Kinesin-2 motors: Kinetics and biophysics

Intraflagellar transport: mechanisms of motor action, cooperation, and cargo delivery

(2017) Bram Prevo et al.   FEBS Journal

Differentiation between Oppositely Oriented Microtubules Controls Polarized Neuronal Transport

(2017) Roderick P. Tas et al.   NEURON

Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load

(2017) Bojan Milic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular origin of the weak susceptibility of kinesin velocity to loads and its relation to the collective behavior of kinesins

(2017) Qian Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microtubule Motors Drive Hedgehog Signaling in Primary Cilia

(2017) Mu He et al.   TRENDS IN CELL BIOLOGY

Moonlighting Motors: Kinesin, Dynein, and Cell Polarity

(2017) Wen Lu et al.   TRENDS IN CELL BIOLOGY

Structural basis of cooperativity in kinesin revealed by 3D reconstruction of a two-head-bound state on microtubules

(2017) Daifei Liu et al.   eLife

Heterodimerization of Kinesin-2 KIF3AB Modulates Entry into the Processive Run

(2016) Clayton D. Albracht et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil

(2016) Rebecca K. Phillips et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct observation of intermediate states during the stepping motion of kinesin-1

(2016) Hiroshi Isojima et al.   Nature Chemical Biology

The cellular mechanisms that maintain neuronal polarity

(2016) Marvin Bentley et al.   NATURE REVIEWS NEUROSCIENCE

Kinesin-2 KIF3AC and KIF3AB Can Drive Long-Range Transport along Microtubules

(2015) Stephanie Guzik-Lendrum et al.   BIOPHYSICAL JOURNAL

The Mechanochemical Cycle of Mammalian Kinesin-2 KIF3A/B under Load

(2015) Johan O.L. Andreasson et al.   CURRENT BIOLOGY

Kinesin superfamily proteins (KIFs): Various functions and their relevance for important phenomena in life and diseases

(2015) Nobutaka Hirokawa et al.   EXPERIMENTAL CELL RESEARCH

Fast or Slow, Either Head Can Start the Processive Run of Kinesin-2 KIF3AC

(2015) Pengwei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Processivity of the Kinesin-2 KIF3A Results from Rear Head Gating and Not Front Head Gating

(2015) Geng-Yuan Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kinetics of nucleotide-dependent structural transitions in the kinesin-1 hydrolysis cycle

(2015) Keith J. Mickolajczyk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinesin, 30 years later: Recent insights from structural studies

(2015) Weiyi Wang et al.   PROTEIN SCIENCE

Kinesin’s Front Head Is Gated by the Backward Orientation of Its Neck Linker

(2015) Merve Yusra Dogan et al.   Cell Reports

Examining kinesin processivity within a general gating framework

(2015) Johan OL Andreasson et al.   eLife

Kinesin-2 KIF3AB Exhibits Novel ATPase Characteristics

(2014) Clayton D. Albracht et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of microtubule motors by tubulin isotypes and post-translational modifications

(2014) Minhajuddin Sirajuddin et al.   NATURE CELL BIOLOGY

Axonal Transport: Cargo-Specific Mechanisms of Motility and Regulation

(2014) Sandra Maday et al.   NEURON

Kinesin processivity is gated by phosphate release

(2014) Bojan Milic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movement

(2014) Luyan Cao et al.   Nature Communications

High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation

(2014) Zhiguo Shang et al.   eLife

Kinesin-2: A Family of Heterotrimeric and Homodimeric Motors with Diverse Intracellular Transport Functions

(2013) Jonathan M. Scholey   Annual Review of Cell and Developmental Biology

The Kinesin-2 Family Member KIF3C Regulates Microtubule Dynamics and Is Required for Axon Growth and Regeneration

(2013) L. F. Gumy et al.   JOURNAL OF NEUROSCIENCE

Structure of a kinesin–tubulin complex and implications for kinesin motility

(2013) Benoît Gigant et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Functional asymmetry in kinesin and dynein dimers

(2012) Katherine C. Rank et al.   BIOLOGY OF THE CELL

Force-Dependent Detachment of Kinesin-2 Biases Track Switching at Cytoskeletal Filament Intersections

(2012) Harry W. Schroeder et al.   BIOPHYSICAL JOURNAL

Cilia functions in development

(2012) Iain A Drummond   CURRENT OPINION IN CELL BIOLOGY

Neck-Linker Length Dependence of Processive Kinesin-5 Motility

(2012) André Düselder et al.   JOURNAL OF MOLECULAR BIOLOGY

Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors

(2012) A. G. Hendricks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinesin Assembly and Movement in Cells

(2011) Kristen J. Verhey et al.   Annual Review of Biophysics

Interhead tension determines processivity across diverse N-terminal kinesins

(2011) S. Shastry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Structure of the Kinesin-1 Motor-Tail Complex Reveals the Mechanism of Autoinhibition

(2011) H. Y. K. Kaan et al.   SCIENCE

The Translocation Selectivity of the Kinesins that Mediate Neuronal Organelle Transport

(2011) Chun-fang Huang et al.   TRAFFIC

Neck Linker Length Determines the Degree of Processivity in Kinesin-1 and Kinesin-2 Motors

(2010) Shankar Shastry et al.   CURRENT BIOLOGY

Motor Coordination via a Tug-of-War Mechanism Drives Bidirectional Vesicle Transport

(2010) Adam G. Hendricks et al.   CURRENT BIOLOGY

Autoinhibition of the kinesin-2 motor KIF17 via dual intramolecular mechanisms

(2010) Jennetta W. Hammond et al.   JOURNAL OF CELL BIOLOGY

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease

(2010) Nobutaka Hirokawa et al.   NEURON

Regulation of a heterodimeric kinesin-2 through an unprocessive motor domain that is turned processive by its partner

(2010) M. Brunnbauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

KAP, the Accessory Subunit of Kinesin-2, Binds the Predicted Coiled-Coil Stalk of the Motor Subunits†

(2009) Harinath Doodhi et al.   BIOCHEMISTRY

Insights into the Mechanical Properties of the Kinesin Neck Linker Domain from Sequence Analysis and Molecular Dynamics Simulations

(2009) Venkatesh Hariharan et al.   Cellular and Molecular Bioengineering

The Processivity of Kinesin-2 Motors Suggests Diminished Front-Head Gating

(2009) Gayatri Muthukrishnan et al.   CURRENT BIOLOGY

Kinesin superfamily motor proteins and intracellular transport

(2009) Nobutaka Hirokawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A mobile kinesin-head intermediate during the ATP-waiting state

(2009) A. B. Asenjo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intramolecular Strain Coordinates Kinesin Stepping Behavior along Microtubules

(2008) Ahmet Yildiz et al.   CELL

Intracellular Transport and Kinesin Superfamily Proteins, KIFs: Structure, Function, and Dynamics

(2008) Nobutaka Hirokawa et al.   PHYSIOLOGICAL REVIEWS