Article
Clinical Neurology
Jeroen C. de Jonge, Diederik van de Beek, Patrick Lyden, Marian C. Brady, Philip M. Bath, H. Bart van der Worp
Summary: The occurrence of pneumonia after stroke is associated with a higher risk of poor outcome or death. Pneumonia mostly occurs within the first week after stroke, with the peak incidence on the third day. The most optimal period to assess pneumonia prevention strategies is within the first 4 days after stroke.
Article
Microbiology
Audet-Gilbert Emie, Sylvain Francois-etienne, Bouslama Sidki, Derome Nicolas
Summary: The study demonstrates that in the interaction between clownfish and anemone, both remote and physical contact lead to a gradual convergence of their skin microbiota, which persists even after separation. The restructuring of microbiota may be associated with the recruitment of specific bacterial strains.
Article
Endocrinology & Metabolism
Smadar Shilo, Anastasia Godneva, Marianna Rachmiel, Tal Korem, Yuval Bussi, Dmitry Kolobkov, Tal Karady, Noam Bar, Bat Chen Wolf, Yitav Glantz-Gashai, Michal Cohen, Nehama Zuckerman Levin, Naim Shehadeh, Noah Gruber, Neriya Levran, Shlomit Koren, Adina Weinberger, Orit Pinhas-Hamiel, Eran Segal
Summary: This study identified a distinct gut microbial signature in adults with longstanding T1D and associations between microbial taxa, metabolic pathways, and glycemic control indices. Further mechanistic studies are needed to determine the role of these bacteria in potential therapeutic strategies.
Article
Agriculture, Dairy & Animal Science
Siriluck Ponsuksili, Frieder Hadlich, Alvaro Perdomo-Sabogal, Henry Reyer, Michael Oster, Nares Trakooljul, Muhammad Arsalan Iqbal, Sonja Schmucker, Volker Stefanski, Christoph Roth, Amelia Camarinha Silva, Korinna Huber, Vera Sommerfeld, Markus Rodehutscord, Klaus Wimmers
Summary: Aggregation of various data sets provides a comprehensive understanding of lifelong adaptation processes in laying hens. Two strains of laying hens, LB and LSL, were analyzed at different ages, revealing strain-specific and stage-specific biosignatures, including molecular pathways. Although the strains performed similarly, they showed differences in immunological and metabolic functions, as well as gut-microbiota interactions, indicating different strategies under high performance conditions. The integrative analysis not only provides insights into functional biodiversity, but also offers guidance for further manual review of the data.
Article
Biotechnology & Applied Microbiology
Katarzyna Pauter-Iwicka, Viorica Railean, Michal Zloch, Pawel Pomastowski, Malgorzata Szultka-Mlynska, Dominika Blonska, Wojciech Kupczyk, Boguslaw Buszewski
Summary: In this study, the MALDI-TOF MS technique was used to rapidly identify the salivary microbiome. The results showed significant changes in the composition of the salivary microbiota under different antibiotic therapy. This approach highlighted the potential of developing faster diagnostic methods for diseases at the cellular level.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Immunology
Dong Hong Yu, Niu Ying, Zhang Hong Lian, Ye Qi Fa
Summary: The study revealed significant variations in gut microbiota and metabolites following renal transplantation, with relatively stable and reasonable concordance in patients with uremia. Distinct microbial compositions and metabolites were observed in patients after transplantation.
MICROBIAL PATHOGENESIS
(2021)
Article
Multidisciplinary Sciences
Michael Sieber, Arne Traulsen, Hinrich Schulenburg, Angela E. Douglas
Summary: The prevalence of specific microbes in a host population can increase even when they do not provide specific benefits to the host, especially when there is overlap in their lifecycles and they share dispersal routes. This suggests that host enrichment alone is not a reliable indicator of beneficial host-microbe interactions, but increased time spent associated with a host can lead to new selection conditions, potentially favoring microbial adaptations towards a host-associated lifestyle and laying the foundation for the evolution of mutually beneficial coevolved symbioses.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Biochemistry & Molecular Biology
Yue Su, Shasha Cheng, Yixin Ding, Linge Wang, Mingshuang Sun, Chaoxin Man, Yu Zhang, Yujun Jiang
Summary: This study investigated the effects of two polysaccharides (HEP and FHEP) extracted from fermented Hericium erinaceus on the intestinal barrier in cell and mice models. The results showed that polysaccharides had a protective effect against acrylamide-induced injury in IEC-6 cell and enhanced the intestinal barrier function in mice by improving cytokines level, tight junction and mucin expression, and gut microbiota.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Clinical Neurology
Olivia Foesleitner, Benjamin Sigl, Victor Schmidbauer, Karl-Heinz Nenning, Ekaterina Pataraia, Lisa Bartha-Doering, Christoph Baumgartner, Susanne Pirker, Doris Moser, Michelle Schwarz, Johannes A. Hainfellner, Thomas Czech, Christian Dorfer, Georg Langs, Daniela Prayer, Silvia Bonelli, Gregor Kasprian
Summary: Epilepsy surgery is a recommended treatment for drug-resistant temporal lobe epilepsy, but can lead to postoperative language impairment. This study found widespread bilateral remodeling of language networks after surgery, with specific patterns in left and right TLE. Contralateral language recruitment before surgery is associated with better language outcomes post-surgery in both left and right TLE.
JOURNAL OF NEUROSURGERY
(2021)
Article
Veterinary Sciences
Pau Obregon-Gutierrez, Jaume Bague-Companys, Alex Bach, Virginia Aragon, Florencia Correa-Fiz
Summary: By analyzing the changes in the fecal microbiota of calves, differences related to their health status were found. The microbiota in healthy animals stabilized earlier and showed changes in low abundant bacteria that may play a role in their subsequent health. On the other hand, specific bacteria were found in the fecal microbiota of calves with diarrhea, indicating a higher predisposition to suffer from diarrhea. These findings can contribute to the development of new probiotics for promoting gut health in calves.
VETERINARY SCIENCES
(2022)
Article
Multidisciplinary Sciences
David Andrijevic, Zvonimir Vrselja, Taras Lysyy, Shupei Zhang, Mario Skarica, Ana Spajic, David Dellal, Stephanie L. Thorn, Robert B. Duckrow, Shaojie Ma, Phan Q. Duy, Atagun U. Isiktas, Dan Liang, Mingfeng Li, Suel-Kee Kim, Stefano G. Daniele, Khadija Banu, Sudhir Perincheri, Madhav C. Menon, Anita Huttner, Kevin N. Sheth, Kevin T. Gobeske, Gregory T. Tietjen, Hitten P. Zaveri, Stephen R. Latham, Albert J. Sinusas, Nenad Sestan
Summary: Researchers have developed a technology called OrganEx that can maintain tissue integrity, reduce cell death, and restore molecular and cellular processes in multiple vital organs in a pig's whole body. Single-nucleus transcriptomic analysis revealed gene expression patterns specific to organ and cell type, reflecting specific molecular and cellular repair processes. This study reveals the underappreciated potential for cellular recovery after prolonged whole-body warm ischemia in large mammals.
Article
Infectious Diseases
Manon Prat, Jeremy Guenezan, Bertrand Drugeon, Christophe Burucoa, Olivier Mimoz, Maxime Pichon
Summary: This study aimed to compare the effects of different antiseptic procedures and medical device types on skin bacterial communities. The results showed that antiseptic procedures and PVC types can alter the representation of specific bacteria and are associated with changes in metabolic pathways. This study highlights the importance of optimizing the management of patients with invasive medical devices.
Article
Multidisciplinary Sciences
Lucas P. Henry, Marjolein Bruijning, Simon K. G. Forsberg, Julien F. Ayroles
Summary: The article discusses how the microbiome influences host evolution, proposes that integrating microbiome into quantitative genetics can help unravel the complexity of host-microbiome evolution, and describes the two general ways in which the microbiome may affect host evolutionary potential.
