Mechanisms of Diabetes-Induced Endothelial Cell Senescence: Role of Arginase 1

Stress, cell senescence and organismal ageing

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Activation of Nrf2-mediated anti-oxidant genes by antrodin C prevents hyperglycemia-induced senescence and apoptosis in human endothelial cells

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Arginase Inhibition Improves Microvascular Endothelial Function in Patients With Type 2 Diabetes Mellitus

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Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy

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Arginase 2 promotes neurovascular degeneration during ischemia/reperfusion injury

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Angiotensin II limits NO production by upregulating arginase through a p38 MAPK–ATF-2 pathway

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Increased Oxidative and Nitrative Stress Accelerates Aging of the Retinal Vasculature in the Diabetic Retina

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Arginase: an old enzyme with new tricks

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1-Deoxynojirimycin attenuates high glucose-accelerated senescence in human umbilical vein endothelial cells

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Arginase 2 Deficiency Prevents Oxidative Stress and Limits Hyperoxia-Induced Retinal Vascular Degeneration

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Arginase 2 deficiency reduces hyperoxia-mediated retinal neurodegeneration through the regulation of polyamine metabolism

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Insights into the arginine paradox: evidence against the importance of subcellular location of arginase and eNOS

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Activated Rho Kinase Mediates Diabetes‐Induced Elevation of Vascular Arginase Activation and Contributes to Impaired Corpora Cavernosa Relaxation: Possible Involvement of p38 MAPK Activation

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Arginase inhibition mediates renal tissue protection in diabetic nephropathy by a nitric oxide synthase 3-dependent mechanism

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Akita Spontaneously Type 1 Diabetic Mice Exhibit Elevated Vascular Arginase and Impaired Vascular Endothelial and Nitrergic Function

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Arginase in retinopathy

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Arginase‐II Induces Vascular Smooth Muscle Cell Senescence and Apoptosis Through p66Shc and p53 Independently of Its l ‐Arginine Ureahydrolase Activity: Implications for Atherosclerotic Plaque Vulnerability

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Arginase as a mediator of diabetic retinopathy

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Positive crosstalk between arginase-II and S6K1 in vascular endothelial inflammation and aging

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Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout

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The role of arginase I in diabetes-induced retinal vascular dysfunction in mouse and rat models of diabetes

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Arginase inhibition alleviates hypertension associated with diabetes: Effect on endothelial dependent relaxation and NO production

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Angiotensin II-induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen-activated protein kinase/arginase pathway

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Arginase inhibition restores in vivo coronary microvascular function in type 2 diabetic rats

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Arginase 1 contributes to diminished coronary arteriolar dilation in patients with diabetes

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Diabetes-induced vascular dysfunction involves arginase I

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IGFBP7 reduces breast tumor growth by induction of senescence and apoptosis pathways

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Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway

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Arginase 2 Deletion Reduces Neuro-Glial Injury and Improves Retinal Function in a Model of Retinopathy of Prematurity

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Vascular dysfunction in retinopathy—An emerging role for arginase

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Diabetes-induced Coronary Vascular Dysfunction Involves Increased Arginase Activity

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