Low-density lipoprotein receptor–related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression

Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis

(2017) Sachin H. Patel et al.   GASTROENTEROLOGY

LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis

(2017) Xunde Xian et al.   eLife

Chronic Over-expression of Fibroblast Growth Factor 21 Increases Bile Acid Biosynthesis by Opposing FGF15/19 Action

(2017) Jun Zhang et al.   EBioMedicine

Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis

(2016) Xiaobo Wang et al.   Cell Metabolism

LRP1 Protein Deficiency Exacerbates Palmitate-induced Steatosis and Toxicity in Hepatocytes

(2016) Allyson N. Hamlin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholesterol 7α-hydroxylase-deficient mice are protected from high-fat/high-cholesterol diet-induced metabolic disorders

(2016) Jessica M. Ferrell et al.   JOURNAL OF LIPID RESEARCH

Low-Density Lipoprotein Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and Hepatic Steatosis

(2016) Yinyuan Ding et al.   EBioMedicine

Non-alcoholic fatty liver disease: a massive problem

(2013) C. P. Day   CLINICAL MEDICINE

Synergistic interaction of dietary cholesterol and dietary fat in inducing experimental steatohepatitis

(2012) Christopher Savard et al.   HEPATOLOGY

Low Level of Low-Density Lipoprotein Receptor-Related Protein 1 Predicts an Unfavorable Prognosis of Hepatocellular Carcinoma after Curative Resection

(2012) Xiao-Yong Huang et al.   PLoS One

Characterization of macroautophagic flux in vivo using a leupeptin-based assay

(2011) Jeffrey Haspel et al.   Autophagy

Hepatic Deficiency of Low Density Lipoprotein Receptor-related Protein-1 Reduces High Density Lipoprotein Secretion and Plasma Levels in Mice

(2011) Joshua E. Basford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice

(2011) Savitha Subramanian et al.   JOURNAL OF LIPID RESEARCH

Secondary causes of nonalcoholic fatty liver disease

(2011) Jacob M. Kneeman et al.   Therapeutic Advances in Gastroenterology

Characterization of two F4/80-positive Kupffer cell subsets by their function and phenotype in mice

(2010) Manabu Kinoshita et al.   JOURNAL OF HEPATOLOGY

Hepatocellular Carcinoma – Epidemiological Trends and Risk Factors

(2009) Kerstin Schütte et al.   DIGESTIVE DISEASES

Association between dietary nutrient composition and the incidence of cirrhosis or liver cancer in the united states population

(2009) George N. Ioannou et al.   HEPATOLOGY

LRP1 Controls cPLA2 Phosphorylation, ABCA1 Expression and Cellular Cholesterol Export

(2009) Li Zhou et al.   PLoS One

Mallory–Denk-bodies: Lessons from keratin-containing hepatic inclusion bodies

(2008) P. Strnad et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

(2008) Kristiaan Wouters et al.   HEPATOLOGY

Expanding functions of lipoprotein receptors

(2008) Joachim Herz et al.   JOURNAL OF LIPID RESEARCH

LDL Receptor-Related Protein 1: Unique Tissue-Specific Functions Revealed by Selective Gene Knockout Studies

(2008) Anna P. Lillis et al.   PHYSIOLOGICAL REVIEWS