Increased free Zn2+ correlates induction of sarco(endo)plasmic reticulum stress via altered expression levels of Zn2+ -transporters in heart failure

Reduction in Na+ current by angiotensin II is mediated by PKCα in mouse and human-induced pluripotent stem cell–derived cardiomyocytes

(2016) Sophie Mathieu et al.   HEART RHYTHM

Molecular Genetic Regulation ofSlc30a8/ZnT8 Reveals a Positive Association With Glucose Tolerance

(2016) Ryan K. Mitchell et al.   MOLECULAR ENDOCRINOLOGY

Over-expression of Slc30a8/ZnT8 selectively in the mouse α cell impairs glucagon release and responses to hypoglycemia

(2016) Antonia Solomou et al.   Nutrition & Metabolism

Signaling Pathways in Cardiac Myocyte Apoptosis

(2016) Peng Xia et al.   Biomed Research International

Protein kinase Cα inhibits myocardin-induced cardiomyocyte hypertrophy through the promotion of myocardin phosphorylation

(2015) Weizong Li et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Mechanotransduction in Cardiac Hypertrophy and Failure

(2015) R. C. Lyon et al.   CIRCULATION RESEARCH

Intracellular Zinc Modulates Cardiac Ryanodine Receptor-mediated Calcium Release

(2015) Jason Woodier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Relationship between the architecture of zinc coordination and zinc binding affinity in proteins – insights into zinc regulation

(2015) Tomasz Kochańczyk et al.   Metallomics

Beta-blocker timolol alleviates hyperglycemia-induced cardiac damage via inhibition of endoplasmic reticulum stress

(2014) Figen Amber Cicek et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

(2014) Jason Flannick et al.   NATURE GENETICS

Enhancement of Cellular Antioxidant-Defence Preserves Diastolic Dysfunction via Regulation of Both Diastolic Zn2+and Ca2+and Prevention of RyR2-Leak in Hyperglycemic Cardiomyocytes

(2014) Erkan Tuncay et al.   Oxidative Medicine and Cellular Longevity

Zinc transporter 8 (ZnT8) and β cell function

(2014) Howard W. Davidson et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder

(2014) Alexandra Grubman et al.   Acta Neuropathologica Communications

ZIP14 and DMT1 in the liver, pancreas, and heart are differentially regulated by iron deficiency and overload: implications for tissue iron uptake in iron-related disorders

(2013) H. Nam et al.   HAEMATOLOGICA

Essential Role of the Zinc Transporter ZIP9/SLC39A9 in Regulating the Activations of Akt and Erk in B-Cell Receptor Signaling Pathway in DT40 Cells

(2013) Masanari Taniguchi et al.   PLoS One

ß-Blocker Timolol Prevents Arrhythmogenic Ca2+ Release and Normalizes Ca2+ and Zn2+ Dyshomeostasis in Hyperglycemic Rat Heart

(2013) Erkan Tuncay et al.   PLoS One

PKCα-Specific Phosphorylation of the Troponin Complex in Human Myocardium: A Functional and Proteomics Analysis

(2013) Viola Kooij et al.   PLoS One

Protein kinase CK2 opens the gate for zinc signaling

(2012) Kathryn M. Taylor et al.   CELL CYCLE

Zinc and the modulation of redox homeostasis

(2012) Patricia I. Oteiza   FREE RADICAL BIOLOGY AND MEDICINE

Roles of ZIP8, ZIP14, and DMT1 in transport of cadmium and manganese in mouse kidney proximal tubule cells

(2012) Hitomi Fujishiro et al.   Metallomics

ZIP8 Zinc Transporter: Indispensable Role for Both Multiple-Organ Organogenesis and Hematopoiesis In Utero

(2012) Marina Gálvez-Peralta et al.   PLoS One

Modulation of AT-1R/AMPK-MAPK cascade plays crucial role for the pathogenesis of diabetic cardiomyopathy in transgenic type 2 diabetic (Spontaneous Diabetic Torii) rats

(2011) Arun Prasath Lakshmanan et al.   BIOCHEMICAL PHARMACOLOGY

Endoplasmic Reticulum Stress and Diabetic Cardiomyopathy

(2011) Jiancheng Xu et al.   Experimental Diabetes Research

Nucleo-cytosolic Shuttling of FoxO1 Directly Regulates MouseIns2but NotIns1Gene Expression in Pancreatic Beta Cells (MIN6)

(2011) Gargi Meur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucose Regulates Free Cytosolic Zn2+Concentration, Slc39 (ZiP), and Metallothionein Gene Expression in Primary Pancreatic Islet β-Cells

(2011) Elisa A. Bellomo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zinc homeostasis and signaling in health and diseases

(2011) Toshiyuki Fukada et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Biochemical markers in heart failure

(2011) Yukihito Sato et al.   Journal of Cardiology

Intracellular free zinc during cardiac excitation–contraction cycle: calcium and redox dependencies

(2010) Erkan Tuncay et al.   CARDIOVASCULAR RESEARCH

WNT1-inducible signaling pathway protein-1 activates diverse cell survival pathways and blocks doxorubicin-induced cardiomyocyte death

(2010) Balachandar Venkatesan et al.   CELLULAR SIGNALLING

ZRT/IRT-like Protein 14 (ZIP14) Promotes the Cellular Assimilation of Iron from Transferrin

(2010) Ningning Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Kinase Cα, but Not PKCβ or PKCγ, Regulates Contractility and Heart Failure Susceptibility

(2009) Qinghang Liu et al.   CIRCULATION RESEARCH

Correlation Between Atrial ZnT-1 Expression and Atrial Fibrillation in Humans: A Pilot Study

(2007) YORAM ETZION et al.   JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY