Crocin improves renal function by declining Nox-4, IL-18, and p53 expression levels in an experimental model of diabetic nephropathy

Oxidative stress induces renal failure: A review of possible molecular pathways

(2018) Habib Yaribeygi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Gastroprotective effect of crocin in ethanol-induced gastric injury in rats

(2015) Shohda A. El-Maraghy et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Crocin exerts anti-inflammatory and anti-catabolic effects on rat intervertebral discs by suppressing the activation of JNK

(2015) KANG LI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Defective Autophagosome Formation in p53-Null Colorectal Cancer Reinforces Crocin-Induced Apoptosis

(2015) Amr Amin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protective effects of saffron (its active constituent, crocin) on nephropathy in streptozotocin-induced diabetic rats

(2014) E Altinoz et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Transforming Growth Factor-β–Induced Cross Talk Between p53 and a MicroRNA in the Pathogenesis of Diabetic Nephropathy

(2013) Supriya D. Deshpande et al.   DIABETES

Hemin Therapy Improves Kidney Function in Male Streptozotocin-Induced Diabetic Rats: Role of the Heme Oxygenase/Atrial Natriuretic Peptide/Adiponectin Axis

(2013) Joseph Fomusi Ndisang et al.   ENDOCRINOLOGY

Crocin attenuates cisplatin-induced liver injury in the mice

(2013) Y Sun et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

The worldwide diabetes epidemic

(2013) David W. Lam et al.   Current Opinion in Endocrinology Diabetes and Obesity

A dietary colorant crocin mitigates arthritis and associated secondary complications by modulating cartilage deteriorating enzymes, inflammatory mediators and antioxidant status

(2012) M. Hemshekhar et al.   BIOCHIMIE

Inflammation and the pathogenesis of diabetic nephropathy

(2012) Jun Wada et al.   CLINICAL SCIENCE

Type 2 Diabetes: An Epidemic Requiring Global Attention and Urgent Action

(2012) W. H. Herman et al.   DIABETES CARE

Crocin “saffron” protects against beryllium chloride toxicity in rats through diminution of oxidative stress and enhancing gene expression of antioxidant enzymes

(2012) Hesham A. El-Beshbishy et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy

(2011) Yashpal S. Kanwar et al.   Annual Review of Pathology-Mechanisms of Disease

Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice

(2011) Takahiro Kodama et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy

(2011) Juan F. Navarro-González et al.   Nature Reviews Nephrology

Interleukin-18 contributes more closely to the progression of diabetic nephropathy than other diabetic complications

(2010) Takayuki Fujita et al.   ACTA DIABETOLOGICA

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Oxidative Stress in Diabetic Nephropathy

(2010) N. Kashihara et al.   CURRENT MEDICINAL CHEMISTRY

Anti-inflammatory effects of crocin and crocetin in rat brain microglial cells

(2010) Kyong Nyon Nam et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Crocus sativus L. (saffron) attenuates isoproterenol-induced myocardial injury via preserving cardiac functions and strengthening antioxidant defense system

(2010) Jaspreet Sachdeva et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

AMP-activated Protein Kinase (AMPK) Negatively Regulates Nox4-dependent Activation of p53 and Epithelial Cell Apoptosis in Diabetes

(2010) Assaad A. Eid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Advanced Glycation end Products, Oxidative Stress and Diabetic Nephropathy

(2010) Sho-ichi Yamagishi et al.   Oxidative Medicine and Cellular Longevity

Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways

(2009) A. J. Schetter et al.   CARCINOGENESIS

Upregulated IL-18 expression in type 2 diabetic subjects with nephropathy: TGF-β1 enhanced IL-18 expression in human renal proximal tubular epithelial cells

(2008) Kazunari Miyauchi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Change in histone H3 phosphorylation, MAP kinase p38, SIR 2 and p53 expression by resveratrol in preventing streptozotocin induced type I diabetic nephropathy

(2008) Kulbhushan Tikoo et al.   FREE RADICAL RESEARCH