Trichloroethylene exposure results in the phosphorylation of histone H2AX in a human hepatic cell line through cytochrome P450 2E1-mediated oxidative stress

1,2-Dichloropropane generates phosphorylated histone H2AX via cytochrome P450 2E1-mediated metabolism

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The role of reactive oxygen species (ROS) and cytochrome P-450 2E1 in the generation of carcinogenic etheno-DNA adducts

(2014) Kirsten Linhart et al.   Redox Biology

Trichloroethylene: Mechanistic, epidemiologic and other supporting evidence of carcinogenic hazard

(2013) Ivan Rusyn et al.   PHARMACOLOGY & THERAPEUTICS

Phosphorylation of Histone H2AX Is a Powerful Tool for Detecting Chemical Photogenotoxicity

(2011) Tatsushi Toyooka et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Trichloroethylene and Cancer: Systematic and Quantitative Review of Epidemiologic Evidence for Identifying Hazards

(2011) Cheryl Siegel Scott et al.   International Journal of Environmental Research and Public Health

γH2AX: a sensitive molecular marker of DNA damage and repair

(2010) L-J Mah et al.   LEUKEMIA

Role of oxidatively induced DNA lesions in human pathogenesis

(2010) Olga A. Sedelnikova et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

H2AX: functional roles and potential applications

(2009) Jennifer S. Dickey et al.   CHROMOSOMA

Possible involvement of oxidative stress in trichloroethylene-induced genotoxicity in human HepG2 cells

(2008) Cunli Hu et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

CYP2E1 and oxidative liver injury by alcohol

(2007) Yongke Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE