Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 2, Pages -Publisher
MDPI
DOI: 10.3390/ijms19020405
Keywords
microRNA; myogenesis; muscle atrophy; exercise; sport injury
Funding
- National Natural Science Foundation of China [31571228]
- Research Project Foundation from General Administration of Sport of China [2014B093]
- Hubei Superior Discipline Groups of Physical Education and Health Promotion
- Outstanding Youth Scientific and Technological Innovation Team from Hubei Provincial Department of Education [T201624]
- Chutian Scholar Program
- Innovative Project Foundation for Graduate Student from Wuhan Sports University [201701]
- Innovative Start-up Foundation from Wuhan Sports University
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Skeletal muscle comprising approximately 40% of body weight is highly important for locomotion and metabolic homeostasis. The growth and regeneration of skeletal muscle are highly organized processes; thus, it is not surprising to reveal certain complexity during these regulatory processes. Recently, a large number of evidence indicate that microRNAs can result in obvious impacts on growth, regeneration and metabolism of skeletal muscle. In this review, recent research achievements of microRNAs in regulating myogenesis, atrophy and aging during exercise intervention are discussed, which will provide the guidance for developing potential applications of microRNAs in health promotion and rehabilitation of sports injuries.
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