Does p53 Inhibition Suppress Myocardial Ischemia–Reperfusion Injury?

Chronic Treatment With an Erythropoietin Receptor Ligand Prevents Chronic Kidney Disease–Induced Enlargement of Myocardial Infarct SizeNovelty and Significance

(2016) Keitaro Nishizawa et al.   HYPERTENSION

p53-Induced inflammation exacerbates cardiac dysfunction during pressure overload

(2015) Yohko Yoshida et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Pivotal Role of mTORC2 and Involvement of Ribosomal Protein S6 in Cardioprotective Signaling

(2014) Toshiyuki Yano et al.   CIRCULATION RESEARCH

Translocation of Glycogen Synthase Kinase-3β (GSK-3β), a Trigger of Permeability Transition, Is Kinase Activity-dependent and Mediated by Interaction with Voltage-dependent Anion Channel 2 (VDAC2)

(2014) Masaya Tanno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis

(2012) Angelina V. Vaseva et al.   CELL

p53-Induced Adipose Tissue Inflammation Is Critically Involved in the Development of Insulin Resistance in Heart Failure

(2012) Ippei Shimizu et al.   Cell Metabolism

The mPTP and its regulatory proteins: final common targets of signalling pathways for protection against necrosis

(2011) T. Miura et al.   CARDIOVASCULAR RESEARCH

p53 Promotes Cardiac Dysfunction in Diabetic Mellitus Caused by Excessive Mitochondrial Respiration-Mediated Reactive Oxygen Species Generation and Lipid Accumulation

(2011) Hideo Nakamura et al.   Circulation-Heart Failure

p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia

(2011) Atsushi Hoshino et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

What makes the mitochondria a killer? Can we condition them to be less destructive?

(2010) Elizabeth Murphy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Hypertensive Hypertrophied Myocardium Is Vulnerable to Infarction and Refractory to Erythropoietin-Induced Protection

(2010) Toshiyuki Yano et al.   HYPERTENSION

Mitochondrial localization of the low level p53 protein in proliferative cells

(2009) Ioana Ferecatu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Short Communication: Angiotensin II Type 1 Receptor–Mediated Upregulation of Calcineurin Activity Underlies Impairment of Cardioprotective Signaling in Diabetic Hearts

(2009) Hiroyuki Hotta et al.   CIRCULATION RESEARCH

Endoplasmic Reticulum Stress in Diabetic Hearts Abolishes Erythropoietin-Induced Myocardial Protection by Impairment of Phospho–Glycogen Synthase Kinase-3β–Mediated Suppression of Mitochondrial Permeability Transition

(2009) Takayuki Miki et al.   DIABETES

Inhibition of Glycogen Synthase Kinase or the Apoptotic Protein p53 Lowers the Threshold of Helium Cardioprotection In Vivo: The Role of Mitochondrial Permeability Transition

(2008) Paul S. Pagel et al.   ANESTHESIA AND ANALGESIA

Glycogen Synthase Kinase 3 Inhibition Slows Mitochondrial Adenine Nucleotide Transport and Regulates Voltage-Dependent Anion Channel Phosphorylation

(2008) Samarjit Das et al.   CIRCULATION RESEARCH

INHIBITION OF p53 BY PIFITHRIN-α REDUCES MYOCYTE APOPTOSIS AND LEUKOCYTE TRANSMIGRATION IN AGED RAT HEARTS FOLLOWING 24 HOURS OF REPERFUSION

(2008) Peitan Liu et al.   SHOCK