yan, Haodong Wei, Xingjian Ye, Wenlong Wang, Cheng Yang, Xiu-Ping Yan, Yi Zhang
Summary: Heat treatment and the use of additives in food processing can introduce nanomaterials, which have raised concerns due to the lack of toxicological investigation and market standards. This study focused on the structural properties and cytotoxicity of fluorescent carbon nanoparticles (FCNPs) in fried bamboo charcoal peanuts. It was found that FCNPs extracted from charcoal shells and peanut kernels had different particle sizes and water solubility properties. Furthermore, the cellular endocytosis and toxic effects of FCNPs were explored, with charcoal-shell FCNPs showing slightly higher toxicity compared to peanut kernel FCNPs.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Engineering, Environmental
Li-Hong Su, Hai -Long Qian, Cheng Yang, Chuanxi Wang, Zhenyu Wang, Xiu- Ping Yan
Summary: This study presents a facile surface imprinting approach using dopamine to generate imprinted cavities on the surface of irreversible COF for efficient extraction of fluoroquinolones (FQs) in food samples. The resulting MI-COF exhibited exceptional adsorption capacity, with a 2.2-fold enhancement compared to nonimprinted COF. Furthermore, MI-COF was successfully employed as an adsorbent coupled with HPLC for the simultaneous determination of enrofloxacin, norfloxacin, and ciprofloxacin, showing low limits of detection, high precision, and satisfactory recoveries in food samples.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Li-Ya Wang, Li-Xia Yan, Xu Zhao, Li-Jian Chen, Xiu-Ping Yan
Summary: This study developed a pH-responsive theragnostic nanoplatform for targeted imaging and local drug release at the bacterial infection site. The nanoplatform consists of core-shell structure with persistent luminescence nanoparticles (PLNPs) as the core and zeolitic imidazolate framework-8 (ZIF-8) as the shell loaded with antibiotics. The nanoparticles were further conjugated with folic acid (FA) to achieve autofluorescence-free targeted imaging at the infection site. The acidic microenvironment at the bacterial infection site enables ZIF-8 to decompose and release drugs, improving the efficacy of bacterial infection treatment.
Article
Nanoscience & Nanotechnology
Xu Zhao, Ming-Yue Yin, Tian-Yue Gu, Xue-Mei Gao, Li-Jian Chen, Zhen-Yu Wang, Xiu-Ping Yan
Summary: This study reported a pH-/H2O2-activated and self-luminous nanosphere for intelligent bacteria-targeting and self-reported imaging-guided precision phototherapy sterilization. The nanosphere, formed by self-assembly of CMC-PC-N with CPPO, can rapidly release CPPO in the bacterial acidic microenvironment. The released CPPO can activate the fluorescence of the porphyrin for self-report imaging and achieve efficient phototherapy sterilization under external irradiation.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Analytical
Xue-Mei Gao, Tian-Yue Gu, Ke-Lin Chen, Xu Zhao, Xiu-Ping Yan
Summary: In this study, an intelligent luminescence ratiometric sensor based on ultra-small dual-emissive PLNP is reported for precise tumor-targeted imaging. The PLNP-Mal@Cy5.5 sensor can achieve long-term retention and specificity imaging by detecting the change of I-708/I-501.
ANALYSIS & SENSING
(2023)
Correction
Biochemical Research Methods
Yong Wang, Suhua Yu, Rui Li, Jing Wan, Yuheng Wang, Zongli Huo, Chunyong Wu, Li Mi, Songqin Liu
JOURNAL OF CHROMATOGRAPHY A
(2024)
Review
Biochemical Research Methods
Israel D. Souza, Maria Eugenia C. Queiroz
Summary: Organic-silica hybrid monolithic materials have gained significant attention in separation science and sample preparation due to their unique properties. This review summarizes the characteristics, current status, and recent developments of these materials, as well as discusses synthesis methods, characterization techniques, and strategies for improving extraction efficiency in various applications.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Bhagwat Upreti, Bhanu Prasad Vempatapu, Jagdish Kumar, Pankaj K. Kanaujia
Summary: Lubricating oils are essential for the effective performance of internal combustion engines. This study presents a new HPLC method for determining additives in finished lubricating oils and polar substances in used engine oils.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zongqing Huang, Haoju Hua, Xiuzhen Du, Zipeng Zhen, Wei Zhao, Jun Feng, Ji-an Li
Summary: This study successfully isolated VHHs against the SUMO protein for the first time using biopanning of an immune camelid nanobody library. The VHHs were coupled to agarose resins to form affinity chromatography resins, allowing for one-step purification of various SUMO fusions.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Xueting Qiu, Xuben Hou, Yue Yang, Hao Fang, Fei Cui, Xinying Yang
Summary: In this study, a new method based on electrophoretically mediated microanalysis was developed for the investigation of PTPRO enzymatic activity. The method was successfully used to determine the kinetics of PTPRO and the inhibitory concentration of PTPRO inhibitors. The method exhibited improved accuracy and reduced consumption compared to traditional methods.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Feifei Luo, Mengmeng Hao, Lei Zhang, Yangguo Xie, Wei Hou, Hongya Wang, Zhongli Zhang
