Review
Polymer Science
Yiyi Deng, Fabian Mehner, Jens Gaitzsch
Summary: Radical Ring-opening polymerization (RROP) of cyclic ketene acetals (CKAs) is a valuable polymerization technique. This review discusses the progress made in the field, including the synthesis of available CKAs and the understanding of the polymerization mechanism. The potential of producing fully biodegradable polymers through CKAs without vinylenes is highlighted. The control of side reactions, the impact on polymer properties, and the expanded application range of materials from RROP are also explored.
MACROMOLECULAR RAPID COMMUNICATIONS
(2023)
Review
Polymer Science
Jianqun Wang, Youhua Tao
Summary: The review highlights the use of various catalysts, especially metal-based catalysts, for controlled ROP of OCAs. It also summarizes recent progress on the organocatalytic ROP of OCAs and discusses the future development of this method for sustainable polyester synthesis.
MACROMOLECULAR RAPID COMMUNICATIONS
(2021)
Article
Materials Science, Multidisciplinary
Siping Hu, Jianxu Chen, Xun Zhang, Yuying Zhang, Saihu Liao
Summary: Visible light-regulated organocatalytic polymerization has received significant attention in recent years due to its mild, metal-free reaction conditions and the ability to mediate polymerization with spatial and temporal control. In this study, hydroxybenzophenones (BPOHs) were successfully identified as an effective class of photoacid catalysts for the ring-opening polymerization of lactones, resulting in biodegradable polyester products with predictable molecular mass and low dispersity under visible light irradiation.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Polymer Science
Huiqun Wang, Sebla Onbulak, Steven Weigand, Frank S. Bates, Marc A. Hillmyer
Summary: The researchers synthesized a series of polyethylene-graft-aPP graft copolymers and found that increasing aPP content led to decreased melting temperatures and glass transition temperatures of PE, as well as decreased crystallinity. Additionally, the linear viscoelastic behavior of the PE-g-aPP graft copolymers exhibited greatly enhanced dynamic modulus and complex viscosity, with the effect increasing as side chain number and/or length increased.
Article
Chemistry, Multidisciplinary
Maosheng Li, Shuai Zhang, Xiaoyong Zhang, Yanchao Wang, Jinlong Chen, Youhua Tao, Xianhong Wang
Summary: The study describes an effective unimolecular anion-binding organocatalysis for ring-opening polymerization of O-carboxyanhydrides (OCAs), achieving the synthesis of highly isotactic poly(phenyllactic acid) (Ph-PLA) through a dynamic cooperative anion-binding mechanism. This approach addresses the challenge of synthesizing high molecular weight stereoregular polyesters by facilitating efficient chain propagation and maintaining high selectivity for OCA ring-opening over side reactions.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Polymer Science
Hans R. Kricheldorf, Steffen M. Weidner
Summary: The research showed that 2,2'-dihydroxybiphenyl is the most successful cocatalyst for bismuth subsalicylate in ring-opening polymerization of l-lactide, and optimization of reaction time and temperature is crucial for achieving high weight average molecular weights. Additionally, some unusual transesterification reactions were discovered, and triphenylphosphine was found to be an effective catalyst poison.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Polymer Science
Chengliang Wang, Xu Zhang, Wei Zhao, Xin Liu, Qingfu Wang, Jingjiang Sun
Summary: This study introduces a novel organo-catalyzed method for the synthesis of hyperbranched aliphatic polycarbonates (HBPCs). The method allows for precise control over the HBPC structure and the introduction of different functional groups. HBPCs have significant potential for biomedical applications.
