Actin cytoskeleton assembly regulates collagen production via TGF-β type II receptor in human skin fibroblasts

Reduction of fibroblast size/mechanical force down-regulates TGF-β type II receptor: implications for human skin aging

(2015) Gary J. Fisher et al.   AGING CELL

Role of Age-Associated Alterations of the Dermal Extracellular Matrix Microenvironment in Human Skin Aging: A Mini-Review

(2015) Taihao Quan et al.   GERONTOLOGY

Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the US Population, 2012

(2015) Howard W. Rogers et al.   JAMA Dermatology

Oxidative exposure impairs TGF-β pathway via reduction of type II receptor and SMAD3 in human skin fibroblasts

(2014) Tianyuan He et al.   AGE

Age-associated reduction of cellular spreading/mechanical force up-regulates matrix metalloproteinase-1 expression and collagen fibril fragmentation via c-Jun/AP-1 in human dermal fibroblasts

(2014) Zhaoping Qin et al.   AGING CELL

Sensing the local environment: actin architecture and Hippo signalling

(2014) Pedro Gaspar et al.   CURRENT OPINION IN CELL BIOLOGY

The extracellular matrix modulates the hallmarks of cancer

(2014) M. W. Pickup et al.   EMBO REPORTS

Mechanobiology and Developmental Control

(2013) Tadanori Mammoto et al.   Annual Review of Cell and Developmental Biology

Elevated Matrix Metalloproteinases and Collagen Fragmentation in Photodamaged Human Skin: Impact of Altered Extracellular Matrix Microenvironment on Dermal Fibroblast Function

(2013) Taihao Quan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Enhancing Structural Support of the Dermal Microenvironment Activates Fibroblasts, Endothelial Cells, and Keratinocytes in Aged Human Skin In Vivo

(2012) Taihao Quan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

MicroRNA-21 induces stemness by downregulating transforming growth factor beta receptor 2 (TGF R2) in colon cancer cells

(2011) Y. Yu et al.   CARCINOGENESIS

Molecular aspects of skin ageing

(2011) Elizabeth C. Naylor et al.   MATURITAS

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Linking actin dynamics and gene transcription to drive cellular motile functions

(2010) Eric N. Olson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TGF-β and fibrosis in different organs — molecular pathway imprints

(2009) Dirk Pohlers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Reduced Expression of Connective Tissue Growth Factor (CTGF/CCN2) Mediates Collagen Loss in Chronologically Aged Human Skin

(2009) TaiHao Quan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Collagen Fragmentation Promotes Oxidative Stress and Elevates Matrix Metalloproteinase-1 in Fibroblasts in Aged Human Skin

(2008) Gary J. Fisher et al.   AMERICAN JOURNAL OF PATHOLOGY

Looking Older

(2008) Gary J. Fisher et al.   ARCHIVES OF DERMATOLOGY

miR-21 Gene Expression Triggered by AP-1 Is Sustained through a Double-Negative Feedback Mechanism

(2008) Shuji Fujita et al.   JOURNAL OF MOLECULAR BIOLOGY

Environmental sensing through focal adhesions

(2008) Benjamin Geiger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY