VEGF Signaling in Neurological Disorders

ErbB4 protects against neuronal apoptosis via activation of YAP/PIK3CB signaling pathway in a rat model of subarachnoid hemorrhage

(2017) Feng Yan et al.   EXPERIMENTAL NEUROLOGY

Cardiovascular Autonomic Dysfunction in Patients with Drug-Induced Parkinsonism

(2017) Joong-Seok Kim et al.   Journal of Clinical Neurology

Post–spinal cord injury astrocyte-mediated functional recovery in rats after intraspinal injection of the recombinant adenoviral vectors Ad5-VEGF and Ad5-ANG

(2017) Tatyana Povysheva et al.   JOURNAL OF NEUROSURGERY-SPINE

Global, regional, and national age-sex specific mortality for 264 causes of death, 1980–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2017) Mohsen Naghavi et al.   LANCET

Efficacy and safety of bevacizumab treatment for refractory brain edema

(2017) Xiangying Meng et al.   MEDICINE

Vascular Endothelial Growth Factor Isoform-B Stimulates Neurovascular Repair After Ischemic Stroke by Promoting the Function of Pericytes via Vascular Endothelial Growth Factor Receptor-1

(2017) Noëmie Jean LeBlanc et al.   MOLECULAR NEUROBIOLOGY

Vagotomy and Parkinson disease

(2017) Bojing Liu et al.   NEUROLOGY

Phase I Trial of Radiosurgery Dose Escalation Plus Bevacizumab in Patients With Recurrent/Progressive Glioblastoma

(2017) Mahmoud Abbassy et al.   NEUROSURGERY

Glial Cell Line-Derived Neurotrophic Factor Gene Delivery in Parkinson's Disease: A Delicate Balance between Neuroprotection, Trophic Effects, and Unwanted Compensatory Mechanisms

(2017) Liliane Tenenbaum et al.   Frontiers in Neuroanatomy

Development of acute hydrocephalus does not change brain tissue mechanical properties in adult rats, but in juvenile rats

(2017) Alice C. Pong et al.   PLoS One

Prospective comparison among transient elastography, supersonic shear imaging, and ARFI imaging for predicting fibrosis in nonalcoholic fatty liver disease

(2017) Myoung Seok Lee et al.   PLoS One

The function of orthologues of the human Parkinson's disease gene LRRK2 across species: implications for disease modelling in preclinical research

(2016) R. G. Langston et al.   BIOCHEMICAL JOURNAL

Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease

(2016) Amy R. Nelson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Metastatic Colorectal Cancer: A Systematic Review of the Value of Current Therapies

(2016) Daniel A. Goldstein et al.   Clinical Colorectal Cancer

Deferoxamine-mediated up-regulation of HIF-1α prevents dopaminergic neuronal death via the activation of MAPK family proteins in MPTP-treated mice

(2016) Chuang Guo et al.   EXPERIMENTAL NEUROLOGY

Vascular Smooth Muscle Sirtuin-1 Protects Against Diet-Induced Aortic StiffnessNovelty and Significance

(2016) Jessica L. Fry et al.   HYPERTENSION

Exercise-induced changes of cerebrospinal fluid vascular endothelial growth factor in adult chronic hydrocephalus patients

(2016) Jun Yang et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Global, regional, and national levels of maternal mortality, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2016) Nicholas J Kassebaum et al.   LANCET

Vascular endothelial growth factor: a neurovascular target in neurological diseases

(2016) Christian Lange et al.   Nature Reviews Neurology

Ibuprofen or piroxicam protects nigral neurons and delays the development of l -dopa induced dyskinesia in rats with experimental Parkinsonism: Influence on angiogenesis

(2016) Asmaa M. Teema et al.   NEUROPHARMACOLOGY

Matrix stiffening promotes a tumor vasculature phenotype

(2016) Francois Bordeleau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus

(2016) Joon W. Shim et al.   Scientific Reports

Neuroprotective Effect of VEGF-Mimetic Peptide QK in Experimental Brain Ischemia Induced in Rat by Middle Cerebral Artery Occlusion

(2015) Giuseppe Pignataro et al.   ACS Chemical Neuroscience

Aqueductal Stroke Volume: Comparisons with Intracranial Pressure Scores in Idiopathic Normal Pressure Hydrocephalus

(2015) G. Ringstad et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Pathophysiology of Hypoperfusion of the Precuneus in Early Alzheimer's Disease

