Protective effects of sulforaphane in experimental vascular cognitive impairment: Contribution of the Nrf2 pathway

Neuropathological diagnosis of vascular cognitive impairment and vascular dementia with implications for Alzheimer’s disease

(2016) Raj N. Kalaria   ACTA NEUROPATHOLOGICA

Vascular cognitive impairment: Modeling a critical neurologic disease in vitro and in vivo

(2016) Alex M. Helman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Science of Vascular Contributions to Cognitive Impairment and Dementia (VCID): A Framework for Advancing Research Priorities in the Cerebrovascular Biology of Cognitive Decline

(2016) Roderick A. Corriveau et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Gradual cerebral hypoperfusion in spontaneously hypertensive rats induces slowly evolving white matter abnormalities and impairs working memory

(2016) Akihiro Kitamura et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Vascular cognitive impairment: Biomarkers in diagnosis and molecular targets in therapy

(2016) Gary A Rosenberg   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Anti-inflammatory activity of Barleria lupulina: Identification of active compounds that activate the Nrf2 cell defense pathway, organize cortical actin, reduce stress fibers, and improve cell junctions in microvascular endothelial cells

(2016) Donald R. Senger et al.   JOURNAL OF ETHNOPHARMACOLOGY

Prevention of Hippocampal Neuronal Damage and Cognitive Function Deficits in Vascular Dementia by Dextromethorphan

(2016) Xiaofeng Xu et al.   MOLECULAR NEUROBIOLOGY

Omega-3 polyunsaturated fatty acids mitigate blood–brain barrier disruption after hypoxic–ischemic brain injury

(2016) Wenting Zhang et al.   NEUROBIOLOGY OF DISEASE

Vascular Contributions to Cognitive Impairment and Dementia

(2016) Jeremy B. Madigan et al.   STROKE

Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury

(2016) Yejie Shi et al.   Nature Communications

Rodent Models of Vascular Cognitive Impairment

(2016) Yi Yang et al.   Translational Stroke Research

Acupuncture ameliorates cognitive impairment and hippocampus neuronal loss in experimental vascular dementia through Nrf2-mediated antioxidant response

(2015) Xue-Rui Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

The neuropathology and cerebrovascular mechanisms of dementia

(2015) Limor Raz et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

CNS myelin sheath is stochastically built by homotypic fusion of myelin membranes within the bounds of an oligodendrocyte process

(2015) Sara Szuchet et al.   JOURNAL OF STRUCTURAL BIOLOGY

Inhibition of Gli1 mobilizes endogenous neural stem cells for remyelination

(2015) Jayshree Samanta et al.   NATURE

Blood-brain barrier damage in vascular dementia

(2015) Masaki Ueno et al.   NEUROPATHOLOGY

Interaction between hypertension and cerebral hypoperfusion in the development of cognitive dysfunction and white matter pathology in rats

(2015) J.Y. Choi et al.   NEUROSCIENCE

Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation

(2015) Yang Bai et al.   Oxidative Medicine and Cellular Longevity

Transcription factors Hsf1 and Nrf2 engage in crosstalk for cytoprotection

(2015) Sharadha Dayalan Naidu et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Altered Nrf2 Signaling Mediates Hypoglycemia-Induced Blood–Brain Barrier Endothelial Dysfunction In Vitro

(2015) Ravi K. Sajja et al.   PLoS One

Galectin-1-secreting neural stem cells elicit long-term neuroprotection against ischemic brain injury

(2015) Jiayin Wang et al.   Scientific Reports

Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue

(2014) Nicolas Snaidero et al.   CELL

Omega-3 Fatty Acids Protect the Brain against Ischemic Injury by Activating Nrf2 and Upregulating Heme Oxygenase 1

(2014) M. Zhang et al.   JOURNAL OF NEUROSCIENCE

The prevalence of dementia in urban and rural areas of China

(2013) Jianping Jia et al.   Alzheimers & Dementia

The Heme Oxygenase System Selectively Suppresses the Proinflammatory Macrophage M1 Phenotype and Potentiates Insulin Signaling in Spontaneously Hypertensive Rats

(2013) Joseph Fomusi Ndisang et al.   AMERICAN JOURNAL OF HYPERTENSION

Sulforaphane ameliorates the development of experimental autoimmune encephalomyelitis by antagonizing oxidative stress and Th17-related inflammation in mice

