Melatonin as a Therapy for Traumatic Brain Injury: A Review of Published Evidence

Melatonin attenuates traumatic brain injury-induced inflammation: a possible role for mitophagy

(2016) Chao Lin et al.   JOURNAL OF PINEAL RESEARCH

Melatonin attenuates neuronal apoptosis through up-regulation of K+-Cl−cotransporter KCC2 expression following traumatic brain injury in rats

(2016) Haijian Wu et al.   JOURNAL OF PINEAL RESEARCH

Melatonin Attenuates Early Brain Injury via the Melatonin Receptor/Sirt1/NF-κB Signaling Pathway Following Subarachnoid Hemorrhage in Mice

(2016) Lei Zhao et al.   MOLECULAR NEUROBIOLOGY

Targeting different pathophysiological events after traumatic brain injury in mice: Role of melatonin and memantine

(2016) Taha Kelestemur et al.   NEUROSCIENCE LETTERS

Hospitalizations and Emergency Department Visits for TBI in Ontario

(2016) Angela Colantonio et al.   CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES

Melatonin Preserves Blood-Brain Barrier Integrity and Permeability via Matrix Metalloproteinase-9 Inhibition

(2016) Himakarnika Alluri et al.   PLoS One

Pre-Clinical Traumatic Brain Injury Common Data Elements: Toward a Common Language Across Laboratories

(2015) Douglas H. Smith et al.   JOURNAL OF NEUROTRAUMA

Melatonin protects the brain from apoptosis by enhancement of autophagy after traumatic brain injury in mice

(2015) Ke Ding et al.   NEUROCHEMISTRY INTERNATIONAL

Differential effects of early postinjury treatment with neuroprotective drugs in a mouse model using diffuse reflectance spectroscopy

(2015) Ariel Shochat et al.   Neurophotonics

Reduction in traumatic brain injury-induced oxidative stress, apoptosis, and calcium entry in rat hippocampus by melatonin: Possible involvement of TRPM2 channels

(2014) Vehbi Yürüker et al.   METABOLIC BRAIN DISEASE

Melatonin reduces traumatic brain injury-induced oxidative stress in the cerebral cortex and blood of rats

(2014) Mustafa Nazıroğlu et al.   Neural Regeneration Research

Role of Melatonin in Traumatic Brain Injury and Spinal Cord Injury

(2014) Mehar Naseem et al.   TheScientificWorldJOURNAL

A double-blind, placebo-controlled intervention trial of 3 and 10 mg sublingual melatonin for post-concussion syndrome in youths (PLAYGAME): study protocol for a randomized controlled trial

(2014) Karen M Barlow et al.   Trials

Effect of Melatonin on Intracranial Pressure and Brain Edema Following Traumatic Brain Injury: Role of Oxidative Stresses

(2013) Fatemeh Dehghan et al.   ARCHIVES OF MEDICAL RESEARCH

Combination therapy with melatonin and dexamethasone in a mouse model of traumatic brain injury

(2013) Michela Campolo et al.   JOURNAL OF ENDOCRINOLOGY

Changing patterns in the epidemiology of traumatic brain injury

(2013) Bob Roozenbeek et al.   Nature Reviews Neurology

Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis

(2013) Yi Zhang et al.   NEUROBIOLOGY OF DISEASE

Simultaneous modulation of COX-2, p300, Akt, and Apaf-1 signaling by melatonin to inhibit proliferation and induce apoptosis in breast cancer cells

(2012) Jingshu Wang et al.   JOURNAL OF PINEAL RESEARCH

Incidence of traumatic brain injury in New Zealand: a population-based study

(2012) Valery L Feigin et al.   LANCET NEUROLOGY

The Melatonin MT1 Receptor Axis Modulates Mutant Huntingtin-Mediated Toxicity

(2011) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Posttreatment with uridine and melatonin following traumatic brain injury reduces edema in various brain regions in rats

(2010) Shruti V. Kabadi et al.   Annals of the New York Academy of Sciences

Sleep disturbance and melatonin levels following traumatic brain injury

(2010) J. A. Shekleton et al.   NEUROLOGY

Melatonin and minocycline for combinatorial therapy to improve functional and histopathological deficits following traumatic brain injury

(2010) Matthew L. Kelso et al.   NEUROSCIENCE LETTERS

The Antiapoptotic Activity of Melatonin in Neurodegenerative Diseases

(2009) Xin Wang   CNS Neuroscience & Therapeutics

Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease

(2009) James M. Olcese et al.   JOURNAL OF PINEAL RESEARCH

Endogenous Melatonin Increases in Cerebrospinal Fluid of Patients after Severe Traumatic Brain Injury and Correlates with Oxidative Stress and Metabolic Disarray

(2008) Marc A Seifman et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Melatonin attenuates calpain upregulation, axonal damage and neuronal death in spinal cord injury in rats

(2008) Supriti Samantaray et al.   JOURNAL OF PINEAL RESEARCH

Dual effects of melatonin on oxidative stress after surgical brain injury in rats

(2008) Steve Lee et al.   JOURNAL OF PINEAL RESEARCH

Influence of dietary melatonin on photoreceptor survival in the rat retina: An ocular toxicity study

(2007) Allan F. Wiechmann et al.   EXPERIMENTAL EYE RESEARCH