(2015) J. Scott Miners et al.   BRAIN PATHOLOGY

Enhanced Hippocampal Neurogenesis in APP/Ps1 Mouse Model of Alzheimer’s Disease After Implantation of VEGF-loaded PLGA Nanospheres

(2015) E. Herran et al.   Current Alzheimer Research

Delayed Inhibition of VEGF Signaling after Stroke Attenuates Blood-Brain Barrier Breakdown and Improves Functional Recovery in a Comorbidity-Dependent Manner

(2015) P. Reeson et al.   JOURNAL OF NEUROSCIENCE

Disease-modifying strategies for Parkinson's disease

(2015) Lorraine V. Kalia et al.   MOVEMENT DISORDERS

Increased CSF biomarkers of angiogenesis in Parkinson disease

(2015) Shorena Janelidze et al.   NEUROLOGY

Alterations of the blood-spinal cord barrier in sporadic amyotrophic lateral sclerosis

(2015) Shoichi Sasaki   NEUROPATHOLOGY

Stimulation of endothelin B receptors by IRL-1620 decreases the progression of Alzheimer’s disease

(2015) S. Briyal et al.   NEUROSCIENCE

Neuregulin 1 protects against ischemic brain injury via ErbB4 receptors by increasing GABAergic transmission

(2015) Y.-F. Guan et al.   NEUROSCIENCE

“Smooth Muscle Cell Stiffness Syndrome”—Revisiting the Structural Basis of Arterial Stiffness

(2015) Nancy L. Sehgel et al.   Frontiers in Physiology

Aging impairs smooth muscle-mediated regulation of aortic stiffness: a defect in shock absorption function?

(2014) Yuan Z. Gao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

VEGF: A potential target for hydrocephalus

(2014) Joon W. Shim et al.   CELL AND TISSUE RESEARCH

Deletion of Placental Growth Factor Prevents Diabetic Retinopathy and Is Associated With Akt Activation and HIF1α-VEGF Pathway Inhibition

(2014) Hu Huang et al.   DIABETES

Parkinson's Disease and the Cardio-ankle Vascular Stiffness Index

(2014) Jun Suzuki et al.   INTERNAL MEDICINE

Parkinson disease and smoking revisited: Ease of quitting is an early sign of the disease

(2014) B. Ritz et al.   NEUROLOGY

Haemodynamic and extracellular matrix cues regulate the mechanical phenotype and stiffness of aortic endothelial cells

(2014) Caitlin Collins et al.   Nature Communications

RNA in blood is altered prior to hemorrhagic transformation in ischemic stroke

(2013) Glen C. Jickling et al.   ANNALS OF NEUROLOGY

Comparison of vascular growth factors in the murine brain reveals placenta growth factor as prime candidate for CNS revascularization

(2013) E. I. Gaal et al.   BLOOD

Clinical significance of plasma VEGF value in ischemic stroke - research for biomarkers in ischemic stroke (REBIOS) study

(2013) Ryu Matsuo et al.   BMC Neurology

Vascular endothelial growth factor in the CSF of elderly patients with ventriculomegaly: Variability, periodicity and levels in drainage responders and non-responders

(2013) Jun Yang et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Heart-type fatty acid binding protein and vascular endothelial growth factor: cerebrospinal fluid biomarker candidates for Alzheimer’s disease

(2013) Liang-Hao Guo et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

VEGF, which is elevated in the CSF of patients with hydrocephalus, causes ventriculomegaly and ependymal changes in rats

(2013) Joon W. Shim et al.   EXPERIMENTAL NEUROLOGY

VEGF-releasing biodegradable nanospheres administered by craniotomy: A novel therapeutic approach in the APP/Ps1 mouse model of Alzheimer's disease

(2013) Enara Herrán et al.   JOURNAL OF CONTROLLED RELEASE

Comparative study of the neurotrophic effects elicited by VEGF-B and GDNF in preclinical in vivo models of Parkinson’s disease

(2013) X. Yue et al.   NEUROSCIENCE

Decreased serum levels of the angiogenic factors VEGF and TGF-β1 in Alzheimer's disease and amnestic mild cognitive impairment

(2013) Li Huang et al.   NEUROSCIENCE LETTERS

VEGF significantly restores impaired memory behavior in Alzheimer's mice by improvement of vascular survival

(2013) Piotr Religa et al.   Scientific Reports

Formation of the Collateral Circulation Is Regulated by Vascular Endothelial Growth Factor-A and A Disintegrin and Metalloprotease Family Members 10 and 17

