MICAL1 facilitates breast cancer cell proliferation via ROS-sensitive ERK/cyclin D pathway

MICAL1 controls cell invasive phenotype via regulating oxidative stress in breast cancer cells

(2016) Wenjie Deng et al.   BMC CANCER

Heat shock protein 27 downstream of P38-PI3K/Akt signaling antagonizes melatonin-induced apoptosis of SGC-7901 gastric cancer cells

(2016) Wenjie Deng et al.   Cancer Cell International

F-actin dismantling through a redox-driven synergy between Mical and cofilin

(2016) Elena E. Grintsevich et al.   NATURE CELL BIOLOGY

TRIM44 promotes proliferation and metastasis in non‑small cell lung cancer via mTOR signaling pathway

(2016) Ying Xing et al.   Oncotarget

Myc and cell cycle control

(2015) Gabriel Bretones et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Silencing of MICAL-L2 suppresses malignancy of ovarian cancer by inducing mesenchymal–epithelial transition

(2015) Lin-Yan Zhu et al.   CANCER LETTERS

DDX5 promotes proliferation and tumorigenesis of non-small-cell lung cancer cells by activating β-catenin signaling pathway

(2015) Zhendong Wang et al.   CANCER SCIENCE

MICAL2 is a novel human cancer gene controlling mesenchymal to epithelial transition involved in cancer growth and invasion

(2015) Sara Mariotti et al.   Oncotarget

Semaphorin3A elevates vascular permeability and contributes to cerebral ischemia-induced brain damage

(2015) Sheng Tao Hou et al.   Scientific Reports

Sema6A and Mical1 control cell growth and survival of BRAFV600E human melanoma cells

(2015) Rossella Loria et al.   Oncotarget

The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections

(2014) Eljo Y. Van Battum et al.   Nature Communications

MICAL-Family Proteins: Complex Regulators of the Actin Cytoskeleton

(2013) Sai Srinivas Panapakkam Giridharan et al.   ANTIOXIDANTS & REDOX SIGNALING

SelR reverses Mical-mediated oxidation of actin to regulate F-actin dynamics

(2013) Ruei-Jiun Hung et al.   NATURE CELL BIOLOGY

Differential regulation of actin microfilaments by human MICAL proteins

(2012) S. S. P. Giridharan et al.   JOURNAL OF CELL SCIENCE

How cancer metabolism is tuned for proliferation and vulnerable to disruption

(2012) Almut Schulze et al.   NATURE

Protein-bound polysaccharide from Phellinus linteus inhibits tumor growth, invasion, and angiogenesis and alters Wnt/β-catenin in SW480 human colon cancer cells

(2011) Kyoung-Sub Song et al.   BMC CANCER

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

ROS-activated p38 MAPK/ERK-Akt cascade plays a central role in palmitic acid-stimulated hepatocyte proliferation

(2011) Xin Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling

(2011) P. P. Provenzano et al.   JOURNAL OF CELL SCIENCE

MICAL-1 Is a Negative Regulator of MST-NDR Kinase Signaling and Apoptosis

(2011) Y. Zhou et al.   MOLECULAR AND CELLULAR BIOLOGY

Direct Redox Regulation of F-Actin Assembly and Disassembly by Mical

(2011) R.-J. Hung et al.   SCIENCE

Thioredoxin Mediates Oxidation-Dependent Phosphorylation of CRMP2 and Growth Cone Collapse

(2011) A. Morinaka et al.   Science Signaling

Mical links semaphorins to F-actin disassembly

(2010) Ruei-Jiun Hung et al.   NATURE

Lysophosphatidic Acid Induces MDA-MB-231 Breast Cancer Cells Migration through Activation of PI3K/PAK1/ERK Signaling

(2010) Jun Du et al.   PLoS One

Daintain/AIF-1 promotes breast cancer proliferation via activation of the NF-κB/cyclin D1 pathway and facilitates tumor growth

(2008) Shou Liu et al.   CANCER SCIENCE