Journal
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 22, Issue 1, Pages 1-16Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2018.1492565
Keywords
Eupatilin; anti-cancer; anti-inflammatory; anti-oxidant; medicinal plants; flavone
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Eupatilin (5,7-dihydroxy-3 ',4 ',6-trimethoxyflavone) is a pharmacologically active flavone which has been isolated from a variety of medicinal plants. Eupatilin is known to possess various pharmacological properties such as anti-cancer, anti-oxidant, and anti-inflammatory. It is speculated that eupatilin could be subjected to structural optimization for the synthesis of derivative analogs to reinforce its efficacy, to minimize toxicity, and to optimize absorption profiles, which will ultimately lead towards potent drug candidates. Although, reported data acclaim multiple pharmacological activities of eupatilin but further experimentations on its molecular mechanism of action are yet mandatory to elucidate full spectrum of its pharmacological activities.
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