Multiple roles of Ring 1 and YY1 binding protein in physiology and disease

TMPRSS2–ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer

(2017) Ken J Kron et al.   NATURE GENETICS

RYBP Inhibits Progression and Metastasis of Lung Cancer by Suppressing EGFR Signaling and Epithelial-Mesenchymal Transition

(2017) Xiaoxiao Dinglin et al.   Translational Oncology

Forced Activation of Notch in Macrophages Represses Tumor Growth by Upregulating miR-125a and Disabling Tumor-Associated Macrophages

(2016) Jun-Long Zhao et al.   CANCER RESEARCH

Proapoptotic RYBP interacts with FANK1 and induces tumor cell apoptosis through the AP-1 signaling pathway

(2016) Wen Ma et al.   CELLULAR SIGNALLING

RING1 and YY1 binding protein suppresses breast cancer growth and metastasis

(2016) Hongyan Zhou et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

RYBP Expression Is Regulated by KLF4 and Sp1 and Is Related to Hepatocellular Carcinoma Prognosis

(2016) Qiaojiajie Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression and clinical significance of PcG-associated protein RYBP in hepatocellular carcinoma

(2016) Xiaonian Zhu et al.   Oncology Letters

RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes

(2016) Nathan R Rose et al.   eLife

Absence of Rybp Compromises Neural Differentiation of Embryonic Stem Cells

(2016) Gergo Kovacs et al.   Stem Cells International

RYBP predicts survival of patients with non-small cell lung cancer and regulates tumor cell growth and the response to chemotherapy

(2015) Sukesh Voruganti et al.   CANCER LETTERS

YY1 regulates melanoma tumorigenesis through a miR-9 ~ RYBP axis

(2015) Guowei Zhao et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Targeting Polycomb systems to regulate gene expression: modifications to a complex story

(2015) Neil P. Blackledge et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lack of Rybp in Mouse Embryonic Stem Cells Impairs Cardiac Differentiation

(2015) Olga Ujhelly et al.   STEM CELLS AND DEVELOPMENT

A novel dRYBP–SCF complex functions to inhibit apoptosis in Drosophila

(2013) Sol Fereres et al.   APOPTOSIS

Identification of eight candidate target genes of the recurrent 3p12-p14 loss in cervical cancer by integrative genomic profiling

(2013) Malin Lando et al.   JOURNAL OF PATHOLOGY

Recurrent deletion of 3p13 targets multiple tumour suppressor genes and defines a distinct subgroup of aggressiveERGfusion-positive prostate cancers

(2013) Antje Krohn et al.   JOURNAL OF PATHOLOGY

A new world of Polycombs: unexpected partnerships and emerging functions

(2013) Yuri B. Schwartz et al.   NATURE REVIEWS GENETICS

Altered Expression of Polycomb Group Genes in Glioblastoma Multiforme

(2013) Gang Li et al.   PLoS One

Integrative analysis of prostate cancer aggressiveness

(2013) Elisabeth Feik et al.   PROSTATE

RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3

(2012) Lígia Tavares et al.   CELL

Nonoverlapping Functions of the Polycomb Group Cbx Family of Proteins in Embryonic Stem Cells

(2012) Lluis Morey et al.   Cell Stem Cell

A Novel Target of MicroRNA-29, Ring1 and YY1-binding Protein (Rybp), Negatively Regulates Skeletal Myogenesis

(2012) Liang Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RYBP Represses Endogenous Retroviruses and Preimplantation- and Germ Line-Specific Genes in Mouse Embryonic Stem Cells

(2012) K. Hisada et al.   MOLECULAR AND CELLULAR BIOLOGY

PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes

(2012) Zhonghua Gao et al.   MOLECULAR CELL

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

RYBP and Cbx7 Define Specific Biological Functions of Polycomb Complexes in Mouse Embryonic Stem Cells

(2012) Lluis Morey et al.   Cell Reports

Overexpression of enhancer of zeste homolog 2 with trimethylation of lysine 27 on histone H3 in adult T-cell leukemia/lymphoma as a target for epigenetic therapy

(2011) D. Sasaki et al.   HAEMATOLOGICA

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer

(2010) Martin Sauvageau et al.   Cell Stem Cell

Targeting the p53 Pathway of Apoptosis

(2010) Joana D. Amaral et al.   CURRENT PHARMACEUTICAL DESIGN

Polycomb Group Targeting through Different Binding Partners of RING1B C-Terminal Domain

(2010) Renjing Wang et al.   STRUCTURE

The Transcriptional Repressor RYBP Is a Natively Unfolded Protein Which Folds upon Binding to DNA†

(2009) José L. Neira et al.   BIOCHEMISTRY

High levels of dRYBP induce apoptosis in Drosophila imaginal cells through the activation of reaper and the requirement of trithorax, dredd and dFADD

(2009) Inma González et al.   CELL RESEARCH

Mechanisms of Polycomb gene silencing: knowns and unknowns

(2009) Jeffrey A. Simon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Gene Dosage, Expression, and Ontology Analysis Identifies Driver Genes in the Carcinogenesis and Chemoradioresistance of Cervical Cancer

(2009) Malin Lando et al.   PLoS Genetics

Adenoviral-mediated Rybp expression promotes tumor cell-specific apoptosis

(2008) R L Novak et al.   CANCER GENE THERAPY

RYBP stabilizes p53 by modulating MDM2

(2008) Deng Chen et al.   EMBO REPORTS

Functional Characterization of the dRYBP Gene in Drosophila

(2008) I. Gonzalez et al.   GENETICS