NATURE COMMUNICATIONS
(2021)
Article
Immunology
Changci Zhou, Shuaizheng Gong, Shiting Xiang, Lijuan Liang, Xia Hu, Ruiwen Huang, Zhenyu Liao, Ye Ma, Zhenghui Xiao, Jun Qiu
Summary: The study aimed to understand the alterations in gut microbiota and metabolic pathways in children with focal epilepsy and investigate the changes in these children before and after treatment. The results showed significant differences in gut microbiota and carbohydrate metabolism between children with focal epilepsy and healthy controls. These differences were reduced and carbohydrate metabolism improved after effective treatment.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Review
Immunology
Zain Zaki Zakaria, Shouq Al-Rumaihi, Rana S. Al-Absi, Huda Farah, Muram Elamin, Rahaf Nader, Salma Bouabidi, Sara Elgaili Suleiman, Shahd Nasr, Maha Al-Asmakh
Summary: Recent research has shown that the microbiome plays an important role in human metabolism, immunity, and overall health. The composition of the microbiome is influenced by factors such as environment, diet, weight, and hormones. During pregnancy, significant changes in weight gain and metabolism can lead to alterations in the microbiome. Understanding these microbial changes during pregnancy is crucial for a healthy pregnancy, as they may impact the mother's immune, endocrine, and metabolic status.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Evolutionary Biology
Kay Van Damme, Luca Cornetti, Peter D. Fields, Dieter Ebert, Jason Bond
Summary: The author used phylogenomic approaches to reconstruct the deep-rooted relationships of branchiopod crustaceans. They analyzed a large multigene data set and examined gene tree versus species tree discordance. The study supports the monophyly of the Cladocera and reveals remarkable homoplasy in their body plans. The findings also suggest a Paleozoic origin for the cladoceran ancestor and an ancient rapid radiation at the Perm/Triassic boundary.
SYSTEMATIC BIOLOGY
(2022)
Article
Medicine, General & Internal
Lena Violetta Kraemer, Claudia Mueller-Weinitschke, Tina Zeiss, Harald Baumeister, David Daniel Ebert, Juergen Bengel
Summary: This study aims to evaluate the effectiveness of a theory-based online behavioural activation intervention for people with depression. A randomized controlled trial is conducted to recruit individuals aged 18 to 65 who meet the criteria for a major depressive episode. The primary outcome is depressive symptom severity, and secondary outcomes include behavioural activation, physical activity, and motivational and volitional outcomes. Data will be analyzed on an intention-to-treat basis with additional per-protocol analyses.
Review
Health Care Sciences & Services
Pim Cuijpers, Marketa Ciharova, Soledad Quero, Clara Miguel, Ellen Driessen, Mathias Harrer, Marianna Purgato, David Ebert, Eirini Karyotaki
Summary: Individual participant data (IPD) meta-analyses can provide sufficient statistical power to identify predictors and moderators of psychological treatments for depression. The analysis showed that higher depression severity and older age were associated with better treatment outcomes, while gender, education level, and relationship status were not significant predictors or moderators.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Psychology, Clinical
Severin Hennemann, Katja Boehme, Maria Kleinstaeuber, Harald Baumeister, Ann-Marie Kuechler, David Daniel Ebert, Michael Witthoeft
Summary: This randomized controlled trial tested the efficacy of a guided cognitive-behavioral internet intervention for somatic symptom distress in emerging adults at risk for somatic symptom disorder. The results showed that participants in the intervention group had significantly greater improvements in their symptoms compared to the waitlist control group. The intervention was well-received and satisfaction was high.
JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY
(2022)
Article
Microbiology
Nathalia R. M. de Albuquerque, Karen L. Haag, Peter D. Fields, Andrea Cabalzar, Frida Ben-Ami, Jean-Francois Pombert, Dieter Ebert
Summary: Speciation is a complex and continuous process that poses a challenge in defining species boundaries for organisms with little morphological differentiation. Genomic data can be useful in such cases, as demonstrated by the study on the gut parasite of the cladoceran Daphnia longispina. The researchers characterized its genome and proposed it as a new species within the genus Ordospora.
JOURNAL OF EUKARYOTIC MICROBIOLOGY
(2022)
Article
Health Care Sciences & Services
Esben Skov Jensen, Nicolai Ladegaard, Angelina Isabella Mellentin, David Daniel Ebert, Ingrid Titzler, Ricardo Araya, Arlinda Cerga Pashoja, Jean-Baptiste Haw, Jerome Holtzmann, Roman Cieslak, Ewelina Smoktunowicz, Rosa Banos, Rocio Herrero, Azucena Garcia-Palacios, Cristina Botella, Thomas Berger, Tobias Krieger, Trine Theresa Holmberg, Naira Topooco, Gerhard Andersson, Annemieke van Straten, Lise Kemmeren, Annet Kleiboer, Heleen Riper, Kim Mathiasen
Summary: Sleep disturbance symptoms may have a negative impact on long-term treatment outcomes in bCBT for MDD, but not for conventional treatment.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Health Care Sciences & Services
Joachim Ahlers, Christian Baumgartner, Mareike Augsburger, Andreas Wenger, Doris Malischnig, Nikolaos Boumparis, Thomas Berger, Lars Stark, David D. Ebert, Severin Haug, Michael P. Schaub
Summary: The CANreduce 2.0 intervention can help reduce the frequency and severity of cannabis use, as well as alleviate symptoms, in individuals with attention deficit/hyperactivity disorder. This web-based program has the advantage of increased accessibility and personalized counseling options.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Ecology
Joana L. Santos, Dieter Ebert
Summary: The outcome of parasitic infections is influenced by environmental and host/parasite genetic factors, but geography also plays a role. This study found that high temperatures can affect host-parasite interactions, but the effects vary across different regions.
JOURNAL OF FRESHWATER ECOLOGY
(2022)
Article
Health Care Sciences & Services
Isaac Moshe, Yannik Terhorst, Sarah Paganini, Sandra Schlicker, Laura Pulkki-Raback, Harald Baumeister, Lasse B. Sander, David Daniel Ebert
Summary: This study identified predictors of dropout in a digital intervention for depression in patients with chronic back pain. Factors such as education level, age, and social support were associated with a higher risk of dropout. Combining baseline characteristics and intervention usage data improved the prediction of dropout early in treatment.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Health Care Sciences & Services
Patricia Nixon, David Daniel Ebert, Leif Boss, Peter Angerer, Nico Dragano, Dirk Lehr
Summary: This study found that web-based stress management interventions (SMIs) can effectively reduce stress levels and improve occupational self-efficacy in employees. Occupational self-efficacy played a mediating role, enabling employees to change adverse working conditions. However, person-focused interventions may not be sufficient, and organizational-focused interventions are also needed to comprehensively improve employees' mental health.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Multidisciplinary Sciences
Mingyu Luo, Shaopeng Wang, Serguei Saavedra, Dieter Ebert, Florian Altermatt
Summary: This study developed a spatially explicit metacommunity model to investigate species coexistence in fragmented heterogeneous landscapes. By parameterizing the model with Bayesian approach and analyzing a time-series dataset, the study revealed the interspecific variation in extinction and recolonization processes and their dependencies on habitat size and environmental temperature. This interspecific variation contributes to species coexistence by reducing fitness differences and increasing niche differences.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Environmental Sciences
Lina Braun, Yannik Terhorst, Ingrid Titzler, Johanna Freund, Janika Thielecke, David Daniel Ebert, Harald Baumeister
Summary: Musculoskeletal symptoms are more common in farmers, but the prevalence of chronic pain in this group is unknown. Online interventions based on acceptance and commitment therapy (ACT) may be a promising approach for reducing pain interference in green professions.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Genetics & Heredity
Pascal Angst, Dieter Ebert, Peter D. Fields
Summary: The determinants of genome-wide nucleotide diversity in a species include historical, environmental, and stochastic factors. In the parasite Ordospora colligata, the mode of transmission and interactions with the host surpass the effects of these factors in shaping genomic diversity. Through genomic analysis, we found overlapping phylogeography between O. colligata and its host, indicating a long-term relationship. The observed geographic distribution reflects adaptations to colder habitats and the co-phylogeography allowed calibration of the phylogeny and estimation of mutation rate.
G3-GENES GENOMES GENETICS
(2023)
Article
Genetics & Heredity
Maridel Fredericksen, Peter S. Fields, Louis Du Pasquier, Virginie S. Ricci, Dieter Ebert
Summary: Identifying genes that confer resistance in a coevolving host-parasite system is important for understanding evolution. By comparing resistant and susceptible hosts, analyzing gene expression data, and performing genetic crosses, this study identifies eight candidate genes that may confer resistance to parasites. This research expands our understanding of resistance loci and provides candidates to be tested in future experiments.
Article
Biodiversity Conservation
Vital Heim, Daniel Luescher, Juergen Hottinger, Dieter Ebert
Summary: Researchers proposed a drill attachment for the fast, accurate, and safe deployment of fin-mounted geolocators, successfully tested on several shark species, significantly reducing deployment time and enabling successful tagging even in challenging conditions.
ANIMAL BIOTELEMETRY
(2022)
