Article
Nursing
Sangwoo Ahn, Michelle A. Mathiason, Fang Yu
Summary: Depressive symptoms were predictive of lower episodic memory and executive function. Nurses should pay attention to depressive symptoms in older adults with SCD, as managing depressive symptoms may help prevent cognitive decline more typical of early Alzheimer's dementia.
JOURNAL OF NURSING SCHOLARSHIP
(2021)
Article
Psychology, Multidisciplinary
Hilary J. Traut, Ryan M. Guild, Yuko Munakata
Summary: Despite inconsistent benefits of cognitive training, evidence suggests that poor performers may benefit the most, showing a compensatory effect. The association between individual differences in baseline cognitive ability and training gains may depend on the specific cognitive domain and training approach. Further research is needed to better understand how cognitive trainings work and for whom.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Psychiatry
Mirjam Stieger, Margie E. Lachman
Summary: Increasing cognitive activity is important for reducing declines in executive functioning, especially among individuals with lower educational attainment.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychology, Multidisciplinary
David J. Libon, Emily Frances Matusz, Stephanie Cosentino, Catherine C. Price, Rod Swenson, Meagan Vermeulen, Terrie Beth Ginsberg, Adaora Obiageli Okoli-Umeweni, Leonard Powell, Robert Nagele, Sean Tobyne, Joyce Rios Gomes-Osman, Alvaro Pascual-Leone
Summary: The Core Cognitive Evaluation (CCE), administered and scored using an iPad, is a powerful neurocognitive assessment tool for screening patients' neurocognitive impairment and psychological distress in ambulatory medical care settings. It is linked with patients' self-reported concerns about memory and cardiovascular risks.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Biology
Lyndsey Aponik-Gremillion, Yvonne Y. Chen, Eleonora Bartoli, Seth R. Koslov, Hernan G. Rey, Kevin S. Weiner, Daniel Yoshor, Benjamin Y. Hayden, Sameer A. Sheth, Brett L. Foster
Summary: The role of the posterior cingulate cortex (PCC) in cognition is still not clear, even though it has been implicated in psychiatric and neurological diseases. Previous studies have shown conflicting views on the function of PCC in humans and non-human primates. This study provides electrophysiological data from human PCC, revealing different functional types and enhancing our understanding of PCC function.
Article
Geriatrics & Gerontology
Joukje M. Oosterman, Michelle G. Jansen, Erik J. A. Scherder, Roy P. C. Kessels
Summary: The study aimed to investigate whether cognitive reserve still moderates the relationship between age and cognitive functioning in the old-old. Results show that as the level of cognitive reserve increases, the negative relationship between age and cognitive performance in the old-old adults is reduced.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2021)
Article
Clinical Neurology
Juan Luis Sanchez-Sanchez, Kelly V. Giudici, Sophie Guyonnet, Julien Delrieu, Yan Li, Randall J. Bateman, Angelo Parini, Bruno Vellas, Philipe de Souto Barreto
Summary: Baseline plasma MCP-1 levels were associated with longitudinal declines in overall cognitive and episodic memory performance in older adults over a 4-year follow-up. Interaction between plasma MCP-1 and A beta(42/40) may determine cognitive decline, especially in individuals with amyloid plaques. Further research should clarify the precise mechanism of this association.
ALZHEIMERS RESEARCH & THERAPY
(2022)
Article
Behavioral Sciences
Elizabeth McManus, Deborah Talmi, Hamied Haroon, Nils Muhlert
Summary: The impact of psychosocial stress on episodic memory and related cognitive abilities is still unclear. Some studies found a small positive effect of post-learning psychosocial stress with a long retention interval, but no other effects of psychosocial stress were seen. Re-analysis showed no significant effect of psychosocial stress on episodic memory, highlighting potentially different effects between stressor types. Psychosocial stress also had a moderately different effect when emotional vs. neutral stimuli were compared. Additionally, psychosocial stress decreased performance on executive function, but not working memory tasks.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Geriatrics & Gerontology
Geoffroy Gagliardi, Patrizia Vannini
Summary: This study investigates the mechanisms of awareness loss in Alzheimer's Disease, and finds that dysfunction in episodic memory is primarily responsible for the effect of amyloid on awareness.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Clinical Neurology
Melanie Fortier, Christian-Alexandre Castellano, Valerie St-Pierre, Etienne Myette-Cote, Francis Langlois, Maggie Roy, Marie-Christine Morin, Christian Bocti, Tamas Fulop, Jean-Philippe Godin, Carla Delannoy, Bernard Cuenoud, Stephen C. Cunnane
Summary: Supplementation with ketogenic medium chain triglyceride (kMCT) drink significantly improved cognitive outcomes in mild cognitive impairment (MCI), possibly by increasing blood ketone levels. These data support further evaluation of MCI progression to Alzheimer's disease.
ALZHEIMERS & DEMENTIA
(2021)
Article
Public, Environmental & Occupational Health
Anying Bai, Liyuan Tao, Jia Huang, Jing Tao, Jue Liu
Summary: Physical activity is associated with better episodic memory function and may prevent potential decline in diabetic patients. No significant association was found between physical activity and executive function.
Article
Geriatrics & Gerontology
Ruijia Chen, Jennifer Weuve, Supriya Misra, Adolfo Cuevas, Laura D. Kubzansky, David R. Williams
Summary: This study found that racial disparities in executive function and episodic memory in middle-aged and older adults can be partly explained by cumulative stress exposures across the life course.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2022)
Article
Pharmacology & Pharmacy
Jonathan C. Broder, Joanne Ryan, Raj C. Shah, Jessica E. Lockery, Suzanne G. Orchard, Julia F. M. Gilmartin-Thomas, Michelle A. Fravel, Alice J. Owen, Robyn L. Woods, Rory Wolfe, Elsdon Storey, Anne M. Murray, Michael E. Ernst
Summary: The study found that anticholinergic burden is associated with cognitive decline in older adults, particularly affecting executive function and memory function.
Review
Neurosciences
Samaneh Nakhaee, Alireza Kooshki, Ali Hormozi, Aref Akbari, Omid Mehrpour, Khadijeh Farrokhfall
Summary: This study aimed to systematically review the relationship between cinnamon and its key components in memory and learning. The results showed that cinnamon significantly improves cognitive function, including memory and learning. Cinnamon and its bioactive compounds can influence brain function and affect behavioral characteristics.
NUTRITIONAL NEUROSCIENCE
(2023)
Article
Public, Environmental & Occupational Health
Ruijia Chen, David R. Williams, Kristen Nishimi, Natalie Slopen, Laura D. Kubzansky, Jennifer Weuve
Summary: This study found that cumulative stress exposure is associated with poorer cognitive function and faster cognitive decline. Both high stress in childhood and adulthood were linked to lower executive function and episodic memory. However, there was little evidence to suggest that the rate of decline in cognitive function differed across levels of stress exposure.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Psychology, Clinical
Daniel Camilo Aguirre-Acevedo, Fabian Jaimes-Barragan, Eliana Henao, Victoria Tirado, Claudia Munoz, Eric M. Reiman, Pierre N. Tariot, Jessica B. Langbaum, Francisco Lopera
INTERNATIONAL PSYCHOGERIATRICS
(2016)
Article
Clinical Neurology
Daniel C. Aguirre-Acevedo, Francisco Lopera, Eliana Henao, Victoria Tirado, Claudia Munoz, Margarita Giraldo, Shrikant I. Bangdiwala, Eric M. Reiman, Pierre N. Tariot, Jessica B. Langbaum, Yakeel T. Quiroz, Fabian Jaimes
Article
Geriatrics & Gerontology
Stefanie C. Biehl, Melanie Andersen, Gordon D. Waiter, Karin S. Pilz
NEUROBIOLOGY OF AGING
(2017)
Article
Clinical Neurology
Daniel J. Norton, Rebecca Amariglio, Hillary Protas, Kewei Chen, Daniel C. Aguirre-Acevedo, Brendan Pulsifer, Gabriel Castrillon, Victoria Tirado, Claudia Munoz, Pierre Tariot, Jessica B. Langbaum, Eric M. Reiman, Francisco Lopera, Reisa A. Sperling, Yakeel T. Quiroz
Article
Clinical Neurology
Yakeel T. Quiroz, Reisa A. Sperling, Daniel J. Norton, Ana Baena, Joseph F. Arboleda-Velasquez, Danielle Cosio, Aaron Schultz, Molly Lapoint, Edmarie Guzman-Velez, John B. Miller, Leo A. Kim, Kewei Chen, Pierre N. Tariot, Francisco Lopera, Eric M. Reiman, Keith A. Johnson
Article
Clinical Neurology
Bernard J. Hanseeuw, Francisco Lopera, Reisa A. Sperling, Daniel J. Norton, Edmarie Guzman-Velez, Ana Baena, Enmanuelle Pardilla-Delgado, Aaron P. Schultz, Jennifer Gatchel, David Jin, Kewei Chen, Eric M. Reiman, Keith A. Johnson, Yakeel T. Quiroz
ALZHEIMERS RESEARCH & THERAPY
(2019)
Article
Clinical Neurology
Valeria L. Torres, Clara Vila-Castelar, Yamile Bocanegra, Ana Baena, Edmarie Guzman-Velez, Daniel C. Aguirre-Acevedo, Victoria Tirado, Claudia Munoz, Eliana Henad, Sonia Moreno, Margarita Giraldo, Natalia Acosta, Silvia Rios Romenets, Jessica B. Langbaum, William Cho, Eric M. Reiman, Pierre N. Tariot, Monica Rosselli, Yakeel T. Quiroz, Francisco Lopera
Summary: Neuropsychologists face challenges in assessing Spanish-speaking individuals due to limited normative data. A comprehensive set of norms stratified by age and education was developed for a Spanish neuropsychological test battery. Cognitive performance was found to be associated with age and education, but not with sex, based on a retrospective study of 2,673 cognitively unimpaired individuals.
APPLIED NEUROPSYCHOLOGY-ADULT
(2021)
Article
Clinical Neurology
Silvia Rios-Romenets, Francisco Lopera, Kaycee M. Sink, Nan Hu, Qinshu Lian, Heather Guthrie, Jillian Smith, William Cho, Howard Mackey, Jessica B. Langbaum, Ronald G. Thomas, Margarita Giraldo-Chica, Carlos Tobon, Natalia Acosta-Baena, Claudia Munoz, Paula Ospina, Victoria Tirado, Eliana Henao, Yamile Bocanegra, Kewei Chen, Yi Su, Dhruman Goradia, Pradeep Thiyyagura, Paul S. VanGilder, Ji Luo, Valentina Ghisays, Wendy Lee, Michael H. Malek-Ahmadi, Hillary D. Protas, Yinghua Chen, Yakeel T. Quiroz, Eric M. Reiman, Pierre N. Tariot
ALZHEIMERS & DEMENTIA
(2020)
Article
Medicine, General & Internal
Patrizia Vannini, Bernard J. Hanseeuw, Jennifer R. Gatchel, Sietske A. M. Sikkes, Diana Alzate, Yesica Zuluaga, Sonia Moreno, Luis Mendez, Ana Baena, Paula Ospina-Lopera, Victoria Tirado, Eliana Henao, Natalia Acosta-Baena, Margarita Giraldo, Francisco Lopera, Yakeel T. Quiroz
Article
Clinical Neurology
Jairo E. Martinez, Enmanuelle Pardilla-Delgado, Edmarie Guzman-Velez, Clara Vila-Castelar, Rebecca Amariglio, Jennifer Gatchel, Daniel C. Aguirre-Acevedo, Yamile Bocanegra, Ana Baena, Eliana Henao, Victoria Tirado, Claudia Munoz, Margarita Giraldo-Chica, Francisco Lopera, Yakeel T. Quiroz
Summary: Research findings suggest that in ADAD patients, women are more likely to experience cognitive decline compared to men, and female SCD is more strongly associated with worse memory performance. Therefore, future studies should consider sex differences when recruiting samples and conducting clinical trials.
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY
(2022)
Article
Clinical Neurology
Clara Vila-Castelar, Pierre N. Tariot, Kaycee M. Sink, David Clayton, Jessica B. Langbaum, Ronald G. Thomas, Yinghua Chen, Yi Su, Kewei Chen, Nan Hu, Margarita Giraldo-Chica, Carlos Tobon, Natalia Acosta-Baena, Ernesto Luna, Marisol Londono, Paula Ospina, Victoria Tirado, Claudia Munoz, Eliana Henao, Yamile Bocanegra, Sergio Alvarez, Silvia Rios-Romenets, Valentina Ghisays, Dhruman Goradia, Wendy Lee, Ji Luo, Michael H. Malek-Ahmadi, Hillary D. Protas, Francisco Lopera, Eric M. Reiman, Yakeel T. Quiroz
Summary: This study examined the effect of sex on pathology, neurodegeneration, and memory in cognitively-unimpaired individuals with and without the Presenilin-1 (PSEN1) E280A mutation. The results suggest that females may have greater cognitive resilience to AD pathology and neurodegeneration than males.
ALZHEIMERS & DEMENTIA
(2022)
Article
Psychology, Clinical
Lauren A. Rutter, Daniel J. Norton, Bonnie S. Brown, Timothy A. Brown
COGNITIVE THERAPY AND RESEARCH
(2019)
Review
Clinical Neurology
J. T. Fuller, A. Cronin-Golomb, J. R. Gatchel, D. J. Norton, E. Guzman-Velez, H. I. L. Jacobs, B. Hanseeuw, E. Pardilla-Delgado, A. Artola, A. Baena, Y. Bocanegra, K. S. Kosik, K. Chen, P. N. Tariot, K. Johnson, R. A. Sperling, E. M. Reiman, F. Lopera, Y. T. Quiroz
JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE
(2019)