Bromodomain-containing protein 4–independent transcriptional activation by autoimmune regulator (AIRE) and NF-κB
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Bromodomain-containing protein 4–independent transcriptional activation by autoimmune regulator (AIRE) and NF-κB
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 293, Issue 14, Pages 4993-5004
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2018-02-21
DOI
10.1074/jbc.ra117.001518
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Novel BET protein proteolysis-targeting chimera exerts superior lethal activity than bromodomain inhibitor (BETi) against post-myeloproliferative neoplasm secondary (s) AML cells
- (2017) D T Saenz et al. LEUKEMIA
- BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment
- (2017) Georg E. Winter et al. MOLECULAR CELL
- Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications
- (2017) Christopher C. Ebmeier et al. Cell Reports
- CDK9-dependent RNA polymerase II pausing controls transcription initiation
- (2017) Saskia Gressel et al. eLife
- FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator)
- (2016) Wei Shao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells
- (2015) Hideyuki Yoshida et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia (AML)
- (2015) Harald Herrmann et al. Oncotarget
- Release of Positive Transcription Elongation Factor b (P-TEFb) from 7SK Small Nuclear Ribonucleoprotein (snRNP) Activates Hexamethylene Bisacetamide-inducible Protein (HEXIM1) Transcription
- (2014) Pingyang Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SUMOylation of GPS2 protein regulates its transcription-suppressing function
- (2014) Hailian Bi et al. MOLECULAR BIOLOGY OF THE CELL
- NF-κB Directs Dynamic Super Enhancer Formation in Inflammation and Atherogenesis
- (2014) Jonathan D. Brown et al. MOLECULAR CELL
- Transcriptional Control by NF-κB: Elongation in Focus
- (2013) Gil Diamant et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
- (2013) Jakob Lovén et al. CELL
- The Mechanism of Tissue-Restricted Antigen Gene Expression by AIRE
- (2013) K. Zumer et al. JOURNAL OF IMMUNOLOGY
- BRD4 Coordinates Recruitment of Pause Release Factor P-TEFb and the Pausing Complex NELF/DSIF To Regulate Transcription Elongation of Interferon-Stimulated Genes
- (2013) M. C. Patel et al. MOLECULAR AND CELLULAR BIOLOGY
- Bromodomain Protein Brd4 Associated with Acetylated Chromatin Is Important for Maintenance of Higher-order Chromatin Structure
- (2012) Ranran Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bromodomain and Extra-terminal (BET) Bromodomain Inhibition Activate Transcription via Transient Release of Positive Transcription Elongation Factor b (P-TEFb) from 7SK Small Nuclear Ribonucleoprotein
- (2012) Koen Bartholomeeusen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Unmodified Histone H3K4 and DNA-Dependent Protein Kinase Recruit Autoimmune Regulator to Target Genes
- (2012) K. Zumer et al. MOLECULAR AND CELLULAR BIOLOGY
- PKC phosphorylates HEXIM1 and regulates P-TEFb activity
- (2012) Koh Fujinaga et al. NUCLEIC ACIDS RESEARCH
- BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
- (2011) Jake E. Delmore et al. CELL
- Discovery and Characterization of Small Molecule Inhibitors of the BET Family Bromodomains
- (2011) Chun-wa Chung et al. JOURNAL OF MEDICINAL CHEMISTRY
- Patient mutation in AIRE disrupts P-TEFb binding and target gene transcription
- (2011) Kristina Žumer et al. NUCLEIC ACIDS RESEARCH
- 7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcription
- (2011) B. Matija Peterlin et al. Wiley Interdisciplinary Reviews-RNA
- SIRT2 regulates NF- B-dependent gene expression through deacetylation of p65 Lys310
- (2010) K. M. Rothgiesser et al. JOURNAL OF CELL SCIENCE
- Eukaryotic transcription initiation
- (2009) Shankarling Krishnamurthy et al. CURRENT BIOLOGY
- Regulatory T cells exert checks and balances on self tolerance and autoimmunity
- (2009) Kajsa Wing et al. NATURE IMMUNOLOGY
- Structural Basis and Binding Properties of the Second Bromodomain of Brd4 with Acetylated Histone Tails†‡
- (2008) Ying Liu et al. BIOCHEMISTRY
- Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire
- (2008) Maureen A. Su et al. JOURNAL OF CLINICAL INVESTIGATION
- RelA Ser276 Phosphorylation Is Required for Activation of a Subset of NF- B-Dependent Genes by Recruiting Cyclin-Dependent Kinase 9/Cyclin T1 Complexes
- (2008) D. E. Nowak et al. MOLECULAR AND CELLULAR BIOLOGY
- Brd4 Coactivates Transcriptional Activation of NF- B via Specific Binding to Acetylated RelA
- (2008) B. Huang et al. MOLECULAR AND CELLULAR BIOLOGY
- DNA-PK contributes to the phosphorylation of AIRE: Importance in transcriptional activity
- (2007) Ingrid Liiv et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started