Zinc Exacerbates Tau Pathology in a Tau Mouse Model

The Effect of Metals on Spatial Memory in a Transgenic Mouse Model of Alzheimer's Disease

(2018) Angela M. Railey et al.   JOURNAL OF ALZHEIMERS DISEASE

The Metal Theory of Alzheimer's Disease

(2018) Ashley I. Bush   JOURNAL OF ALZHEIMERS DISEASE

Disruption of normal circadian clock function in a mouse model of tauopathy

(2017) Korey Stevanovic et al.   EXPERIMENTAL NEUROLOGY

Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer’s disease

(2017) Ramesh Kandimalla et al.   HUMAN MOLECULAR GENETICS

Extracellular Zn2+Is Essential for Amyloid β1–42-Induced Cognitive Decline in the Normal Brain and Its Rescue

(2017) Atsushi Takeda et al.   JOURNAL OF NEUROSCIENCE

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

(2017) Yang Shi et al.   NATURE

The Effects of Enhanced Zinc on Spatial Memory and Plaque Formation in Transgenic Mice

(2017) David H. Linkous et al.   JOURNAL OF ALZHEIMERS DISEASE

Position on zinc delivery to olfactory nerves in intranasal insulin phase I–III clinical trials

(2015) A. Hamidovic   Contemporary Clinical Trials

Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model

(2015) Casey Cook et al.   HUMAN MOLECULAR GENETICS

Metal chaperones prevent zinc-mediated cognitive decline

(2015) Paul A. Adlard et al.   NEUROBIOLOGY OF DISEASE

Effect size of memory deficits in mice with adult-onset P301L tau expression

(2014) Holly C. Hunsberger et al.   BEHAVIOURAL BRAIN RESEARCH

Severe amygdala dysfunction in a MAPT transgenic mouse model of frontotemporal dementia

(2014) Casey Cook et al.   NEUROBIOLOGY OF AGING

Zinc Binding Directly Regulates Tau Toxicity Independent of Tau Hyperphosphorylation

(2014) Yunpeng Huang et al.   Cell Reports

Spatial memory deficits in a mouse model of late-onset Alzheimer’s disease are caused by zinc supplementation and correlate with amyloid-beta levels

(2014) Jane M. Flinn et al.   Frontiers in Aging Neuroscience

Modulation of tau phosphorylation by environmental copper

(2014) Kellen Voss et al.   Translational Neurodegeneration

Luteolin Reduces Zinc-Induced Tau Phosphorylation at Ser262/356 in an ROS-Dependent Manner in SH-SY5Y Cells

(2012) Futao Zhou et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Synaptic Released Zinc Promotes Tau Hyperphosphorylation by Inhibition of Protein Phosphatase 2A (PP2A)

(2012) Xu-Ying Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trans-Synaptic Spread of Tau Pathology In Vivo

(2012) Li Liu et al.   PLoS One

The Zinc Dyshomeostasis Hypothesis of Alzheimer's Disease

(2012) Travis J. A. Craddock et al.   PLoS One

Human P301L-Mutant Tau Expression in Mouse Entorhinal-Hippocampal Network Causes Tau Aggregation and Presynaptic Pathology but No Cognitive Deficits

(2012) Julie A. Harris et al.   PLoS One

A peculiar constellation of tau pathology defines a subset of dementia in the elderly

(2011) Gabor G. Kovacs et al.   ACTA NEUROPATHOLOGICA

Free zinc ions outside a narrow concentration range are toxic to a variety of cells in vitro

(2010) Rebecca A Bozym et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Alterations in fear response and spatial memory in pre- and post-natal zinc supplemented rats: Remediation by copper

(2010) Angela M. Railey et al.   PHYSIOLOGY & BEHAVIOR

Chronic copper exposure exacerbates both amyloid and tau pathology and selectively dysregulates cdk5 in a mouse model of AD

(2009) Masashi Kitazawa et al.   JOURNAL OF NEUROCHEMISTRY

Disrupted sleep and circadian patterns in frontotemporal dementia

(2008) K. N. Anderson et al.   EUROPEAN JOURNAL OF NEUROLOGY

Effect of Physical Activity on Cognitive Function in Older Adults at Risk for Alzheimer Disease

(2008) Nicola T. Lautenschlager et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Setting Clock Speed in Mammals: The CK1ɛ tau Mutation in Mice Accelerates Circadian Pacemakers by Selectively Destabilizing PERIOD Proteins

(2008) Qing-Jun Meng et al.   NEURON