Design and evaluation of bi- and trispecific antibodies targeting multiple filovirus glycoproteins

Mechanistic and Fc requirements for inhibition of Sudan virus entry and in vivo protection by a synthetic antibody

(2017) Daniel Hofmann et al.   IMMUNOLOGY LETTERS

Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques

(2017) Ling Xu et al.   SCIENCE

Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody

(2017) Chad E. Mire et al.   Science Translational Medicine

Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural Ebolavirus Infection

(2016) Andrew I. Flyak et al.   CELL

A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection

(2016)   NEW ENGLAND JOURNAL OF MEDICINE

A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses

(2016) Anna Z. Wec et al.   SCIENCE

Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies

(2016) Zachary A. Bornholdt et al.   mBio

Bispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses

(2016) Julia C. Frei et al.   Scientific Reports

Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site

(2016) Katie A. Howell et al.   Cell Reports

Bispecific antibodies for viral immunotherapy

(2016) Elisabeth K. Nyakatura et al.   Human Vaccines & Immunotherapeutics

Structures of Ebola virus GP and sGP in complex with therapeutic antibodies

(2016) Jesper Pallesen et al.   Nature Microbiology

Discovery of an antibody for pan-ebolavirus therapy

(2016) Wakako Furuyama et al.   Scientific Reports

Structural Basis for Marburg Virus Neutralization by a Cross-Reactive Human Antibody

(2015) Takao Hashiguchi et al.   CELL

Mechanism of Human Antibody-Mediated Neutralization of Marburg Virus

(2015) Andrew I. Flyak et al.   CELL

Mechanism of Binding to Ebola Virus Glycoprotein by the ZMapp, ZMAb, and MB-003 Cocktail Antibodies

(2015) Edgar Davidson et al.   JOURNAL OF VIROLOGY

Macaque Monoclonal Antibodies Targeting Novel Conserved Epitopes within Filovirus Glycoprotein

(2015) Zhen-Yong Keck et al.   JOURNAL OF VIROLOGY

Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses

(2015) Frederick W. Holtsberg et al.   JOURNAL OF VIROLOGY

Ebolavirus Evolution: Past and Present

(2015) Marc-Antoine de La Vega et al.   PLoS Pathogens

Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp

(2014) Xiangguo Qiu et al.   NATURE

Structures of protective antibodies reveal sites of vulnerability on Ebola virus

(2014) Charles D. Murin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic Intervention of Ebola Virus Infection in Rhesus Macaques with the MB-003 Monoclonal Antibody Cocktail

(2013) J. Pettitt et al.   Science Translational Medicine

Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae

(2012) Jens H. Kuhn et al.   ARCHIVES OF VIROLOGY

Ebola virus entry requires the host-programmed recognition of an intracellular receptor

(2012) Emily Happy Miller et al.   EMBO JOURNAL

Protective Efficacy of Neutralizing Monoclonal Antibodies in a Nonhuman Primate Model of Ebola Hemorrhagic Fever

(2012) Andrea Marzi et al.   PLoS One

Postexposure antibody prophylaxis protects nonhuman primates from filovirus disease

(2012) J. M. Dye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Differential Neutralization of Ebolaviruses

(2012) Shridhar Bale et al.   Viruses-Basel

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

(2011) Jan E. Carette et al.   NATURE

A shared structural solution for neutralizing ebolaviruses

(2011) João M Dias et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations

(2010) Jens H. Kuhn et al.   ARCHIVES OF VIROLOGY

A Forward Genetic Strategy Reveals Destabilizing Mutations in the Ebolavirus Glycoprotein That Alter Its Protease Dependence during Cell Entry

(2009) A. C. Wong et al.   JOURNAL OF VIROLOGY

Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor

(2008) Jeffrey E. Lee et al.   NATURE