Curcumin on the “flying carpets” to modulate different signal transduction cascades in cancers: Next-generation approach to bridge translational gaps

Curcumin Derivative Epigenetically Reactivates Nrf2 Antioxidative Stress Signaling in Mouse Prostate Cancer TRAMP C1 Cells

(2018) Wenji Li et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Curcumin Suppresses In Vitro Proliferation and Invasion of Human Prostate Cancer Stem Cells by Modulating DLK1-DIO3 Imprinted Gene Cluster MicroRNAs

(2018) Hu Zhang et al.   Genetic Testing and Molecular Biomarkers

pH-sensitive polymeric nanoparticles of mPEG-PLGA-PGlu with hybrid core for simultaneous encapsulation of curcumin and doxorubicin to kill the heterogeneous tumour cells in breast cancer

(2018) Jian-Dong Yuan et al.   Artificial Cells Nanomedicine and Biotechnology

Induction of apoptosis in HeLa cancer cells by an ultrasonic-mediated synthesis of curcumin-loaded chitosan–alginate–STPP nanoparticles

(2017) Fatemeh Ahmadi et al.   International Journal of Nanomedicine

Exploring recent developments to improve antioxidant, anti-inflammatory and antimicrobial efficacy of curcumin: A review of new trends and future perspectives

(2017) Zahid Hussain et al.   Materials Science & Engineering C-Materials for Biological Applications

Curcumin analog L48H37 induces apoptosis through ROS-mediated endoplasmic reticulum stress and STAT3 pathways in human lung cancer cells

(2017) Chen Feng et al.   MOLECULAR CARCINOGENESIS

Curcumin Nanotechnologies and Its Anticancer Activity

(2017) Parasuraman Aiya Subramani et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways

(2017) Jian-Yun Zhu et al.   PHYTOTHERAPY RESEARCH

Reverse effect of curcumin on CDDP-induced drug-resistance via Keap1/p62-Nrf2 signaling in A549/CDDP cell

(2017) Jie Shen et al.   Asian Pacific Journal of Tropical Medicine

Curcumin reversed chronic tobacco smoke exposure induced urocystic EMT and acquisition of cancer stem cells properties via Wnt/β-catenin

(2017) Zhaofeng Liang et al.   Cell Death & Disease

Folic acid conjugation improves the bioavailability and chemosensitizing efficacy of curcumin-encapsulated PLGA-PEG nanoparticles towards paclitaxel chemotherapy

(2017) Arun Kumar T. Thulasidasan et al.   Oncotarget

Curcumin Inhibits Gastric Carcinoma Cell Growth and Induces Apoptosis by Suppressing the Wnt/β-Catenin Signaling Pathway

(2017) Ruzhen Zheng et al.   MEDICAL SCIENCE MONITOR

Combination curcumin and (−)-epigallocatechin-3-gallate inhibits colorectal carcinoma microenvironment-induced angiogenesis by JAK/STAT3/IL-8 pathway

(2017) G Jin et al.   Oncogenesis

NOX4-mediated ROS production induces apoptotic cell death via down-regulation of c-FLIP and Mcl-1 expression in combined treatment with thioridazine and curcumin

(2017) Seung Un Seo et al.   Redox Biology

Correction: Long-Circulating Curcumin-Loaded Liposome Formulations with High Incorporation Efficiency, Stability and Anticancer Activity towards Pancreatic Adenocarcinoma Cell Lines In Vitro

(2017) Mohamed Mahmud et al.   PLoS One

Exploration of inhibitory mechanisms of curcumin in lung cancer metastasis using a miRNA- transcription factor-target gene network

(2017) De-min Jiao et al.   PLoS One

Discovery of monocarbonyl curcumin-BTP hybrids as STAT3 inhibitors for drug-sensitive and drug-resistant breast cancer therapy

(2017) Wenda Zhang et al.   Scientific Reports

Rational Design of Multifunctional Dendritic Mesoporous Silica Nanoparticles to Load Curcumin and Enhance Efficacy for Breast Cancer Therapy

(2016) Jiao Wang et al.   ACS Applied Materials & Interfaces

Curcumin induces G0/G1 arrest and apoptosis in hormone independent prostate cancer DU-145 cells by down regulating Notch signaling

(2016) Jian Sha et al.   BIOMEDICINE & PHARMACOTHERAPY

Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases

(2016) Ajaikumar B Kunnumakkara et al.   BRITISH JOURNAL OF PHARMACOLOGY

Revealing the effect of 6-gingerol, 6-shogaol and curcumin on mPGES-1, GSK-3β and β-catenin pathway in A549 cell line

