Lengths of coding and noncoding regions of a gene correlate with gene essentiality and rates of evolution

Three Independent Determinants of Protein Evolutionary Rate

(2013) Sun Shim Choi et al.   JOURNAL OF MOLECULAR EVOLUTION

The relationship between the hierarchical position of proteins in the human signal transduction network and their rate of evolution

(2012) David Alvarez-Ponce   BMC EVOLUTIONARY BIOLOGY

Molecular Evolution in Nonrecombining Regions of the Drosophila melanogaster Genome

(2012) José L. Campos et al.   Genome Biology and Evolution

Expression level, cellular compartment and metabolic network position all influence the average selective constraint on mammalian enzymes

(2011) Corey M Hudson et al.   BMC EVOLUTIONARY BIOLOGY

Molecular Evolution, Mutation Size and Gene Pleiotropy: A Geometric Reexamination

(2011) P. Razeto-Barry et al.   GENETICS

Contrasting patterns of evolution following whole genome versus tandem duplication events in Populus

(2011) E. Rodgers-Melnick et al.   GENOME RESEARCH

Genome factor and gene pleiotropy hypotheses in protein evolution

(2010) Yanwu Zeng et al.   Biology Direct

Human functional genetic studies are biased against the medically most relevant primate-specific genes

(2010) Lili Hao et al.   BMC EVOLUTIONARY BIOLOGY

Deciphering the splicing code

(2010) Yoseph Barash et al.   NATURE

Fine-scale recombination rate differences between sexes, populations and individuals

(2010) Augustine Kong et al.   NATURE

Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing

(2010) Akihiro Fujimoto et al.   NATURE GENETICS

Systemic factors dominate mammal protein evolution

(2010) A. E. Vinogradov   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Reduced Effectiveness of Selection Caused by a Lack of Recombination

(2009) Andrea J. Betancourt et al.   CURRENT BIOLOGY

Localized network centrality and essentiality in the yeast–protein interaction network

(2009) Keunwan Park et al.   PROTEOMICS

Why Is the Correlation between Gene Importance and Gene Evolutionary Rate So Weak?

(2009) Zhi Wang et al.   PLoS Genetics

Evolutionary rates and centrality in the yeast gene regulatory network

(2009) Richard Jovelin et al.   GENOME BIOLOGY

Modeling an Evolutionary Conserved Circadian Cis-Element

(2008) Eric R. Paquet et al.   PLoS Computational Biology

Why Do Hubs in the Yeast Protein Interaction Network Tend To Be Essential: Reexamining the Connection between the Network Topology and Essentiality

(2008) Elena Zotenko et al.   PLoS Computational Biology