Doxycycline Impairs Mitochondrial Function and Protects Human Glioma Cells from Hypoxia-Induced Cell Death: Implications of Using Tet-Inducible Systems

An all-in-one, Tet-On 3G inducible PiggyBac system for human pluripotent stem cells and derivatives

(2017) Lauren N. Randolph et al.   Scientific Reports

Structure and Function of the Mitochondrial Ribosome

(2016) Basil J. Greber et al.   Annual Review of Biochemistry

The process of mammalian mitochondrial protein synthesis

(2016) Nicole Mai et al.   CELL AND TISSUE RESEARCH

Doxycycline inhibits the cancer stem cell phenotype and epithelial-to-mesenchymal transition in breast cancer

(2016) Le Zhang et al.   CELL CYCLE

Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: Treating cancer like an infectious disease

(2015) Rebecca Lamb et al.   Oncotarget

Tetracyclines Disturb Mitochondrial Function across Eukaryotic Models: A Call for Caution in Biomedical Research

(2015) Norman Moullan et al.   Cell Reports

Mitonuclear protein imbalance as a conserved longevity mechanism

(2013) Riekelt H. Houtkooper et al.   NATURE

Doxycycline Alters Metabolism and Proliferation of Human Cell Lines

(2013) Ethan Ahler et al.   PLoS One

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Synthesis of cytochrome c oxidase 2: a p53-dependent metabolic regulator that promotes respiratory function and protects glioma and colon cancer cells from hypoxia-induced cell death

(2011) C Wanka et al.   ONCOGENE

Retroviral and Transposon-Based Tet-Regulated All-In-One Vectors with Reduced Background Expression and Improved Dynamic Range

(2010) Niels Heinz et al.   HUMAN GENE THERAPY

Interactions of doxycycline with chemotherapeutic agents in human breast adenocarcinoma MDA-MB-231 cells

(2009) Faryar Foroodi et al.   ANTI-CANCER DRUGS

Antagonism of the mammalian target of rapamycin selectively mediates metabolic effects of epidermal growth factor receptor inhibition and protects human malignant glioma cells from hypoxia-induced cell death

(2009) Michael W. Ronellenfitsch et al.   BRAIN

In Vitro- and In Vivo-Induced Transgene Expression in Human Embryonic Stem Cells and Derivatives

(2007) Xiaofeng Xia et al.   STEM CELLS