Whole-exome sequencing defines the mutational landscape of pheochromocytoma and identifiesKMT2Das a recurrently mutated gene

KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation

(2015) Changcun Guo et al.   Oncotarget

UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells

(2014) Jae-Hwan Kim et al.   CANCER RESEARCH

Testing for germline mutations in sporadic pheochromocytoma/paraganglioma: a systematic review

(2014) Juan P. Brito et al.   CLINICAL ENDOCRINOLOGY

Frequent EPAS1/HIF2α exons 9 and 12 mutations in non-familial pheochromocytoma

(2014) Jenny Welander et al.   ENDOCRINE-RELATED CANCER

Rare Germline Mutations Identified by Targeted Next-Generation Sequencing of Susceptibility Genes in Pheochromocytoma and Paraganglioma

(2014) Jenny Welander et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Next-generation sequencing reveals frequent consistent genomic alterations in small cell undifferentiated lung cancer

(2014) J S Ross et al.   JOURNAL OF CLINICAL PATHOLOGY

Identification of genomic alterations in oesophageal squamous cell cancer

(2014) Yongmei Song et al.   NATURE

Genomic and molecular characterization of esophageal squamous cell carcinoma

(2014) De-Chen Lin et al.   NATURE GENETICS

Paraganglioma and phaeochromocytoma: from genetics to personalized medicine

(2014) Judith Favier et al.   Nature Reviews Endocrinology

Tumoral EPAS1 (HIF2A) mutations explain sporadic pheochromocytoma and paraganglioma in the absence of erythrocytosis

(2013) Iñaki Comino-Méndez et al.   HUMAN MOLECULAR GENETICS

Germline mutations in FH confer predisposition to malignant pheochromocytomas and paragangliomas

(2013) Luis Jaime Castro-Vega et al.   HUMAN MOLECULAR GENETICS

Somatic Mutations inH-RASin Sporadic Pheochromocytoma and Paraganglioma Identified by Exome Sequencing

(2013) Joakim Crona et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma

(2013) Jessica Okosun et al.   NATURE GENETICS

Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy

(2013) Cristina Balbás-Martínez et al.   NATURE GENETICS

Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma

(2012) Adrian M. Dubuc et al.   ACTA NEUROPATHOLOGICA

Integrative genomics reveals frequent somatic NF1 mutations in sporadic pheochromocytomas

(2012) Jenny Welander et al.   HUMAN MOLECULAR GENETICS

Somatic NF1 inactivation is a frequent event in sporadic pheochromocytoma

(2012) Nelly Burnichon et al.   HUMAN MOLECULAR GENETICS

SomaticHIF2AGain-of-Function Mutations in Paraganglioma with Polycythemia

(2012) Zhengping Zhuang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetics and clinical characteristics of hereditary pheochromocytomas and paragangliomas

(2011) Jenny Welander et al.   ENDOCRINE-RELATED CANCER

A mutation screen in patients with Kabuki syndrome

(2011) Yun Li et al.   HUMAN GENETICS

Candidate driver genes in microsatellite-unstable colorectal cancer

(2011) Pia Alhopuro et al.   INTERNATIONAL JOURNAL OF CANCER

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

(2011) Ryan D. Morin et al.   NATURE

Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma

(2011) Iñaki Comino-Méndez et al.   NATURE GENETICS

Epigenetic regulator MLL2 shows altered expression in cancer cell lines and tumors from human breast and colon

(2010) Thanemozhi G Natarajan et al.   Cancer Cell International

MLL2 mutation spectrum in 45 patients with Kabuki syndrome

(2010) Aimée D. C. Paulussen et al.   HUMAN MUTATION

Germline mutations in TMEM127 confer susceptibility to pheochromocytoma

(2010) Yuejuan Qin et al.   NATURE GENETICS

Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome

(2010) Sarah B Ng et al.   NATURE GENETICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

The Genetic Landscape of the Childhood Cancer Medulloblastoma

(2010) D. W. Parsons et al.   SCIENCE

Cancer-Specific High-Throughput Annotation of Somatic Mutations: Computational Prediction of Driver Missense Mutations

(2009) H. Carter et al.   CANCER RESEARCH

Frequent mutations in the MITF pathway in melanoma

(2009) Julia C. Cronin et al.   Pigment Cell & Melanoma Research

The kinesin KIF1B  acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor

(2008) S. Schlisio et al.   GENES & DEVELOPMENT

P18is a tumor suppressor gene involved in human medullary thyroid carcinoma and pheochromocytoma development

(2008) Wendy van Veelen et al.   INTERNATIONAL JOURNAL OF CANCER

PHD2Mutation and Congenital Erythrocytosis with Paraganglioma

(2008) Charline Ladroue et al.   NEW ENGLAND JOURNAL OF MEDICINE