Article
Chemistry, Multidisciplinary
Yening Xia, Georg M. Scheutz, Charles P. Easterling, Junpeng Zhao, Brent S. Sumerlin
Summary: This study introduces a method for synthesizing well-defined polyacrylamido-b-polyether block copolymers by combining photoiniferter polymerization and organocatalytic ring-opening polymerization. The compatibility between the two polymerization systems is demonstrated, allowing for the tailored synthesis of block copolymers from chemically distinct monomers.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Jiandong Li, Fusheng Liu, Yalei Liu, Yong Shen, Zhibo Li
Summary: This study presents a method for chemoselective controlled ring-opening polymerization of bio-renewable bifunctional alpha-methylene-delta-valerolactone (MVL) using strong base/urea binary catalysts. The obtained high molecular weight polyester exhibits good mechanical properties. The pristine monomer can be recovered through thermolysis, establishing a closed-loop life cycle.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Fernando Vidal, Sevven Smith, Charlotte K. Williams
Summary: Boron-functionalized polymers have wide applications in opto-electronics, biology, and medicine. However, methods to produce boron-functionalized and degradable polyesters are rare. This study presents a controlled ring-opening copolymerization method to produce boron-functionalized polyesters. The resulting polymers have adjustable structures, molecular weights, and boron functionalities. The boronic ester-functionalized polymers are amorphous and have high glass transition temperatures and good thermal stability. The utility of this method is demonstrated by synthesizing fluorescent spherical nanoparticles. This versatile technology provides a platform for future explorations of degradable and functional polymers.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Materials Science, Multidisciplinary
Martin Castillo-Santillan, Dina Maniar, Maria C. Gutierrez, Priscila Quinonez-Angulo, Jose Roman Torres-Lubian, Katja Loos, Josue D. Mota-Morales
Summary: Designing biocompatible polymeric biomaterials with programmable life cycles is crucial in reducing the negative environmental impact of plastic waste disposal. In this study, deep eutectic solvent monomers (DESm) consisting of l-lactide and various lactones were formulated to obtain polyesters at low temperatures using organocatalysts and solventless conditions. The expansion of DESm allows for the design of polyesters with tailored molecular weights and crystallinity, contributing to programmable degradability. The ROP of DESm under low temperature and solventless conditions holds promise for the sustainable preparation of biodegradable polymers for biomedical applications.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Xun Zhang, Pan Sun, Yu Jiang, Saihu Liao
Summary: In this study, an efficient metal-free organic catalytic system using PADIs as catalysts has been developed for the ring-opening polymerization of ε-caprolactone. The system allows for the synthesis of poly(ε-caprolactone) with predictable molecular weight and narrow dispersity under mild conditions.
CHEMISTRY-AN ASIAN JOURNAL
(2023)
Article
Materials Science, Textiles
Petr Mikes, Jana Horakova, Ales Saman, Lucie Vejsadova, Paul Topham, Winita Punyodom, Manita Dumklang, Vera Jencova
Summary: The study compared the electrospinning of various polylactide and polycaprolactone copolymers and homopolymers. The results showed that the electrospinnability of polymeric solutions depends on molecular weight and the PLA/PCL ratio in the final copolymer. Degradation rates were influenced by molecular weight, polymer crystallinity, and enzyme specificity, with differences in degradation impact between lipase and Proteinase K observed. Electrospun PLLA materials were found to support fibroblast adhesion and proliferation, and all tested materials were cytocompatible with 3T3 mouse fibroblasts.
JOURNAL OF INDUSTRIAL TEXTILES
(2021)
Article
Polymer Science
Sebla Onbulak, Marc A. Hillmyer
Summary: The synthesis of sequence-controlled poly(ethylene-co-styrene) copolymers is challenging due to limitations in catalytic olefin polymerizations. An alternative method using ROMP of cyclic olefins followed by hydrogenation can generate ethylene copolymers with regioregularity. Investigating the ROMP of low-strain cyclododecenes provided useful information for mechanistic aspects of polymerization.
Article
Polymer Science
Ilya Nifant'ev, Andrey Shlyakhtin, Vladimir Bagrov, Evgeny Shaputkin, Alexander Tavtorkin, Pavel Ivchenko
Summary: The study found that the acyl chlorides derived from NHS and MI can efficiently terminate the living ring-opening polymerization of aliphatic polyesters, producing NHS- and MI-functionalized polymers with high yields. These polymers exhibit high reactivity towards amine- and thiol-containing model substrates in both organic and aqueous media.
Article
Chemistry, Inorganic & Nuclear
Melek Tercan, Elif Karacan Yeldir, Osman Dayan, Ayhan Oral
INORGANIC AND NANO-METAL CHEMISTRY
(2020)
Article
Biochemistry & Molecular Biology
S. J. Hepziba Magie Jessima, S. Subhashini, Avni Berisha, Ayhan Oral, Subramanian Sathy Srikandan
Summary: The study investigated the corrosion inhibition of mild steel in 1 M HCl using Disodium EDTA functionalized chitosan, which exhibited an inhibition efficiency of 96.63% at 303 K. Experimental and theoretical results supported an adsorption process of initial physisorption followed by chemisorption. Statistical analysis using Two-way Analysis of Variance and software modeling showed a quartic model with the highest R2 value of 0.973.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Polymer Science
Fatih Bayrak, Emriye Ay, Ayhan Oral, Tamer Karayildirim, Kadir Ay
Summary: Ten new carbohydrate-based aromatic polyurethanes were synthesized using isomannide and/or a new 1,2,3-triazole isomannide derivative as the diol source, with different isocyanate sources. The structural elucidation was performed using spectroscopic techniques and thermal behavior analysis was done. Results showed that the diisocyanate source had more impact on the surface properties of polymers, leading to different morphologies in the synthesized polymers.
IRANIAN POLYMER JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Elif Karacan Yeldir, Ayhan Oral
Summary: The study prepared chitosan microcapsules and cinnamaldehyde encapsulated microspheres using a green method. The release study showed that chitosan microspheres could sustainably release cinnamaldehyde, indicating their potential as a sustained release system.
MACEDONIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING
(2021)
Article
Pharmacology & Pharmacy
Salih Can Suner, Yeliz Yildirim, Fatma Yurt, Derya Ozel, Ayhan Oral, Ismail Ozturk
Summary: This study compared the release kinetics of three different antibiotics loaded on nanofibers in solution and their thermal properties, finding differences in thermal degradation and glass transition temperatures among the antibiotics. As drug loading amount increased, drug release amount gradually increased, while formulations containing different antibiotics showed inhibitory effects on Staphylococcus aureus and Escherichia coli.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Microbiology
Seyhan Ulusoy, Ramadan B Akalin, Halime cevikbas, Avni Berisha, Ayhan Oral, Gulgun Bosgelmez-Tinaz
Summary: The study shows that zeolites can disrupt the QS systems of Chromobacterium violaceum and Pseudomonas aeruginosa by adsorbing AHL signal molecules, reducing their production and virulence. This finding may provide new insights for the treatment of P. aeruginosa-related infections.
FUTURE MICROBIOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Merve Danisman, Avni Berisha, Omar Dagdag, Ayhan Oral
Summary: Surface modification of particles using enzymes instead of chemicals can avoid limitations and energy loss, and is widely applied in various fields.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Polymer Science
Cengiz Caner, Fatih Rahvali, Muhammed Yuceer, Ayhan Oral
Summary: This research investigated the effects of different types and concentrations of Cloisite on the properties of chitosan films. Cloisite significantly decreased the lightness (L*) depending on the type and concentration. Films containing Cloisite showed improved oxygen barrier properties by 34.5%-73.6% and water barrier properties by up to 84.61%. The dispersed Cloisite clays enhanced the thermal stability, barrier properties, and tensile properties of chitosan.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2023)
Article
Chemistry, Multidisciplinary
Gurkan Alkan, Seyhan Ulusoy, Mert Akgun, Ayhan Oral
Summary: In recent years, nanofibers loaded with pharmaceutical agents have become increasingly important in various medical applications due to their advantages. This study successfully loaded polylactic acid (PLA)-gelatin (Gel) nanofibers with Ibuprofen-Na/Paracetamol. The nanofibers were characterized and their antibacterial and antibiofilm activities were evaluated. The results showed that the nanofibers exhibited antibacterial activity and were promising materials for wound healing applications.
MACEDONIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING
(2023)
Article
Polymer Science
Tuba Gungor Ertugral, Merve Danisman, Ayhan Oral
Summary: Cold storage is a healthy method of preserving food, but it often relies on expensive and non-environmentally friendly fossil fuel-based materials. This study explores the use of microcapsules with heat storage and diffusion properties in packaging materials to minimize the use of fossil fuels. The results show that these microcapsules can effectively maintain the desired storage temperature range for sensitive food products.
POLYMER-PLASTICS TECHNOLOGY AND MATERIALS
(2023)
Article
Marine & Freshwater Biology
Sezginer Tuncer, Nazik Oegretmen, Fikret Cakir, Alkan Oztekin, Ayhan Oral, Salih Can Suner
Summary: This study investigates the bloom of the straight-needle pteropod Creseis acicula in the surface waters of the canakkale Strait, Turkey, and discusses its relationship with environmental changes, attributing its proliferation to elevated pH levels and temperature caused by anthropogenic activities rather than global atmospheric CO2 levels.
OCEANOLOGICAL AND HYDROBIOLOGICAL STUDIES
(2021)
Article
Chemistry, Multidisciplinary
Hayfa Argui, Salih Can Suner, Cagdas Deniz Periz, Seyhan Ulusoy, Gulen Turker, Mossadok Ben-Attia, Fikret Buyukkaya, Ayhan Oral, Yalcin Coskun, Hechmi Said
Summary: This study successfully prepared poly (lactic acid) nanofibers containing cypress essential oil using electrospinning technology. The thermal stability of the nanofibers decreased with the increase of cypress essential oil content, while the flexibility increased. The nanofibers showed antibacterial activity against Escherichia coli and Staphylococcus aureus, with inhibition zone diameters larger than those in the presence of Kanamycin.
Article
Chemistry, Multidisciplinary
Fatih Bayrak, Ayhan Oral, Kadir Ay
Summary: New polyurethanes were synthesized by reacting newly synthesized compounds with existing materials, and their thermal properties and molecular structures were investigated through experiments.
MACEDONIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING
(2021)
Article
Plant Sciences
Hayfa Argui, Oumayma Ben Youchret-Zalleza, Salih Can Suner, Cagdas Deniz Periz, Gulen Turker, Seyhan Ulusoy, Mossadok Ben-Attia, Fikret Buyukkaya, Ayhan Oral, Yalcin Coskun, Hechmi Said
Summary: The Cupressus sempervirens L. essential oil exhibited significant antioxidant and antibacterial activities, particularly against Staphylococcus aureus, Enterococcus faecalis, and Escherichia coli. It also showed contact toxic effect and repellent activity against Sitophilus granarius adults.
JOURNAL OF ESSENTIAL OIL BEARING PLANTS
(2021)
Article
Chemistry, Multidisciplinary
Arianit A. Reka, Blagoj Pavlovski, Emira Fazlija, Avni Berisha, Musaj Pacarizi, Maria Daghmehchi, Carmen Sacalis, Gligor Jovanovski, Petre Makreski, Ayhan Oral
Summary: The diatomaceous earth (DE) from North Macedonia's Mariovo region was characterized and thermally modified, revealing significant changes at high temperatures and improving the understanding of silica phase transition mechanisms and relevant phase alterations.
Article
Materials Science, Biomaterials
Christopher Igwe Idumah, I. C. Nwuzor, S. R. Odera, U. J. Timothy, U. Ngenegbo, F. A. Tanjung
Summary: This paper presents recent advancements in drug delivery applications of polymeric hydrogel nanoarchitectures and hydrogel derivatives, including the incorporation of nanoparticulates and the enhancement of the chemical, biological, electrical, and mechanical properties of hydrogels. The application of magnetically responsive and smart hydrogels as drug delivery systems is also discussed.
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2024)
Article
Materials Science, Biomaterials
Remya K. Rajan, Sunitha Chandran, Annie John, Ramesh Parameswaran
Summary: This study outlines the fabrication and characterization of pamidronate (PDS) embedded nanofibrous scaffolds based on polycaprolactone/polycaprolactone-polyethyleneglycol-polycaprolactone (PCL/CEC) blends for osteoporotic bone defect management. The electrospinning technique was utilized to fabricate PDS-loaded scaffolds, and the effect of PDS on the blends was evaluated in terms of surface morphology, wettability, biodegradability, and in vitro cytocompatibility. The results showed that the PCL/CEC-PDS scaffolds had a fibroporous architecture, appropriate mechanical properties, and the ability to support cell growth, indicating their potential for managing osteoporotic bone defects.
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2024)
Article
Materials Science, Biomaterials
Kubra Aydin, Handan Sevim, Hatice Kaplan Can
Summary: This study aims to develop a new dental material by designing, synthesizing, and characterizing nanocomposites, and evaluate their cytotoxic effects on human gingival fibroblasts. The results of this research will contribute to a better understanding of the properties and safety of this material, providing reference for clinical applications in dentistry.
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2024)
Review
Materials Science, Biomaterials
Angelica Jimenez-Rosales, Stefani Cortes-Camargo, Pedro Estanislao Acuna-Avila
Summary: The immune response to drug-delivering systems and implanted medical devices based on biomaterials is complex, and the goal is to design biomaterials that can respond to stimuli, preserve tissue function, and optimize cellular structures. Understanding the material's structure and location, as well as the severity of damage and other factors, is crucial in developing biocompatible biomaterials.
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2024)
Article
Materials Science, Biomaterials
Fatemeh Daliri Shadmehri, Ehsan Karimi, Ehsan Saburi
Summary: Bone tissue engineering utilizes polymeric scaffolds and stem cells to create a supportive matrix resembling the in vivo environment for bone repair. The study found that a composite matrix of polycaprolactone and fibrin enhanced the differentiation of adipose-derived stem cells into osteo-like cells.
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2024)
