Transforming growth factor β2 (TGFβ2) signaling plays a key role in glucocorticoid-induced ocular hypertension

The many faces of the trabecular meshwork cell

(2017) W. Daniel Stamer et al.   EXPERIMENTAL EYE RESEARCH

Increased synthesis and deposition of extracellular matrix proteins leads to endoplasmic reticulum stress in the trabecular meshwork

(2017) Ramesh B. Kasetti et al.   Scientific Reports

Human trabecular meshwork cells express BMP antagonist mRNAs and proteins

(2016) Tara Tovar-Vidales et al.   EXPERIMENTAL EYE RESEARCH

Animal models of glucocorticoid-induced glaucoma

(2015) Darryl R. Overby et al.   EXPERIMENTAL EYE RESEARCH

The mechanism and significance of synergistic induction of the expression of plasminogen activator inhibitor-1 by glucocorticoid and transforming growth factor beta in human ovarian cancer cells

(2015) Xiao-yu Pan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Ocular-specific ER stress reduction rescues glaucoma in murine glucocorticoid-induced glaucoma

(2014) Gulab S. Zode et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of the Alternatively Spliced Glucocorticoid Receptor Isoform GRβ in Steroid Responsiveness and Glaucoma

(2014) Ankur Jain et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Global Prevalence of Glaucoma and Projections of Glaucoma Burden through 2040

(2014) Yih-Chung Tham et al.   OPHTHALMOLOGY

Smad3 is necessary for transforming growth factor-beta2 induced ocular hypertension in mice

(2013) Colleen M. McDowell et al.   EXPERIMENTAL EYE RESEARCH

Calreticulin Regulates Transforming Growth Factor-β-stimulated Extracellular Matrix Production

(2013) Kurt A. Zimmerman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucocorticoids Recruit Tgfbr3 and Smad1 to Shift Transforming Growth Factor-β Signaling from the Tgfbr1/Smad2/3 Axis to the Acvrl1/Smad1 Axis in Lung Fibroblasts

(2013) Julian T. Schwartze et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic reticulum stress as a pro-fibrotic stimulus

(2012) Harikrishna Tanjore et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Transforming growth factor-beta2 utilizes the canonical Smad-signaling pathway to regulate tissue transglutaminase expression in human trabecular meshwork cells

(2011) Tara Tovar-Vidales et al.   EXPERIMENTAL EYE RESEARCH

Latent TGF-β structure and activation

(2011) Minlong Shi et al.   NATURE

Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs

(2011) W. E. Lawson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucocorticoid enhances hypoxia- and/or transforming growth factor-β-induced plasminogen activator inhibitor-1 production in human proximal renal tubular cells

(2010) Hideki Kimura et al.   Clinical and Experimental Nephrology

Endoplasmic reticulum stress in liver disease

(2010) Harmeet Malhi et al.   JOURNAL OF HEPATOLOGY

Signaling cross-talk between TGF-β/BMP and other pathways

(2008) Xing Guo et al.   CELL RESEARCH

The role of steroids in outflow resistance

(2008) Abbot F. Clark et al.   EXPERIMENTAL EYE RESEARCH

ATF4 is an oxidative stress–inducible, prodeath transcription factor in neurons in vitro and in vivo

(2008) Philipp S. Lange et al.   JOURNAL OF EXPERIMENTAL MEDICINE