(2013) Bin Li et al.   EXPERIMENTAL NEUROLOGY

Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood–brain barrier disruption and neurological deficits in stroke

(2013) Alessio Alfieri et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vascular Aspects of Cognitive Impairment and Dementia

(2013) Maximilian Wiesmann et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Vascular cognitive impairment and Alzheimer’s disease: role of cerebral hypoperfusion and oxidative stress

(2013) Hyun Ah Kim et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Deletion of Nrf2 impairs functional recovery, reduces clearance of myelin debris and decreases axonal remyelination after peripheral nerve injury

(2013) Linxia Zhang et al.   NEUROBIOLOGY OF DISEASE

The Pathobiology of Vascular Dementia

(2013) Costantino Iadecola   NEURON

Monetary Costs of Dementia in the United States

(2013) Michael D. Hurd et al.   NEW ENGLAND JOURNAL OF MEDICINE

Roles of White Matter in Central Nervous System Pathophysiologies

(2012) Carlos Matute et al.   ASN Neuro

Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions

(2012) Tim Clarner et al.   GLIA

Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection

(2012) Meijuan Zhang et al.   PROGRESS IN NEUROBIOLOGY

Myelin Loss Associated With Neuroinflammation in Hypertensive Rats

(2012) Fakhreya Y. Jalal et al.   STROKE

Cerebrovascular Disease and Mechanisms of Cognitive Impairment

(2012) Raj N. Kalaria   STROKE

Pharmacological Induction of Heme Oxygenase-1 by a Triterpenoid Protects Neurons Against Ischemic Injury

(2012) Feng Zhang et al.   STROKE

Sulforaphane protects primary cultures of cortical neurons against injury induced by oxygen-glucose deprivation/reoxygenation via antiapoptosis

(2012) Xuemei Wu et al.   Neuroscience Bulletin

Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts

(2011) Yoko Okamoto et al.   ACTA NEUROPATHOLOGICA

Cerebrovascular hemodynamics in Alzheimer's disease and vascular dementia: A meta-analysis of transcranial Doppler studies

(2011) Behnam Sabayan et al.   AGEING RESEARCH REVIEWS

Cellular Mechanisms of Neurovascular Damage and Repair After Stroke

(2011) Ken Arai et al.   JOURNAL OF CHILD NEUROLOGY

Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis

(2011) Jason G Weinger et al.   Journal of Neuroinflammation

Metabolism and Tissue Distribution of Sulforaphane in Nrf2 Knockout and Wild-Type Mice

(2011) John D. Clarke et al.   PHARMACEUTICAL RESEARCH

Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation

(2011) K.-i. Fujita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

When NRF2 Talks, Who's Listening?

(2010) Nobunao Wakabayashi et al.   ANTIOXIDANTS & REDOX SIGNALING

Sulforaphane protects brains against hypoxic–ischemic injury through induction of Nrf2-dependent phase 2 enzyme

(2010) Zhang Ping et al.   BRAIN RESEARCH

Heme Oxygenase-1 expression in M-CSF-polarized M2 macrophages contributes to LPS-induced IL-10 release

(2010) Elena Sierra-Filardi et al.   IMMUNOBIOLOGY

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of Heme Oxygenase-1 Is Neuroprotective in a Model of Permanent Middle Cerebral Artery Occlusion in Transgenic Mice

(2010) Nariman Panahian et al.   JOURNAL OF NEUROCHEMISTRY

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

(2010) Robert D. Bell et al.   NEURON

Vascular basis for brain degeneration: faltering controls and risk factors for dementia

(2010) Raj N Kalaria   NUTRITION REVIEWS

Gaussia luciferase reporter assay for monitoring biological processes in culture and in vivo

(2009) Bakhos A Tannous   Nature Protocols

What Is the Optimal Value of the g-Ratio for Myelinated Fibers in the Rat CNS? A Theoretical Approach

(2009) Taylor Chomiak et al.   PLoS One

Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-element

(2008) Edward A. Felinski et al.   EXPERIMENTAL EYE RESEARCH

Morphologic diagnosis of “vascular dementia” — A critical update

(2008) Kurt A. Jellinger   JOURNAL OF THE NEUROLOGICAL SCIENCES

Cloning and characterization of the murine claudin-5 promoter

(2008) Malgorzata Burek et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The coming acceleration of global population ageing

(2008) Wolfgang Lutz et al.   NATURE