Lipid-mediated signals that regulate mitochondrial biology

Cardiolipin Regulates Mitophagy through the Protein Kinase C Pathway

(2017) Zheni Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sterol Oxidation Mediates Stress-Responsive Vms1 Translocation to Mitochondria

(2017) Jason R. Nielson et al.   MOLECULAR CELL

Rapid, direct activity assays for Smoothened reveal Hedgehog pathway regulation by membrane cholesterol and extracellular sodium

(2017) Benjamin R. Myers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy

(2016) V E Kagan et al.   CELL DEATH AND DIFFERENTIATION

Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism

(2016) Bhagirath Chaurasia et al.   Cell Metabolism

Diverting CERT-mediated ceramide transport to mitochondria triggers Bax-dependent apoptosis

(2016) Amrita Jain et al.   JOURNAL OF CELL SCIENCE

Sphingosine kinase 2 and sphingosine-1-phosphate promotes mitochondrial function in dopaminergic neurons of mouse model of Parkinson’s disease and in MPP+-treated MN9D cells in vitro

(2015) M. Sivasubramanian et al.   NEUROSCIENCE

Sphingosine kinase 1 dependent protein kinase C-δ activation plays an important role in acute liver failure in mice

(2015) Yan-Chang Lei   WORLD JOURNAL OF GASTROENTEROLOGY

Stress-induced ceramide generation and apoptosis via the phosphorylation and activation of nSMase1 by JNK signaling

(2014) T Yabu et al.   CELL DEATH AND DIFFERENTIATION

Obesity-Induced CerS6-Dependent C16:0 Ceramide Production Promotes Weight Gain and Glucose Intolerance

(2014) Sarah M. Turpin et al.   Cell Metabolism

CerS2 Haploinsufficiency Inhibits β-Oxidation and Confers Susceptibility to Diet-Induced Steatohepatitis and Insulin Resistance

(2014) Suryaprakash Raichur et al.   Cell Metabolism

Caenorhabditis elegans pathways that surveil and defend mitochondria

(2014) Ying Liu et al.   NATURE

Functional role of cardiolipin in mitochondrial bioenergetics

(2013) Giuseppe Paradies et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The mitochondrial unfolded protein response, a conserved stress response pathway with implications in health and disease

(2013) V. Jovaisaite et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

(2013) Charleen T. Chu et al.   NATURE CELL BIOLOGY

Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein

(2012) Weijiao Huang et al.   CELL RESEARCH

Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy

(2012) R David Sentelle et al.   Nature Chemical Biology

Mitophagy Plays an Essential Role in Reducing Mitochondrial Production of Reactive Oxygen Species and Mutation of Mitochondrial DNA by Maintaining Mitochondrial Quantity and Quality in Yeast

(2011) Yusuke Kurihara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sphingosine-1-phosphate signaling and its role in disease

(2011) Michael Maceyka et al.   TRENDS IN CELL BIOLOGY

The Diverse Functions of Oxysterol-Binding Proteins

(2010) Sumana Raychaudhuri et al.   Annual Review of Cell and Developmental Biology

Ceramide and activated Bax act synergistically to permeabilize the mitochondrial outer membrane

(2010) Vidyaramanan Ganesan et al.   APOPTOSIS

Functional implications of sterol transport by the oxysterol-binding protein gene family

(2010) Mike H. Ngo et al.   BIOCHEMICAL JOURNAL

Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration

(2010) Graham M. Strub et al.   FASEB JOURNAL

A Stress-Responsive System for Mitochondrial Protein Degradation

(2010) Jin-Mi Heo et al.   MOLECULAR CELL

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

(2010) Sergio E. Alvarez et al.   NATURE

Challenges in studying phospholipid signaling

(2010) Carsten Schultz   Nature Chemical Biology

G protein-coupled receptors: novel targets for drug discovery in cancer

(2010) Rosamaria Lappano et al.   NATURE REVIEWS DRUG DISCOVERY

Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

(2009) N. C. Hait et al.   SCIENCE

Anti-apoptotic Bcl-2 Family Proteins Disassemble Ceramide Channels

(2008) Leah J. Siskind et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Update of the LIPID MAPS comprehensive classification system for lipids

(2008) Eoin Fahy et al.   JOURNAL OF LIPID RESEARCH

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY