Site-specificO-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions

Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis

(2017) Lindsey A Lonowski et al.   Nature Protocols

Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents

(2016) Sumeet A. Khetarpal et al.   Cell Metabolism

Recombinant Expression of the Full-length Ectodomain of LDL Receptor-related Protein 1 (LRP1) Unravels pH-dependent Conformational Changes and the Stoichiometry of Binding with Receptor-associated Protein (RAP)

(2016) Camilla De Nardis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Megalin and cubilin in proximal tubule protein reabsorption: from experimental models to human disease

(2016) Rikke Nielsen et al.   KIDNEY INTERNATIONAL

A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2

(2016) Jessika Valero-González et al.   Nature Chemical Biology

Multiple Hepatic Regulatory Variants at the GALNT2 GWAS Locus Associated with High-Density Lipoprotein Cholesterol

(2015) Tamara S. Roman et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Deconstruction of O-glycosylation--GalNAc-T isoforms direct distinct subsets of the O-glycoproteome

(2015) K. T. Schjoldager et al.   EMBO REPORTS

Genome-wide association study of kidney function decline in individuals of European descent

(2015) Mathias Gorski et al.   KIDNEY INTERNATIONAL

Fast and sensitive detection of indels induced by precise gene targeting

(2015) Zhang Yang et al.   NUCLEIC ACIDS RESEARCH

Significance of glycosylation in Notch signaling

(2014) Hideyuki Takeuchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

LDL receptor/lipoprotein recognition: endosomal weakening of ApoB and ApoE binding to the convex face of the LR5 repeat

(2014) Juan Martínez-Oliván et al.   FEBS Journal

A glycogene mutation map for discovery of diseases of glycosylation

(2014) Lars Hansen et al.   GLYCOBIOLOGY

Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysis

(2014) Yun Kong et al.   GLYCOBIOLOGY

Low Density Lipoprotein Receptor Class A Repeats AreO-Glycosylated in Linker Regions

(2014) Nis Borbye Pedersen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The GalNAc-type O-Glycoproteome of CHO Cells Characterized by the SimpleCell Strategy

(2014) Zhang Yang et al.   MOLECULAR & CELLULAR PROTEOMICS

High-efficiency genome editing via 2A-coupled co-expression of fluorescent proteins and zinc finger nucleases or CRISPR/Cas9 nickase pairs

(2014) Katarzyna Duda et al.   NUCLEIC ACIDS RESEARCH

Advantages and Versatility of Fluorescence-Based Methodology to Characterize the Functionality of LDLR and Class Mutation Assignment

(2014) Aitor Etxebarria et al.   PLoS One

Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis

(2014) V. S. Tagliabracci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology

(2013) Catharina Steentoft et al.   EMBO JOURNAL

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Can Mediate Degradation of the Low Density Lipoprotein Receptor-Related Protein 1 (LRP-1)

(2013) Maryssa Canuel et al.   PLoS One

Site-specific protein O-glycosylation modulates proprotein processing — Deciphering specific functions of the large polypeptide GalNAc-transferase gene family

(2012) Katrine T.-B.G. Schjoldager et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells

(2012) K. T.- B. G. Schjoldager et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interaction between the ligand-binding domain of the LDL receptor and the C-terminal domain of PCSK9 is required for PCSK9 to remain bound to the LDL receptor during endosomal acidification

(2011) K. Tveten et al.   HUMAN MOLECULAR GENETICS

Mining the O-glycoproteome using zinc-finger nuclease–glycoengineered SimpleCell lines

(2011) Catharina Steentoft et al.   NATURE METHODS

Structural Insights into the Mechanism of Protein O-Fucosylation

(2011) Erandi Lira-Navarrete et al.   PLoS One

Drosophila Lipophorin Receptors Mediate the Uptake of Neutral Lipids in Oocytes and Imaginal Disc Cells by an Endocytosis-Independent Mechanism

(2011) Esmeralda Parra-Peralbo et al.   PLoS Genetics

Genome-Wide Association Study Using Extreme Truncate Selection Identifies Novel Genes Affecting Bone Mineral Density and Fracture Risk

(2011) Emma L. Duncan et al.   PLoS Genetics

Lipoprotein receptors – an evolutionarily ancient multifunctional receptor family

(2010) Marco Dieckmann et al.   BIOLOGICAL CHEMISTRY

Rescue of Drosophila Melanogaster l(2)35Aa lethality is only mediated by polypeptide GalNAc-transferase pgant35A, but not by the evolutionary conserved human ortholog GalNAc-transferase-T11

(2010) Eric P. Bennett et al.   GLYCOCONJUGATE JOURNAL

Low-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer’s amyloid β-peptide elimination from the brain

(2010) Berislav V. Zlokovic et al.   JOURNAL OF NEUROCHEMISTRY

Structural Basis for Specific Recognition of Reelin by Its Receptors

(2010) Norihisa Yasui et al.   STRUCTURE

Mechanism of LDL binding and release probed by structure-based mutagenesis of the LDL receptor

(2009) Sha Huang et al.   JOURNAL OF LIPID RESEARCH

Receptor-mediated endocytosis in renal proximal tubule

(2009) Erik Ilsø Christensen et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY