Journal
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Volume 66, Issue 18, Pages 4581-+Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.jafc.8b00493
Keywords
polysaccharide; quality control; method repeatability; bioavailability; phagocytos
Funding
- Hong Kong Special Administrative Region (HKSAR) Innovation and Technology Fund (ITF) [ITS/311/09]
- General Research Fund [12100615, 22100014]
- Health Medical Research Fund [11122531, 14150521]
- National Natural Sciences Foundation in China [81473341]
- Hong Kong Baptist University [Research Committee (RC)] [MPCF-001-2014/2015, RC-IRMS/14-15/06, FRG1/16-17/032, FRG2/16-17/002]
Ask authors/readers for more resources
Natural polysaccharides are attracting increasing attention from food and pharmaceutical industries for their wide range of valuable biological activities. However, the poor repeatability of the methods used in sample preparation and chemical characterization is hampering both research and product development. The unstandardized quality, in turn, undermines efforts to understand the mechanism by which they work via oral dose, which is essential to realize the full beneficial potential of polysaccharides. Some scientists believe polysaccharides work by direct gut absorption; however, increasing evidence points to the gut microbiome and intestinal Peyer's patches as holding the keys to how they work.
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