Probing the Effect of Physiological Concentrations of IL-6 on Insulin Secretion by INS-1 832/3 Insulinoma Cells under Diabetic-Like Conditions

Do skeletal muscle-secreted factors influence the function of pancreatic β-cells?

(2018) Jonathan P. Barlow et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Exercise training protects human and rodent β cells against endoplasmic reticulum stress and apoptosis

(2018) Flavia M. M. Paula et al.   FASEB JOURNAL

The impairment of glucose-stimulated insulin secretion in pancreatic β-cells caused by prolonged glucotoxicity and lipotoxicity is associated with elevated adaptive antioxidant response

(2017) Jingqi Fu et al.   FOOD AND CHEMICAL TOXICOLOGY

IL-1β reciprocally regulates chemokine and insulin secretion in pancreatic β-cells via NF-κB

(2015) Susan J. Burke et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Exercise increases pancreatic β-cell viability in a model of type 1 diabetes through IL-6 signaling

(2015) Flavia M. M. Paula et al.   FASEB JOURNAL

Skeletal Muscle to Pancreatic β-Cell Cross-talk: The Effect of Humoral Mediators Liberated by Muscle Contraction and Acute Exercise on β-Cell Apoptosis

(2015) Camilla S. Christensen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Uncoupling protein-2 attenuates palmitoleate protection against the cytotoxic production of mitochondrial reactive oxygen species in INS-1E insulinoma cells

(2015) Jonathan Barlow et al.   Redox Biology

Novel insights into pancreatic β-cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells

(2013) Jonathan Barlow et al.   BIOCHEMICAL JOURNAL

Circulating Levels of IL-1B+IL-6 Cause ER Stress and Dysfunction in Islets From Prediabetic Male Mice

(2013) Christina M. O'Neill et al.   ENDOCRINOLOGY

Identification and Validation of Novel Contraction-Regulated Myokines Released from Primary Human Skeletal Muscle Cells

(2013) Silja Raschke et al.   PLoS One

IL-6 Trans-Signaling via the Soluble IL-6 Receptor: Importance for the Pro-Inflammatory Activities of IL-6

(2012) Stefan Rose-John   International Journal of Biological Sciences

Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets

(2012) Mauricio da Silva Krause et al.   JOURNAL OF ENDOCRINOLOGY

Interleukin-6 Enhances Glucose-Stimulated Insulin Secretion From Pancreatic  -Cells: Potential Involvement of the PLC-IP3-Dependent Pathway

(2011) T. Suzuki et al.   DIABETES

Bimodal Effect on Pancreatic  -Cells of Secretory Products From Normal or Insulin-Resistant Human Skeletal Muscle

(2011) K. Bouzakri et al.   DIABETES

Interleukin-6 treatment induces beta-cell apoptosis via STAT-3-mediated nitric oxide production

(2011) Yoon Sin Oh et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells

(2011) Helga Ellingsgaard et al.   NATURE MEDICINE

Pancreatic β-Cell Death in Response to Pro-Inflammatory Cytokines Is Distinct from Genuine Apoptosis

(2011) J. Jason Collier et al.   PLoS One

Improved Pancreatic  -Cell Function in Type 2 Diabetic Patients After Lifestyle-Induced Weight Loss Is Related to Glucose-Dependent Insulinotropic Polypeptide

(2010) T. P. J. Solomon et al.   DIABETES CARE

Exercise and Type 2 Diabetes: The American College of Sports Medicine and the American Diabetes Association: joint position statement

(2010) S. R. Colberg et al.   DIABETES CARE

Cytokines in the Progression of Pancreaticβ-Cell Dysfunction

(2010) Chunjiong Wang et al.   International Journal of Endocrinology

Cellular Production of n-3 PUFAs and Reduction of n-6-to-n-3 Ratios in the Pancreatic  -Cells and Islets Enhance Insulin Secretion and Confer Protection Against Cytokine-Induced Cell Death

(2009) D. Wei et al.   DIABETES

Islet Inflammation in Type 2 Diabetes: From metabolic stress to therapy

(2008) M. Y. Donath et al.   DIABETES CARE