Jolkinolide B inhibits glycolysis by downregulating hexokinase 2 expression through inactivating the Akt/mTOR pathway in non-small cell lung cancer cells

ent-Abietane Lactones from Euphorbia

(2017) Jia-Zhuo Lai et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Albendazole inhibits HIF-1α-dependent glycolysis and VEGF expression in non-small cell lung cancer cells

(2017) Fang Zhou et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Glycometabolic adaptation mediates the insensitivity of drug-resistant K562/ADM leukaemia cells to adriamycin via the AKT-mTOR/c-Myc signalling pathway

(2017) Xueyan Zhang et al.   Molecular Medicine Reports

MicroRNA-124 suppresses proliferation and glycolysis in non–small cell lung cancer cells by targeting AKT–GLUT1/HKII

(2017) Xiaojian Zhao et al.   TUMOR BIOLOGY

Jolkinolide A and Jolkinolide B Inhibit Proliferation of A549 Cells and Activity of Human Umbilical Vein Endothelial Cells

(2017) Lei Shen et al.   MEDICAL SCIENCE MONITOR

Inhibition of glycolytic enzyme hexokinase II (HK2) suppresses lung tumor growth

(2016) Huanan Wang et al.   Cancer Cell International

Jolkinolide B induces apoptosis and inhibits tumor growth in mouse melanoma B16F10 cells by altering glycolysis

(2016) Caixia Gao et al.   Scientific Reports

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Anti-metastatic effect of jolkinolide B and the mechanism of activity in breast cancer MDA-MB-231 cells

(2015) CHAO SUN et al.   Oncology Letters

Review of aerobic glycolysis and its key enzymes - new targets for lung cancer therapy

(2015) Xue-bing Li et al.   Thoracic Cancer

RETRACTED ARTICLE: Text mining and network analysis of molecular interaction in non-small cell lung cancer by using natural language processing

(2014) Jun Li et al.   MOLECULAR BIOLOGY REPORTS

Cancer-generated lactic acid: a regulatory, immunosuppressive metabolite?

(2013) Stephen Yiu Chuen Choi et al.   JOURNAL OF PATHOLOGY

Jolkinolide B from Euphorbia fischeriana Steud induces in human leukemic cells apoptosis via JAK2/STAT3 pathways

(2012) Jia-He Wang et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

MicroRNA-143 (miR-143) Regulates Cancer Glycolysis via Targeting Hexokinase 2 Gene

(2012) Rong Fang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-143 regulates hexokinase 2 expression in cancer cells

(2012) A Peschiaroli et al.   ONCOGENE

Jolkinolide B induces apoptosis in MCF-7 cells through inhibition of the PI3K/Akt/mTOR signaling pathway

(2012) HUI-YU XU et al.   ONCOLOGY REPORTS

The acidity of the tumor microenvironment is a mechanism of immune escape that can be overcome by proton pump inhibitors

(2012) Matteo Bellone et al.   OncoImmunology

Jolkinolide B from Euphorbia fischeriana Steud induces apoptosis in human leukemic U937 cells through PI3K/Akt and XIAP pathways

(2011) Jia-He Wang et al.   MOLECULES AND CELLS

The Warburg and Crabtree effects: On the origin of cancer cell energy metabolism and of yeast glucose repression

(2010) Rodrigo Diaz-Ruiz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Analyses of Resected Human Brain Metastases of Breast Cancer Reveal the Association between Up-Regulation of Hexokinase 2 and Poor Prognosis

(2009) D. Palmieri et al.   MOLECULAR CANCER RESEARCH