(2012) Jennifer L. Lucitti et al.   CIRCULATION RESEARCH

Treatment of Traumatic Brain Injury Using Zinc-Finger Protein Gene Therapy Targeting VEGF-A

(2012) Ishita Siddiq et al.   JOURNAL OF NEUROTRAUMA

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Rafael Lozano et al.   LANCET

Olfactory dysfunction in Parkinson disease

(2012) Richard L. Doty   Nature Reviews Neurology

Amyotrophic lateral sclerosis

(2011) Matthew C Kiernan et al.   LANCET

Olfactory deficits and cardiac 123I-MIBG in Parkinson's disease related to the LRRK2 R1441G and G2019S mutations

(2011) Javier Ruiz-Martínez et al.   MOVEMENT DISORDERS

New animal models of Parkinson's disease

(2011) Benjamin Dehay et al.   MOVEMENT DISORDERS

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

(2011) Berislav V. Zlokovic   NATURE REVIEWS NEUROSCIENCE

VEGF polymorphisms and serum VEGF levels in Parkinson's disease

(2011) Ebru Mihci et al.   NEUROSCIENCE LETTERS

Differences in Abundances of Cell-Signalling Proteins in Blood Reveal Novel Biomarkers for Early Detection Of Clinical Alzheimer's Disease

(2011) Mateus Rocha de Paula et al.   PLoS One

The effect of encapsulated VEGF-secreting cells on brain amyloid load and behavioral impairment in a mouse model of Alzheimer’s disease

(2010) Carlos Spuch et al.   BIOMATERIALS

Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease

(2010) Sara Van de Veire et al.   CELL

VEGF-expressing human umbilical cord mesenchymal stem cells, an improved therapy strategy for Parkinson’s disease

(2010) N Xiong et al.   GENE THERAPY

VEGF/VEGFR-2 changes in frontal cortex, choroid plexus, and CSF after chronic obstructive hydrocephalus

(2010) Jun Yang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

A Phase I Study of Aromatic L-Amino Acid Decarboxylase Gene Therapy for Parkinson's Disease

(2010) Shin-ichi Muramatsu et al.   MOLECULAR THERAPY

Systematic review of levodopa dose equivalency reporting in Parkinson's disease

(2010) Claire L. Tomlinson et al.   MOVEMENT DISORDERS

VEGF kinase inhibitors: how do they cause hypertension?

(2009) Pankaj Bhargava   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

High Pulsatility Flow Induces Adhesion Molecule and Cytokine mRNA Expression in Distal Pulmonary Artery Endothelial Cells

(2009) Min Li et al.   ANNALS OF BIOMEDICAL ENGINEERING

Hepatic fibrosis

(2009) Jingjing Jiao et al.   CURRENT OPINION IN GASTROENTEROLOGY

Dissociation between Vascular Endothelial Growth Factor Receptor-2 and Blood Vessel Density in the Caudate Nucleus after Chronic Hydrocephalus

(2009) Abhishek Deshpande et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

VEGF genetic variability is associated with increased risk of developing Alzheimer's disease

(2009) Roberto Del Bo et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Vascular endothelial growth factor B (VEGF-B) is up-regulated and exogenous VEGF-B is neuroprotective in a culture model of Parkinson's disease

(2009) Torsten Falk et al.   Molecular Neurodegeneration

Transforming growth factor-alpha induces neurogenesis and behavioral improvement in a chronic stroke model

(2009) M. Guerra-Crespo et al.   NEUROSCIENCE

Role and Therapeutic Potential of VEGF in the Nervous System

(2009) Carmen Ruiz de Almodovar et al.   PHYSIOLOGICAL REVIEWS

Neural Stem Cells Confer Unique Pinwheel Architecture to the Ventricular Surface in Neurogenic Regions of the Adult Brain

(2008) Zaman Mirzadeh et al.   Cell Stem Cell

Expression of transgenes in midbrain dopamine neurons using the tyrosine hydroxylase promoter

(2008) M S Oh et al.   GENE THERAPY

Aging and Sedentarism Decrease Vascularization and VEGF Levels in the Rat Substantia Nigra. Implications for Parkinson's Disease

(2008) Begoña Villar-Cheda et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Pulse Pressure and Pulse Wave Velocity Are Related to Cognitive Decline in the Baltimore Longitudinal Study of Aging

(2007) Shari R. Waldstein et al.   HYPERTENSION

Aging does not alter the number or phenotype of putative stem/progenitor cells in the neurogenic region of the hippocampus

(2006) Bharathi Hattiangady et al.   NEUROBIOLOGY OF AGING