7-Ketocholesterol-induced lysosomal dysfunction exacerbates vascular smooth muscle cell calcification via oxidative stress

Atorvastatin Protects Vascular Smooth Muscle Cells From TGF-�1-Stimulated Calcification by Inducing Autophagy via Suppression of the �-Catenin Pathway

(2014) Demin Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

5-aza-2´-Deoxycytidine, a DNA Methyltransferase Inhibitor, Facilitates the Inorganic Phosphorus-Induced Mineralization of Vascular Smooth Muscle Cells

(2014) Takuya Azechi et al.   Journal of Atherosclerosis and Thrombosis

7-Ketocholesterol Induces Autophagy in Vascular Smooth Muscle Cells through Nox4 and Atg4B

(2013) Chaoyong He et al.   AMERICAN JOURNAL OF PATHOLOGY

ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons

(2013) Hideaki Matsui et al.   FEBS LETTERS

Phosphate-induced autophagy counteracts vascular calcification by reducing matrix vesicle release

(2013) Xiao-Yan Dai et al.   KIDNEY INTERNATIONAL

Ceramide Mediates Ox-LDL-Induced Human Vascular Smooth Muscle Cell Calcification via p38 Mitogen-Activated Protein Kinase Signaling

(2013) Lizhen Liao et al.   PLoS One

Lysosome Dysfunction Enhances Oxidative Stress-Induced Apoptosis through Ubiquitinated Protein Accumulation in Hela Cells

(2012) Chunyan Yu et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Lipid accumulation and lysosomal pathways contribute to dysfunction and apoptosis of human endothelial cells caused by 7-oxysterols

(2011) Wei Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Arterial Calcification in Chronic Kidney Disease: Key Roles for Calcium and Phosphate

(2011) Catherine M. Shanahan et al.   CIRCULATION RESEARCH

7-Ketocholesterol, a Major Oxysterol, Promotes Pi-Induced Vascular Calcification in Cultured Smooth Muscle Cells

(2011) Eiji Saito et al.   Journal of Atherosclerosis and Thrombosis

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders

(2010) Alessandro Fraldi et al.   EMBO JOURNAL

Autophagy in Atherosclerosis

(2009) Wim Martinet et al.   CIRCULATION RESEARCH

Mechanism of phosphate-induced calcification in rat aortic tissue culture: possible involvement of Pit-1 and apoptosis

(2009) Sachiko Mune et al.   Clinical and Experimental Nephrology

Oxidative Stress Induces Vascular Calcification through Modulation of the Osteogenic Transcription Factor Runx2 by AKT Signaling

(2008) Chang Hyun Byon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE