Single-step cloning-screening method: a new tool for developing and studying high-titer viral vector producer cells

Cellular targets for improved manufacturing of virus-based biopharmaceuticals in animal cells

(2014) Ana F. Rodrigues et al.   TRENDS IN BIOTECHNOLOGY

HEK293-Based Production Platform for γ-Retroviral (Self-Inactivating) Vectors: Application for Safe and Efficient Transfer of COL7A1 cDNA

(2014) Katharina Hennig et al.   Human Gene Therapy Clinical Development

Metabolic pathways recruited in the production of a recombinant enveloped virus: Mining targets for process and cell engineering

(2013) A.F. Rodrigues et al.   METABOLIC ENGINEERING

RD2-MolPack-Chim3, a Packaging Cell Line for Stable Production of Lentiviral Vectors for Anti-HIV Gene Therapy

(2013) Anna Stornaiuolo et al.   Human Gene Therapy Methods

Rapid titration of retroviral vectors using a β-lactamase protein fragment complementation assay

(2012) W Ou et al.   GENE THERAPY

Gene therapy matures in the clinic

(2012) Leonard W Seymour et al.   NATURE BIOTECHNOLOGY

First gene therapy nears landmark European market authorization

(2012) Nuala Moran   NATURE BIOTECHNOLOGY

Adaptation of retrovirus producer cells to serum deprivation: Implications in lipid biosynthesis and vector production

(2011) A.F. Rodrigues et al.   BIOTECHNOLOGY AND BIOENGINEERING

Lentivirus Production Is Influenced by SV40 Large T-Antigen and Chromosomal Integration of the Vector in HEK293 Cells

(2011) Leonor Gama-Norton et al.   HUMAN GENE THERAPY

Gene therapy finds its niche

(2011) Cormac Sheridan   NATURE BIOTECHNOLOGY

Large-Scale Production Means for the Manufacturing of Lentiviral Vectors

(2010) M. Schweizer et al.   CURRENT GENE THERAPY

Production of Retroviral Vectors: Review

(2010) Ana S. Coroadinha et al.   CURRENT GENE THERAPY

Retroviral Vector Performance in Defined Chromosomal Loci of Modular Packaging Cell Lines

(2010) L. Gama-Norton et al.   HUMAN GENE THERAPY

Large-Scale Manufacture and Characterization of a Lentiviral Vector Produced for Clinical Ex Vivo Gene Therapy Application

(2010) Otto-Wilhelm Merten et al.   HUMAN GENE THERAPY

Integrated Strategy for the Production of Therapeutic Retroviral Vectors

(2010) Manuel Carrondo et al.   HUMAN GENE THERAPY

Retroviral vector production under serum deprivation: The role of lipids

(2009) A.F. Rodrigues et al.   BIOTECHNOLOGY AND BIOENGINEERING

A new PG13-based packaging cell line for stable production of clinical-grade self-inactivating γ-retroviral vectors using targeted integration

(2009) R Loew et al.   GENE THERAPY

Impact of Retroviral Vector Components Stoichiometry on Packaging Cell Lines: Effects on Productivity and Vector Quality

(2007) Manuel J.T. Carrondo et al.   HUMAN GENE THERAPY

Engineering of a Stable Retroviral Gene Delivery Vector by Directed Evolution

(2007) Halong N Vu et al.   MOLECULAR THERAPY