Family-based genome scan for age at onset of late-onset Alzheimer's disease in whole exome sequencing data

Association analysis using next-generation sequence data from publicly available control groups: the robust variance score statistic

(2014) Andriy Derkach et al.   BIOINFORMATICS

Accuracy of imputation to infer unobserved APOE epsilon alleles in genome-wide genotyping data

(2014) Farid Radmanesh et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The genetic contributions of SNCA and LRRK2 genes to Lewy Body pathology in Alzheimer's disease

(2014) C. Linnertz et al.   HUMAN MOLECULAR GENETICS

Effects of Multiple Genetic Loci on Age at Onset in Late-Onset Alzheimer Disease

(2014) Adam C. Naj et al.   JAMA Neurology

Identification of rare variants in Alzheimer’s disease

(2014) Jenny Lord et al.   Frontiers in Genetics

2013 Alzheimer's disease facts and figures

(2013)   Alzheimers & Dementia

Genome scan in familial late-onset Alzheimer's disease: A locus on chromosome 6 contributes to age-at-onset

(2013) Wei Zhao et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Initial Assessment of the Pathogenic Mechanisms of the Recently Identified Alzheimer Risk Loci

(2013) Patrick Holton et al.   ANNALS OF HUMAN GENETICS

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease

(2013) Carlos Cruchaga et al.   NATURE

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

TREM2 is associated with the risk of Alzheimer's disease in Spanish population

(2013) Bruno A. Benitez et al.   NEUROBIOLOGY OF AGING

The CAMKK2-AMPK Kinase Pathway Mediates the Synaptotoxic Effects of Aβ Oligomers through Tau Phosphorylation

(2013) Georges Mairet-Coello et al.   NEURON

WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013

(2013) Jing Wang et al.   NUCLEIC ACIDS RESEARCH

The Macroeconomics of Dementia—Will the World Economy Get Alzheimer's Disease?

(2012) Sube Banerjee   ARCHIVES OF MEDICAL RESEARCH

Epidemiology of Dementias and Alzheimer’s Disease

(2012) Ana Luisa Sosa-Ortiz et al.   ARCHIVES OF MEDICAL RESEARCH

The role of large pedigrees in an era of high-throughput sequencing

(2012) Ellen M. Wijsman   HUMAN GENETICS

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Families

(2012) Carlos Cruchaga et al.   PLoS One

Study of Dementia in Swedish Twins

(2012) Margaret Gatz et al.   Twin Research and Human Genetics

Rare-Variant Association Testing for Sequencing Data with the Sequence Kernel Association Test

(2011) Michael C. Wu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome scan of age-at-onset in the NIMH Alzheimer disease sample uncovers multiple loci, along with evidence of both genetic and sample heterogeneity

(2011) Yoonha Choi et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

The Structure of Genetic Linkage Data: From LIPED to 1M SNPs

(2011) Elizabeth Thompson   HUMAN HEREDITY

Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP

(2011) Patricia Gómez-Suaga et al.   HUMAN MOLECULAR GENETICS

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

(2011)   LANCET

Genome-wide association analysis of age-at-onset in Alzheimer's disease

(2011) M I Kamboh et al.   MOLECULAR PSYCHIATRY

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

Recessive LAMC3 mutations cause malformations of occipital cortical development

(2011) Tanyeri Barak et al.   NATURE GENETICS

A linear complexity phasing method for thousands of genomes

(2011) Olivier Delaneau et al.   NATURE METHODS

Genome-Wide Association of Familial Late-Onset Alzheimer's Disease Replicates BIN1 and CLU and Nominates CUGBP2 in Interaction with APOE

(2011) Ellen M. Wijsman et al.   PLoS Genetics

Replication of CLU, CR1, and PICALM Associations With Alzheimer Disease

(2010) Minerva M. Carrasquillo et al.   ARCHIVES OF NEUROLOGY

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

(2010) Sudha Seshadri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Parkinson's disease: from monogenic forms to genetic susceptibility factors

(2009) S. Lesage et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Genome-wide association study reveals genetic risk underlying Parkinson's disease

(2009) Javier Simón-Sánchez et al.   NATURE GENETICS

A Groupwise Association Test for Rare Mutations Using a Weighted Sum Statistic

(2009) Bo Eskerod Madsen et al.   PLoS Genetics

Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE

(2008) Lars Bertram et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A genomic scan for age at onset of alzheimer's disease in 437 families from the NIMH genetic initiative

(2008) M. Ryan Dickson et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Mutational Analysis in Early-Onset Familial Dementia in the Japanese Population

(2008) Takeshi Ikeuchi et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Evaluation of coverage variation of SNP chips for genome-wide association studies

(2008) Mingyao Li et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Proper analysis of secondary phenotype data in case-control association studies

(2008) D. Y. Lin et al.   GENETIC EPIDEMIOLOGY