Mitochondrial BK Channel Openers CGS7181 and CGS7184 Exhibit Cytotoxic Properties

What do we not know about mitochondrial potassium channels?

(2016) Michał Laskowski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

SERCA, complex I of the respiratory chain and ATP-synthase inhibition are involved in pleiotropic effects of NS1619 on endothelial cells

(2016) Agnieszka Łukasiak et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hemin inhibits the large conductance potassium channel in brain mitochondria: A putative novel mechanism of neurodegeneration

(2014) Bartłomiej Augustynek et al.   EXPERIMENTAL NEUROLOGY

Paxilline inhibits BK channels by an almost exclusively closed-channel block mechanism

(2014) Yu Zhou et al.   JOURNAL OF GENERAL PHYSIOLOGY

Putative Structural and Functional Coupling of the Mitochondrial BKCa Channel to the Respiratory Chain

(2013) Piotr Bednarczyk et al.   PLoS One

Calpains, mitochondria, and apoptosis

(2012) M. A. Smith et al.   CARDIOVASCULAR RESEARCH

The potassium channel opener CGS7184 activates Ca2+ release from the endoplasmic reticulum

(2012) Antoni Wrzosek et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Glutamate-induced cell death in HT22 mouse hippocampal cells is attenuated by paxilline, a BK channel inhibitor

(2012) Bogusz Kulawiak et al.   MITOCHONDRION

Pharmacology of mitochondrial potassium channels: dark side of the field

(2010) Adam Szewczyk et al.   FEBS LETTERS

Immediate neuronal preconditioning by NS1619

(2009) Tamás Gáspár et al.   BRAIN RESEARCH

Calcium Ions Regulate K+ Uptake into Brain Mitochondria: The Evidence for a Novel Potassium Channel

(2009) Jolanta Skalska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Determination of the rate of K+ movement through potassium channels in isolated rat heart and liver mitochondria

(2008) Piotr Bednarczyk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A novel potassium channel in skeletal muscle mitochondria

(2008) Jolanta Skalska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

BK Channel Modulators: A Comprehensive Overview

(2008) Antonio Nardi et al.   CURRENT MEDICINAL CHEMISTRY

Large-conductance K+ channel opener CGS7184 as a regulator of endothelial cell function

(2008) Antoni Wrzosek et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

BK channel openers inhibit ROS production of isolated rat brain mitochondria

(2008) Bogusz Kulawiak et al.   EXPERIMENTAL NEUROLOGY

Novel 1,4-Benzothiazine Derivatives as Large Conductance Ca2+-Activated Potassium Channel Openers

(2008) Vincenzo Calderone et al.   JOURNAL OF MEDICINAL CHEMISTRY

Delayed neuronal preconditioning by NS1619 is independent of calcium activated potassium channels

(2008) Tamás Gáspár et al.   JOURNAL OF NEUROCHEMISTRY

Differential distribution of Ca2+-activated potassium channel β4 subunit in rat brain: Immunolocalization in neuronal mitochondria

(2008) M. Piwonska et al.   NEUROSCIENCE