Summary: In this study, a comprehensive screening and structure elucidation of 23 nonvolatile organic compounds (NVOCs) in two antibody drugs was conducted. Seven previously unreported compounds were identified. A quantitative method with high sensitivity, accuracy, and precision was developed for evaluating the safety of NVOCs in drug products.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zuzana Vosahlova, Kveta Kalfkova, Martin Gilar, Jakub Szymarek, Maria Mazurkiewicz-Beldzinska, Sylwia Studzi
Summary: A hydrophilic interaction liquid chromatography method was developed for the separation and identification of oligonucleotide impurities and metabolites, and successfully applied to the analysis of serum samples from Spinraza-treated patients.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Aswanidevi Kongasseri, Thirumalai Madhesan, Sangeetha Krishna Kumar, Sushmitha Pedugu Sivaraman, Suchashrita Mitra, Pitchaiah Kancharlapalli Chinaraga, C. V. S. Brahmmananda Rao, Sivaraman Nagarajan, Prabhakaran Deivasigamani, Akhila Maheswari Mohan
Summary: This study focuses on the sequential separation of trivalent lanthanides using modified C-18 silica-packed supports and reversed-phase HPLC technique. By tuning the column modifiers and separation parameters, the researchers achieved systematic separation of Ln(3+). The results showed that the choice of column modifiers and fine-tuning of the modification procedure were crucial for achieving excellent separation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Raquel Perez-Robles, Szabolcs Fekete, Robert Kormany, Natalia Navas, Davy Guillarme
Summary: There is a mismatch between the sample diluent and the mobile phase in HILIC analysis, leading to analyte breakthrough and peak distortion. Adding a weak solvent for pre-injection can effectively prevent these issues and improve sensitivity.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oleg Pokrovskiy, Irina Rostovschikova, Konstantin Ustinovich, Ilya Voronov, Dmitry Kosyakov
Summary: A chromatography-like propagation of water through the material bed was observed during supercritical fluid extraction of aroma plants with high moisture content, which could be significant for modeling the kinetics of supercritical fluid extraction of non-volatile compounds.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Yasar Kemal Recepoglu, Ozguer Arar, Asli Yuksel
Summary: Biosorption using phosphorylated hazelnut shell waste (FHS) is a promising method for lithium removal and recovery. This study investigated the performance of a continuous-flow packed-bed column system using FHS for ultra-low level lithium removal. The results showed that the lihium biosorption capacity of the FHS column was unaffected by the bed height, but decreased with increasing flow rate.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Jian Sun, Zheheng Zheng, Zixiao Jia, Jiabin Wang, Xucong Lin
Summary: In this study, an ionic covalent organic framework (iCOF) surface grafting monolithic sorbent was prepared for in-tube solid-phase microextraction (SPME) of aristolochic acids (AAs) in various samples. The density of quaternary ammonium ions in the iCOF was modulated for enhanced adsorption of AAs. The iCOF surface grafting monolithic sorbent was confirmed by different means. Several operating conditions were optimized to develop the online in-tube SPME-HPLC method, which showed good linearity, low limits of detection, and high recoveries for AAs in serum samples. This study presents a feasible approach for the application of COF-based monolithic sorbents in sample preparation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zeng Wen, Ruihan Peng, Die Gao, Jing Lin, Jia Zeng, Zhou Li, Famin Ke, Zhining Xia, Dandan Wang
Summary: A chitosan-alginate sponge with multiple cross-linking networks was developed for adsorption and enrichment of anionic dyes from food samples. The sponge showed better three-dimensional network structure, mechanical behavior, and stability compared to pure chitosan and alginate sponges. The adsorption performance and selectivity of the sponge were systematically studied, and it maintained high adsorption capacity and selectivity for anionic dyes. The sponge also showed satisfactory reusability and was successfully combined with high-performance liquid chromatography for the enrichment and detection of anionic dyes in candy and cocktail samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Hairong Zhang, Xiaojuan Jiang, Dandan Zhang, Yuexin Yang, Qiang Xie, Caisheng Wu
Summary: Analysis of in vivo exposure to traditional Chinese medicine using mass spectrometry is helpful for identifying effective ingredients and developing new drugs. This study focused on Forsythia suspensa (Lian Qiao) and used metabolomics technology to explore its in vivo exposure. By comparing the differences before and after administration, a complete set of nontargeted analysis strategies for TCM exposure was established. The study identified 393 Lian Qiao-related chemical components in mice after administration, including prototypes and metabolites. This study provides a reference for research on the active ingredients of Lian Qiao in vivo.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oscar Castejon-Musulen, Ricardo Lopez, Ignacio Ontan, Vicente Ferreira
Summary: A quantitative analytical method was developed and validated in this study to determine the concentrations of 81 aroma-relevant wine volatiles. The method utilizes stir bar sorptive extraction and multidimensional gas chromatography with flame ionization detector or mass spectrometer. The method demonstrated good linearity, reproducibility, and recovery, and was successfully applied to analyze 20 wine samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)