(2016) Demirpolat Eren et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Curcumin inhibits metastasis in human papillary thyroid carcinoma BCPAP cells via down-regulation of the TGF-β/Smad2/3 signaling pathway

(2016) Li Zhang et al.   EXPERIMENTAL CELL RESEARCH

Curcumin inhibits tumor epithelial-mesenchymal transition by downregulating the Wnt signaling pathway and upregulating NKD2 expression in colon cancer cells

(2016) ZEWEI ZHANG et al.   ONCOLOGY REPORTS

Curcumin inhibits hypoxia-induced epithelial-mesenchymal transition in pancreatic cancer cells via suppression of the hedgehog signaling pathway

(2016) LEI CAO et al.   ONCOLOGY REPORTS

Pyridine analogues of curcumin exhibit high activity for inhibiting CWR-22Rv1 human prostate cancer cell growth and androgen receptor activation

(2016) DAI-YING ZHOU et al.   Oncology Letters

Role of Wnt Inhibitory Factor-1 in Inhibition of Bisdemethoxycurcumin Mediated Epithelial-to-Mesenchymal Transition in Highly Metastatic Lung Cancer 95D Cells

(2015) He-Ping Yang et al.   CHINESE MEDICAL JOURNAL

MEK inhibition prevents tumour-shed transforming growth factor-β-induced T-regulatory cell augmentation in tumour milieu

(2015) Dewan M. S. Hossain et al.   IMMUNOLOGY

Curcumin inhibits cancer-associated fibroblast-driven prostate cancer invasion through MAOA/mTOR/HIF-1α signaling

(2015) YUEFENG DU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Curcumin-mediated regulation of Notch1/hairy and enhancer of split-1/survivin: molecular targeting in cholangiocarcinoma

(2015) Steven Koprowski et al.   JOURNAL OF SURGICAL RESEARCH

Curcumin induces autophagy, inhibits proliferation and invasion by downregulating AKT/mTOR signaling pathway in human melanoma cells

(2015) GUANGMING ZHAO et al.   ONCOLOGY REPORTS

miR-146b-5p mediates p16-dependent repression of IL-6 and suppresses paracrine procarcinogenic effects of breast stromal fibroblasts

(2015) Mysoon M. Al-Ansari et al.   Oncotarget

Synthesis of diethylamino-curcumin mimics with substituted triazolyl groups and their sensitization effect of TRAIL against brain cancer cells

(2014) Yongchel Ahn et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Chemistry of Curcumin: From Extraction to Therapeutic Agent

(2014) Kavirayani Priyadarsini   MOLECULES

Therapeutic modulation of Notch signalling — are we there yet?

(2014) Emma R. Andersson et al.   NATURE REVIEWS DRUG DISCOVERY

Curcumin suppresses cell proliferation through inhibition of the Wnt/β-catenin signaling pathway in medulloblastoma

(2014) MISI HE et al.   ONCOLOGY REPORTS

Recent Developments in Delivery, Bioavailability, Absorption and Metabolism of Curcumin: the Golden Pigment from Golden Spice

(2014) Sahdeo Prasad et al.   Cancer Research and Treatment

Curcumin Inhibits TGF-β1-Induced MMP-9 and Invasion through ERK and Smad Signaling in Breast Cancer MDA-MB-231 Cells

(2013) Na Mo et al.   Asian Pacific Journal of Cancer Prevention

Curcumin Suppresses Malignant Glioma Cells Growth and Induces Apoptosis by Inhibition of SHH/GLI1 Signaling Pathwayin VitroandVivo

(2013) Wen-Zhong Du et al.   CNS Neuroscience & Therapeutics

Curcumin induces apoptosis in human colorectal carcinoma (HCT-15) cells by regulating expression of Prp4 and p53

(2013) Adeeb Shehzad et al.   MOLECULES AND CELLS

Role of TGF-β signaling in curcumin-mediated inhibition of tumorigenicity of human lung cancer cells

(2012) Raktima Datta et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Curcuminoids Block TGF-β Signaling in Human Breast Cancer Cells and Limit Osteolysis in a Murine Model of Breast Cancer Bone Metastasis

(2012) Laura E. Wright et al.   JOURNAL OF NATURAL PRODUCTS

Curcumin Induces Cell Death in Esophageal Cancer Cells through Modulating Notch Signaling

(2012) Dharmalingam Subramaniam et al.   PLoS One

Structurally Modified Curcumin Analogs Inhibit STAT3 Phosphorylation and Promote Apoptosis of Human Renal Cell Carcinoma and Melanoma Cell Lines

(2012) Matthew A. Bill et al.   PLoS One