Inhibition of CaMKK2 Enhances Fracture Healing by Stimulating Indian Hedgehog Signaling and Accelerating Endochondral Ossification

Fracture healing: A review of clinical, imaging and laboratory diagnostic options

(2017) Brian P. Cunningham et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Pharmacological rescue of diabetic skeletal stem cell niches

(2017) Ruth Tevlin et al.   Science Translational Medicine

Pharmacological inhibition of CaMKK2 with the selective antagonist STO-609 regresses NAFLD

(2017) Brian York et al.   Scientific Reports

Micro-computed tomography assisted distal femur metaphyseal blunt punch compression for determining trabecular bone strength in mice

(2016) Uma Sankar et al.   JOURNAL OF BIOMECHANICS

Osteogenic Differentiation of Periosteal Cells During Fracture Healing

(2016) Tao Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Fracture healing physiology and the quest for therapies for delayed healing and nonunion

(2016) Paul Kostenuik et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Research Resource: Roles for Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) in Systems Metabolism

(2016) Kathrina L. Marcelo et al.   MOLECULAR ENDOCRINOLOGY

Inhibition of CaMKK2 reverses age-associated decline in bone mass

(2015) Zachary J. Pritchard et al.   BONE

Bmp2 conditional knockout in osteoblasts and endothelial cells does not impair bone formation after injury or mechanical loading in adult mice

(2015) Sarah Howe McBride-Gagyi et al.   BONE

A novel crosstalk between calcium/calmodulin kinases II and IV regulates cell proliferation in myeloid leukemia cells

(2015) Sara Monaco et al.   CELLULAR SIGNALLING

Vasculature-Associated Cells Expressing Nestin in Developing Bones Encompass Early Cells in the Osteoblast and Endothelial Lineage

(2014) Noriaki Ono et al.   DEVELOPMENTAL CELL

Delayed union and nonunions: Epidemiology, clinical issues, and financial aspects

(2014) David J. Hak et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Fracture healing: mechanisms and interventions

(2014) Thomas A. Einhorn et al.   Nature Reviews Rheumatology

Periosteal cells are a major source of soft callus in bone fracture

(2013) Hiroki Murao et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Inhibition of Ca2+/Calmodulin-Dependent Protein Kinase Kinase 2 Stimulates Osteoblast Formation and Inhibits Osteoclast Differentiation

(2013) Rachel L Cary et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Type 2 diabetes and bone fractures

(2013) Kendall F. Moseley   Current Opinion in Endocrinology Diabetes and Obesity

Calcium/Calmodulin-dependent Protein Kinase Kinase 2 Regulates Macrophage-mediated Inflammatory Responses

(2012) Luigi Racioppi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium/Calmodulin-dependent Protein Kinase Kinase 2: Roles in Signaling and Pathophysiology

(2012) Luigi Racioppi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of CaMKK2 from the Liver Lowers Blood Glucose and Improves Whole-Body Glucose Tolerance in the Mouse

(2012) Kristin A. Anderson et al.   MOLECULAR ENDOCRINOLOGY

Differential Expression of Surface Markers in Mouse Bone Marrow Mesenchymal Stromal Cell Subpopulations with Distinct Lineage Commitment

(2012) Maria Rostovskaya et al.   PLoS One

Characterization of the CaMKKβ–AMPK signaling complex

(2011) Michelle F. Green et al.   CELLULAR SIGNALLING

Crystal Structure of the Ca2+/Calmodulin-dependent Protein Kinase Kinase in Complex with the Inhibitor STO-609

(2011) Mutsuko Kukimoto-Niino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium/calmodulin-dependent protein kinase II activity regulates the proliferative potential of growth plate chondrocytes

(2010) Y. Li et al.   DEVELOPMENT

Osteoblast Precursors, but Not Mature Osteoblasts, Move into Developing and Fractured Bones along with Invading Blood Vessels

(2010) Christa Maes et al.   DEVELOPMENTAL CELL

Emerging Bone Healing Therapies

(2010) Richard Marsell et al.   JOURNAL OF ORTHOPAEDIC TRAUMA

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

Timing of Subsequent Fractures after an Initial Fracture

(2010) Tineke A. C. M. van Geel et al.   Current Osteoporosis Reports

Mice expressing GFP and CreER in osteochondro progenitor cells in the periosteum

(2009) Aya Kawanami et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular Mechanisms Controlling Bone Formation during Fracture Healing and Distraction Osteogenesis

(2009) Z.S. AI-Aql et al.   JOURNAL OF DENTAL RESEARCH

BDNF-Mediated Cerebellar Granule Cell Development Is Impaired in Mice Null for CaMKK2 or CaMKIV

(2009) M. Kokubo et al.   JOURNAL OF NEUROSCIENCE

Recombinant human parathyroid hormone (PTH 1-34) and low-intensity pulsed ultrasound have contrasting additive effects during fracture healing

(2008) Stuart J. Warden et al.   BONE

Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells

(2008) J. Pratap et al.   CANCER RESEARCH

Hypothalamic CaMKK2 Contributes to the Regulation of Energy Balance

(2008) Kristin A. Anderson et al.   Cell Metabolism

Ca2+/Calmodulin-dependent kinase II signaling causes skeletal overgrowth and premature chondrocyte maturation

(2008) Michael J. Taschner et al.   DEVELOPMENTAL BIOLOGY

Commentary: The Year in Basic Science: Calmodulin Kinase Cascades

(2008) Anthony R. Means   MOLECULAR ENDOCRINOLOGY

Bone remodeling during fracture repair: The cellular picture

(2008) Aaron Schindeler et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY