Possible Molecular Targets of Novel Ruthenium Complexes in Antiplatelet Therapy

Structure-Antiplatelet Activity Relationships of Novel Ruthenium (II) Complexes: Investigation of Its Molecular Targets

(2018) Chih-Hsuan Hsia et al.   MOLECULES

Ruthenium complex exerts antineoplastic effects that are mediated by oxidative stress without inducing toxicity in Walker-256 tumor-bearing rats

(2017) Carlos Eduardo Alves de Souza et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antiplatelet Activity of a Newly Synthesized Novel Ruthenium (II): A Potential Role for Akt/JNK Signaling

(2017) Themmila Khamrang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cytotoxicity in vitro, cellular uptake, localization and apoptotic mechanism studies induced by ruthenium(II) complex

(2017) Jincan Chen et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

The Personalization of Clopidogrel Antiplatelet Therapy: The Role of Integrative Pharmacogenetics and Pharmacometabolomics

(2017) Arwa M. Amin et al.   Cardiology Research and Practice

A novel ruthenium (II)-derived organometallic compound, TQ-6, potently inhibits platelet aggregation: Ex vivo and in vivo studies

(2017) Chih-Hsuan Hsia et al.   Scientific Reports

Ruthenium-conjugated chrysin analogues modulate platelet activity, thrombus formation and haemostasis with enhanced efficacy

(2017) Divyashree Ravishankar et al.   Scientific Reports

Genetic risk factors for venous thrombosis in women using combined oral contraceptives: update of the PILGRIM study

(2016) P. Suchon et al.   CLINICAL GENETICS

Mitochondria-targeted ruthenium (II) polypyridyl complexes with benzofuran group for live cell imaging

(2016) Li Xu et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

A ruthenium(II) complex inhibits tumor growth in vivo with fewer side-effects compared with cisplatin

(2015) Jin-Quan Wang et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Anticancer activity studies of a ruthenium(II) polypyridyl complex against human hepatocellular (BEL-7402) cells

(2015) Wei Li et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Multinuclear ruthenium(ii) complexes as anticancer agents

(2014) Anil K. Gorle et al.   NEW JOURNAL OF CHEMISTRY

Cytotoxicity Studies of Cyclometallated Ruthenium(II) Compounds: New Applications for Ruthenium Dyes

(2014) Bruno Peña et al.   ORGANOMETALLICS

The path for metal complexes to a DNA target

(2013) Alexis C. Komor et al.   CHEMICAL COMMUNICATIONS

Tyrosine Phosphorylation on Spleen Tyrosine Kinase (Syk) Is Differentially Regulated in Human and Murine Platelets by Protein Kinase C Isoforms

(2013) Lorena Buitrago et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria are the primary target in the induction of apoptosis by chiral ruthenium(II) polypyridyl complexes in cancer cells

(2013) Jin-Quan Wang et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Studies of ruthenium(ii)-2,2′-bisimidazole complexes on binding to G-quadruplex DNA and inducing apoptosis in HeLa cells

(2013) Yu Xia et al.   NEW JOURNAL OF CHEMISTRY

Highly cytotoxic diruthenium trithiolato complexes of the type [(η6-p-MeC6H4Pri)2Ru2(μ2-SR)3]+: synthesis, characterization, molecular structure and in vitro anticancer activity

(2013) Federico Giannini et al.   NEW JOURNAL OF CHEMISTRY

Differentiation of cGMP-dependent and -independent nitric oxide effects on platelet apoptosis and reactive oxygen species production using platelets lacking soluble guanylyl cyclase

(2011) Natalia Rukoyatkina et al.   THROMBOSIS AND HAEMOSTASIS

A novel histidine tyrosine phosphatase, TULA-2, associates with Syk and negatively regulates GPVI signaling in platelets

(2010) D. H. Thomas et al.   BLOOD

Cilostazol for prevention of secondary stroke (CSPS 2): an aspirin-controlled, double-blind, randomised non-inferiority trial

(2010) Yukito Shinohara et al.   LANCET NEUROLOGY

Role of Platelets in Atherothrombosis

(2009) Lisa K. Jennings   AMERICAN JOURNAL OF CARDIOLOGY

Inhibition of metastasis in a murine 4T1 breast cancer model by liposomes preventing tumor cell-platelet interactions

(2009) Jane Wenzel et al.   CLINICAL & EXPERIMENTAL METASTASIS

Human platelet pathology related to defects in the G-protein signaling cascade

(2009) C. VAN GEET et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Recent developments in ruthenium anticancer drugs

(2009) Aviva Levina et al.   Metallomics

Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway

(2008) H. Yin et al.   BLOOD

Analysis of Fyn function in hemostasis and  IIb 3-integrin signaling

(2008) K. B. Reddy et al.   JOURNAL OF CELL SCIENCE

Mechanisms of Thrombus Formation

(2008) Bruce Furie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of bortezomib on platelet aggregation and ATP release in human platelets, in vitro

(2007) Ferit Avcu et al.   THROMBOSIS RESEARCH