Neuronal glucose metabolism is impaired while astrocytic TCA cycling is unaffected at symptomatic stages in the hSOD1G93A mouse model of amyotrophic lateral sclerosis

Altered Metabolic Profiles Associate with Toxicity in SOD1G93A Astrocyte-Neuron Co-Cultures

(2017) Gabriel N. Valbuena et al.   Scientific Reports

Hyperactive somatostatin interneurons contribute to excitotoxicity in neurodegenerative disorders

(2016) Wen Zhang et al.   NATURE NEUROSCIENCE

Interactions in the Metabolism of Glutamate and the Branched-Chain Amino Acids and Ketoacids in the CNS

(2016) Marc Yudkoff   NEUROCHEMICAL RESEARCH

Alternative Fuels in Epilepsy and Amyotrophic Lateral Sclerosis

(2016) Tesfaye W. Tefera et al.   NEUROCHEMICAL RESEARCH

Triheptanoin Protects Motor Neurons and Delays the Onset of Motor Symptoms in a Mouse Model of Amyotrophic Lateral Sclerosis

(2016) Tesfaye W. Tefera et al.   PLoS One

Metabolomic Analysis Reveals Increased Aerobic Glycolysis and Amino Acid Deficit in a Cellular Model of Amyotrophic Lateral Sclerosis

(2015) Gabriel N. Valbuena et al.   MOLECULAR NEUROBIOLOGY

Disruption of TCA Cycle and Glutamate Metabolism Identified by Metabolomics in an In Vitro Model of Amyotrophic Lateral Sclerosis

(2015) Charlotte Veyrat-Durebex et al.   MOLECULAR NEUROBIOLOGY

The anticonvulsant actions of carisbamate associate with alterations in astrocyte glutamine metabolism in the lithium-pilocarpine epilepsy model

(2014) Mussie Ghezu Hadera et al.   JOURNAL OF NEUROCHEMISTRY

Glutamate synthesis has to be matched by its degradation - where do all the carbons go?

(2014) Ursula Sonnewald   JOURNAL OF NEUROCHEMISTRY

Altered Astrocyte–Neuronal Interactions After Hypoxia-Ischemia in the Neonatal Brain in Female and Male Rats

(2014) Tora Sund Morken et al.   STROKE

Weight loss, dysphagia and supplement intake in patients with amyotrophic lateral sclerosis (ALS): impact on quality of life and therapeutic options

(2013) Sonja Körner et al.   BMC Neurology

Dysregulation of the complement cascade in the hSOD1G93A transgenic mouse model of amyotrophic lateral sclerosis

(2013) John D Lee et al.   Journal of Neuroinflammation

Superoxide dismutase 1 mutation in a cellular model of amyotrophic lateral sclerosis shifts energy generation from oxidative phosphorylation to glycolysis

(2013) Scott P. Allen et al.   NEUROBIOLOGY OF AGING

Metabolic signatures of amyotrophic lateral sclerosis reveal insights into disease pathogenesis

(2013) J. C. Dodge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Imbalance Between Excitatory and Inhibitory Neurotransmitters in Amyotrophic Lateral Sclerosis Revealed by Use of 3-T Proton Magnetic Resonance Spectroscopy

(2013) Bradley R. Foerster et al.   JAMA Neurology

The relationship between Bayesian motor unit number estimation and histological measurements of motor neurons in wild-type and SOD1G93A mice

(2012) S.T. Ngo et al.   CLINICAL NEUROPHYSIOLOGY

Decreased motor cortex  -aminobutyric acid in amyotrophic lateral sclerosis

(2012) B. R. Foerster et al.   NEUROLOGY

Modulation of Astrocytic Mitochondrial Function by Dichloroacetate Improves Survival and Motor Performance in Inherited Amyotrophic Lateral Sclerosis

(2012) Ernesto Miquel et al.   PLoS One

Dysregulation of astrocyte–motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis

(2011) Laura Ferraiuolo et al.   BRAIN

Brain hypermetabolism in amyotrophic lateral sclerosis: a FDG PET study in ALS of spinal and bulbar onset

(2011) Angelina Cistaro et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Early and Progressive Impairment of Spinal Blood Flow—Glucose Metabolism Coupling in Motor Neuron Degeneration of ALS Model Mice

(2011) Kazunori Miyazaki et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Glutamate and glutathione interplay in a motor neuronal model of amyotrophic lateral sclerosis reveals altered energy metabolism

(2011) Giuseppina D'Alessandro et al.   NEUROBIOLOGY OF DISEASE

Reduced GABAergic Inhibition Explains Cortical Hyperexcitability in the Wobbler Mouse Model of ALS

(2010) Jose Luis Nieto-Gonzalez et al.   CEREBRAL CORTEX

Relationship between neuropathology and disease progression in the SOD1G93A ALS mouse

(2010) Wendy W. Yang et al.   EXPERIMENTAL NEUROLOGY

Transcriptional Profiling in the Lumbar Spinal Cord of a Mouse Model of Amyotrophic Lateral Sclerosis: A Role for Wild-Type Superoxide Dismutase 1 in Sporadic Disease?

(2010) Antonello D’Arrigo et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Energy metabolism in amyotrophic lateral sclerosis

(2010) Luc Dupuis et al.   LANCET NEUROLOGY

Impaired blood–brain and blood–spinal cord barriers in mutant SOD1-linked ALS rat

(2009) Charles Nicaise et al.   BRAIN RESEARCH

Characterization of 14C-acetate uptake in cultured rat astrocytes

(2008) Rie Hosoi et al.   BRAIN RESEARCH

Crosstalk between astrocytes and motor neurons: What is the message?

(2008) L. Van Den Bosch et al.   EXPERIMENTAL NEUROLOGY

Neonatal Neuronal Circuitry Shows Hyperexcitable Disturbance in a Mouse Model of the Adult-Onset Neurodegenerative Disease Amyotrophic Lateral Sclerosis

(2008) B. van Zundert et al.   JOURNAL OF NEUROSCIENCE

MnSOD deficiency has a differential effect on disease progression in two different ALS mutant mouse models

(2008) Florian L. Muller et al.   MUSCLE & NERVE